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Postoperative Craniopharyngioma in a 10-Year-Old Girl Presenting with Central Precocious Puberty, Central Diabetes Insipidus, and Growth Hormone Deficiency 一名 10 岁女孩的颅咽管瘤术后症状：中枢性性早熟、中枢性糖尿病和生长激素缺乏症
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-15 DOI: 10.37275/bsm.v8i3.936
Nyoman Ananda Putri Prashanti, Putu Wahyu Dyatmika Tanaya, I Wayan Bikin Suryawan
{"title":"Postoperative Craniopharyngioma in a 10-Year-Old Girl Presenting with Central Precocious Puberty, Central Diabetes Insipidus, and Growth Hormone Deficiency","authors":"Nyoman Ananda Putri Prashanti, Putu Wahyu Dyatmika Tanaya, I Wayan Bikin Suryawan","doi":"10.37275/bsm.v8i3.936","DOIUrl":"https://doi.org/10.37275/bsm.v8i3.936","url":null,"abstract":"Background: Hypopituitarism is the most common endocrinology complication of postoperative craniopharyngioma. However, we found a 10-year-old girl with a history of postoperative craniopharyngioma presenting with central precocious puberty (CPP), central diabetes insipidus (CDI), and growth hormone deficiency (GHD). \u0000Case presentation: A 5-year-old girl experienced breast growth followed by menstruation six months later. The patient's weight was 19 kg (weight-for-age: P25-P50), height was 109 cm (height-for-age: P10-P25), and good nutritional status (Waterlow 90%). The stage of pubertal development was M2P2. There was a history of craniopharyngioma, and it was resected at the age of 2 years. After surgery, the patient developed CDI and has received desmopressin. No new tumour growth was found from evaluation with periodic MRIs every three years. After CPP was established, with increased serum levels of LH, FSH, and estradiol, GnRH agonist therapy was given at 100 mcg/kg BW every month. During five years of follow-up, the patient experienced clinical and laboratory improvement. However, the growth is only 3-4 cm/year (<P3) with short stature (height-for-age: <P3) and overweight. Low levels of IGF1 and GH were found in the stimulation test results, so the diagnosis of GHD was confirmed. The patient will receive growth hormone therapy and is expected to reach her potential genetic height (148.5 - 165.5 cm). \u0000Conclusion: Even though the craniopharyngioma tumour has been resected and no recurrence has occurred, it is crucial to evaluate the hormones produced by the pituitary thoroughly.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"16 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strangulated Incisional Hernia Post Appendectomy: A Rare Case Report 阑尾切除术后绞窄性切口疝：罕见病例报告
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-15 DOI: 10.37275/bsm.v8i3.927
Dewi Rahayu, Hendwell, Hendsun, Frengky Bermana
{"title":"Strangulated Incisional Hernia Post Appendectomy: A Rare Case Report","authors":"Dewi Rahayu, Hendwell, Hendsun, Frengky Bermana","doi":"10.37275/bsm.v8i3.927","DOIUrl":"https://doi.org/10.37275/bsm.v8i3.927","url":null,"abstract":"Background: Incisional hernia is a condition in which internal organs, such as the intestines, protrude through a previous surgical incision or suture. This occurs due to the failure of the abdominal wall to close properly. The closure of the abdominal wall is influenced by patient-related factors and technical factors during surgery. Incisional hernia following appendectomy is a rare condition, with an incidence rate of less than 0.12%. With this case report, the author aims to contribute to the literature on strangulated incisional hernia post-appendectomy. \u0000Case presentation: A 42-year-old male presented to the emergency department with complaints of right lower abdominal pain for the past three days. The patient reported a lump that had been intermittently present for the past nine years but became persistent three days ago. The patient had a history of appendectomy nine years ago. Vital signs were relatively stable, and physical examination revealed a bluish mass measuring 10x8x4 cm in the abdomen. Radiological abdominal assessment revealed a high-level obstructive ileus. Subsequently, the patient underwent a laparotomy, and a right hemicolectomy was performed, removing a segment measuring 50 cm from the ileocecal junction to the ascending colon. \u0000Conclusion: Incisional hernia following appendectomy is a rare complication, but it can occur due to various risk factors, such as surgical site infection, improper choice of suture material, and inappropriate wound closure technique. The management of this condition can involve the use of tension-free synthetic mesh in either laparotomy or laparoscopy.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"24 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic Management in Bacterial Pneumonia: A Narrative Literature Review 细菌性肺炎的抗生素管理：叙述性文献综述
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-15 DOI: 10.37275/bsm.v8i3.934
Yusri Herdika, Rohani Lasmaria
{"title":"Antibiotic Management in Bacterial Pneumonia: A Narrative Literature Review","authors":"Yusri Herdika, Rohani Lasmaria","doi":"10.37275/bsm.v8i3.934","DOIUrl":"https://doi.org/10.37275/bsm.v8i3.934","url":null,"abstract":"Pneumonia is an acute inflammation of the lung parenchyma caused by various types of microorganisms, such as bacteria, viruses, fungi, and parasites. The use of antibiotics is often faced with many types and inappropriate doses, and using antibiotics for too long can increase the risk of bacteria multidrug resistance (MDR). Therefore, the choice and dosage of antibiotics must be appropriate to reduce the rate of bacterial resistance. The increasing incidence of bacterial resistance is an indicator of failure in treating pneumonia because, apart from clinical improvement, optimal eradication of bacteria should also be the goal in every antibiotic administration. The aim of this literature review is to explain the basis for administering and selecting empiric antibiotics for pneumonia infections as well as appropriate antibiotic management and adequate especially in bacterial pneumonia, to provide a better prognosis.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"19 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aspergillosis in Lung Cancer: A Narrative Literature Review 肺癌曲霉菌病：叙述性文献综述
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-15 DOI: 10.37275/bsm.v8i3.935
Pofi Risanti, Yarsy, Sri Melati Munir
{"title":"Aspergillosis in Lung Cancer: A Narrative Literature Review","authors":"Pofi Risanti, Yarsy, Sri Melati Munir","doi":"10.37275/bsm.v8i3.935","DOIUrl":"https://doi.org/10.37275/bsm.v8i3.935","url":null,"abstract":"Aspergillosis is one of the complications of lung cancer and lung cancer treatment. Diagnosis of Aspergillosis in lung cancer, in general, is still a challenge because clinical symptoms and examination results are not typical, and risk factors often go unnoticed. To simplify the diagnosis of Aspergillosis, several criteria have been created based on the patient's condition, clinical and radiological features, and mycological laboratory examination. Doctors' vigilance still needs to be increased, examination facilities are still limited in certain cities, and diagnostic services have not been integrated, so management is not optimal. This literature review aims to increase doctors' knowledge and awareness regarding aspergillosis in lung cancer, which is an important step to improve the appropriate management of this disease.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"14 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracic Ultrasound: A Narrative Literature Review 胸部超声：叙述性文献综述
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-14 DOI: 10.37275/bsm.v8i3.933
Atikanur, Indi Esha
{"title":"Thoracic Ultrasound: A Narrative Literature Review","authors":"Atikanur, Indi Esha","doi":"10.37275/bsm.v8i3.933","DOIUrl":"https://doi.org/10.37275/bsm.v8i3.933","url":null,"abstract":"Ultrasonography (USG) is useful in diagnosing abnormalities in the thoracic area, such as pleural effusion, pneumothorax, consolidation, atelectasis, pulmonary edema, etc. The advantages of thoracic ultrasound are low cost, non-radiation, non-invasive, easy to carry, short examination time, and a dynamic aspect that can be seen during the examination. Thoracic ultrasound can be used to guide thoracentesis procedures, chest tube placement, and aspiration of lung abscesses. Ultrasound can be substituted as a computed tomography scan (CT-Scan) as a guide for aspiration and biopsy of the lung parenchyma, pleura, and chest wall. Portable and compact ultrasonography provides the opportunity for ultrasound examinations to become a routine part of an examination, like a stethoscope. Ultrasonography also has limitations in patients with subcutaneous emphysema, peripheral edema, and obesity. Ultrasound examination is very dependent on the experience and abilities of the operator.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"23 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138971933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidural Anesthesia in Management of Pregnant Eissenmenger’s Syndrome Patient Undergoing Caesarean Section 硬膜外麻醉在管理接受剖腹产手术的艾森曼格综合征孕妇中的应用
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-14 DOI: 10.37275/bsm.v8i2.932
I. G. N. B. Jayantha Ananda, Tjahya Aryasa, Tjokorda Gde Agung Senapathi
{"title":"Epidural Anesthesia in Management of Pregnant Eissenmenger’s Syndrome Patient Undergoing Caesarean Section","authors":"I. G. N. B. Jayantha Ananda, Tjahya Aryasa, Tjokorda Gde Agung Senapathi","doi":"10.37275/bsm.v8i2.932","DOIUrl":"https://doi.org/10.37275/bsm.v8i2.932","url":null,"abstract":"Background: Eisenmenger syndrome is very rare in pregnant women. Debates remain concerning the management of Eisenmenger syndrome in this patient population, and the prognosis is unclear in terms of maternal and fetoneonatal outcomes. Managing anesthesia in maternal patients with a cardiac abnormality might be particularly difficult because these individuals have inadequate circulatory reserves and altered maternal cardiovascular physiology. \u0000Case presentation: We present a 26-year-old 34 weeks pregnant woman with Eisenmenger’s syndrome (ES) scheduled for an elective caesarean section. The clinical findings reveal slight tachypnea with peripheral oxygen saturation of 82% with oxygen supplementation using a cannula at 3 lpm. The patient's baseline hemodynamics are stable, but a third-degree murmur is heard in the 3rd and 4th left intercostal space. The patient was managed with epidural anesthesia using bupivacaine 0.5% 20 ml without adjuvant. The epidural catheter was inserted in an interspinous process between L3-L4. The surgery was done in 90 minutes with stable hemodynamics, and postoperatively, the patient was monitored in the intensive cardiac care unit (ICCU). \u0000Conclusion: Epidural anesthesia has been shown to provide favorable outcomes due to its slow onset and reducing the likelihood of abrupt hemodynamic changes.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138971948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mixed Type Basal Cell Carcinoma Treated with Excision and Defect Closure Using Advancement Flap: A Case Report 混合型基底细胞癌采用切除术和推进皮瓣缝合术治疗：病例报告
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-14 DOI: 10.37275/bsm.v8i2.931
I. Gusti, Nyoman Darmaputra, Ketut Kwartantaya Winaya, Adelia Suryani, Herman Saputra, Putu Setiani
{"title":"Mixed Type Basal Cell Carcinoma Treated with Excision and Defect Closure Using Advancement Flap: A Case Report","authors":"I. Gusti, Nyoman Darmaputra, Ketut Kwartantaya Winaya, Adelia Suryani, Herman Saputra, Putu Setiani","doi":"10.37275/bsm.v8i2.931","DOIUrl":"https://doi.org/10.37275/bsm.v8i2.931","url":null,"abstract":"Background: Basal cell carcinoma (BCC) is a localized malignant tumor in the basal layer of the epidermis thought to be the result of prolonged sun exposure and associated with gene mutations in most cases. Although rarely metastazises, BCC can cause high levels of morbidity due to its locally destructive nature. There are several modalities for managing BCC, and the defect caused by the lesion can reconstructed by local flap. \u0000Case presentation: We present a 55-year-old woman with a chief complaint of a blackish lump on the left maxillary region, growing bigger, and frequent episodes of bleeding. The lesion was excised and followed by histopathological examination, which revealed mixed subtype BCC. Closure of the defect with an advancement flap was performed with favorable results. \u0000Conclusion: Surgical excision is the best option for managing BCC, while a skin flap is preferred to close defects for lesions on the cheek. \u0000 ","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"755 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138974012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuberculosis with Drug-Induced Hepatitis: A Narrative Literature Review 结核病合并药物性肝炎：文献综述
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-13 DOI: 10.37275/bsm.v8i2.929
Riska Yuliana, Zarfiardy Aksa, Fauzi, Article Info
{"title":"Tuberculosis with Drug-Induced Hepatitis: A Narrative Literature Review","authors":"Riska Yuliana, Zarfiardy Aksa, Fauzi, Article Info","doi":"10.37275/bsm.v8i2.929","DOIUrl":"https://doi.org/10.37275/bsm.v8i2.929","url":null,"abstract":"Tuberculosis (TB) is an infectious disease that is a global health problem. The problem is that 5-28% of patients receiving tuberculosis treatment suffer from drug-induced hepatitis on antituberculosis drugs (OAT). The clinical picture should be differentiated from other liver diseases. The level of symptoms varies from asymptomatic to symptomatic, such as nausea, vomiting, abdominal pain, jaundice, hepatomegaly, and increased liver function. OAT use is stopped if clinical symptoms are found and ALT/AST increases ≥3 times, or if there are no symptoms but there is an increase in bilirubin ≥2 mg/dl or ALT/AST values ≥5 times without clinical symptoms. The use of OAT can be continued, but with supervision, if there are no clinical symptoms and the increase in ALT/AST is <2 times and the bilirubin value is <2 mg/dl. Treatment can be carried out again by reintroducing OATs one by one according to ATS recommendations.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"8 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139005534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flexi-rigid Pleuroscopy in Diagnostics of Malignancy: A Narrative Literature Review 诊断恶性肿瘤的柔性硬膜外腔检查：文献综述
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-12 DOI: 10.37275/bsm.v8i2.925
Salmiyah, Indra Yovi, Article Info
{"title":"Flexi-rigid Pleuroscopy in Diagnostics of Malignancy: A Narrative Literature Review","authors":"Salmiyah, Indra Yovi, Article Info","doi":"10.37275/bsm.v8i2.925","DOIUrl":"https://doi.org/10.37275/bsm.v8i2.925","url":null,"abstract":"Pleuroscopy is a less invasive treatment that allows access to the pleural cavity with the use of both visual and surgical equipment. This technique can be conducted with local anesthesia and mild sedation. Pleuroscopy is a medical procedure used for both diagnosis and treatment in the pleural cavity. Pleuroscopy enables direct observation of the pleural surface, enhancing the safety of procedures such as pleural biopsy, pleural fluid drainage, and pleurodesis. One purpose is to assist in verifying the diagnosis of cancer. This review was aimed to describe the use of flexi-rigid pleuroscopy in malignancy.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"30 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139007344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathogenesis and Minimally Invasive Management of Subcutaneous Emphysema: A Narrative Literature Review 皮下气肿的发病机制和微创治疗：文献综述
Bioscientia Medicina : Journal of Biomedicine and Translational Research Pub Date : 2023-12-12 DOI: 10.37275/bsm.v8i2.928
Said Tryanda, Syafitra, Sri Indah Indriani, Article Info
{"title":"Pathogenesis and Minimally Invasive Management of Subcutaneous Emphysema: A Narrative Literature Review","authors":"Said Tryanda, Syafitra, Sri Indah Indriani, Article Info","doi":"10.37275/bsm.v8i2.928","DOIUrl":"https://doi.org/10.37275/bsm.v8i2.928","url":null,"abstract":"Subcutaneous emphysema is the result of air infiltrating the subcutaneous and soft tissues. The prevalence of subcutaneous emphysema varies between 0.43% and 2.34%. Subcutaneous emphysema typically results in mild symptoms, poses no significant risk, and does not necessitate specific medical intervention. Pathologies affecting underlying tissues can exhibit greater severity and pose a risk to life. Subcutaneous emphysema is a challenge in terms of how to handle it. The treatment should initiate a focused endeavor to determine the underlying etiology of subcutaneous air dissection. This literature review focuses on subcutaneous emphysema, specifically exploring its pathogenesis and therapy strategies for people with this condition.","PeriodicalId":102064,"journal":{"name":"Bioscientia Medicina : Journal of Biomedicine and Translational Research","volume":"24 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139009277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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