Chirurgie; memoires de l'Academie de chirurgie最新文献

{"title":"[Klatskin tumor. A study of 15 resected cases].","authors":"E Santoro, M Sacchi, F Carboni, R Santoro","doi":"10.1016/s0001-4001(99)80055-5","DOIUrl":"https://doi.org/10.1016/s0001-4001(99)80055-5","url":null,"abstract":"Study aim: Klatskin tumors are rare. Prognosis is still poor, and long term survival can be expected only after surgery, which is the treatment of choice. The aim of this study is to report the results of 15 resected cases and, by analysis of the literature, to emphasize the progress of the surgical treatment in hilar cholangiocarcinoma.Patients and methods: Between 1990 and 1998, 27 patients affected by Klatskin tumor were observed. Eight women and seven men underwent surgical resection. The mean age was 59 years. Thirteen patients (48%) had curative resection (7 hilar resection (HR), 5 HR combined with partial hepatectomy (PH) and 1 HR + PH with portal vein resection). Two patients had palliative resection and surgical drainage.Results: One in-hospital death occurred right after hepatectomy with portal vein resection (6.6%). Postoperative morbidity was 40%. Patients were regularly followed. Ten patients died and 5 were alive at the time of this study. The 1, 2 and 3-year survival after a curative resection was 84%, 54% and 34%. The median survival was 28.5 months. Lymph node involvement did not show a statistically significant difference on median survival between the positive group and the negative group (26.2 vs 29.8 months) because of the small number of patients. Survival after hilar resection at 1, 2, 3, and 5 years was 100%, 57.1%, 28.6% and 0%. Four out of the 6 patients who underwent hilar resection combined with partial hepatectomy were still alive 1, 23, 29, 38 months after resection. Hepatectomy increased mortality (16% vs 0%). Palliative biliary resection and surgical drainage were successfully performed in 2 patients.Conclusion: Aggressive surgical treatment of Klatskin tumor can improve the survival of patients. Careful pre-operative management has to be carried out by a multidisciplinary approach including surgeons, hepatologists, radiologists and pathologists. Hepatic resection including the caudate lobe is often performed in order to obtain microscopic tumor-free margins and curative resection (R0). Biliary drainage and treatment of cholangitis is mandatory before surgery in order to improve the surgical outcome. Surgical treatment is characterized by high technical difficulties, and better results can be achieved by hepatobiliary surgical teams.","PeriodicalId":10182,"journal":{"name":"Chirurgie; memoires de l'Academie de chirurgie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21218098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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[Consensus conference. Prevention, detection and management of colon cancer. Brief report]. [共识会议。结肠癌的预防、检测和治疗。简短的报告)。

Chirurgie; memoires de l'Academie de chirurgie Pub Date : 1998-04-01

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[Orbital metastasis of prostatic cancer. Clinical and therapeutic aspects. Apropos of a case (clinical case)]. 前列腺癌的眼眶转移。临床和治疗方面。关于一个病例(临床病例)]。

Chirurgie; memoires de l'Academie de chirurgie Pub Date : 1997-01-01

J Aubert, J Irani, P Saint-Blancat

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