Chinese Journal of Optometry & Ophthalmology最新文献

{"title":"The Practice and Effectiveness of COVID-19 RNA Detection in the Prevention and Control of Ophthalmic Hospital","authors":"Meiqin Zheng, Youpei Wang, Yunfeng Gu, Liping Mao, Wencan Wu, Wei Chen, Xinping Yu, Dingxing Ye, Y. Liang, J. Qu","doi":"10.3760/CMA.J.CN115909-20200303-00063","DOIUrl":"https://doi.org/10.3760/CMA.J.CN115909-20200303-00063","url":null,"abstract":"Objective: \u0000To explore a practical system of precision prevention and control against Corona Virus Disease 19 (COVID-19) for eye hospitals by emphasizing on systematic and standardized virus RNA detection procedures. \u0000 \u0000 \u0000Methods: \u0000To include standardized virus RNA detection along with blood routine test (BRT), C-reactive protein (CRP) and serum amyloid A (SAA) into preoperative screening test items for ocular surgical patients and to provide virus RNA detection for returned employees between 24 February 2020 and 2 March 2020. In addition, a questionnaire is designed to investigate the acceptability of nasopharyngeal swab sampling and the influence of virus RNA detection results on mental status of the examinee. \u0000 \u0000 \u0000Result: \u000099 examination results showed a certain percentage of abnormal, among which 13 cases showing increase in SAA, 12 cases showing decrease and 5 cases showing increase in lymphocyte count (LYM), 1 case showing decrease and 11 cases showing increase in white blood count (WBC), 2 cases showing increase in CRP. All cases showing negative in COVID-19 RNA detection, including examined patients and 33 employees of the Eye Hospital.11.7% of respondents reported a low acceptance score for nasopharyngeal swab sampling. The proportion of the examinees with higher mental stress scores before and after the virus RNA detection was 46.7% and 6.7% respectively. \u0000 \u0000 \u0000Conclusion: \u0000The detection procedures can offer objective basis for preoperative screening and differential diagnosis, whilst largely eliminating the possibility of transmission via asymptomatic infected individuals. On the other hand, the negative result of virus RNA detection is beneficial in adjusting patient’s preoperative psychological state and relieving the mental stress of medical staff during the epidemic. \u0000 \u0000 \u0000Key words: \u0000COVID-19; Infection; epidemic prevention and control; RNA detection; ophthalmology; effectiveness","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91437384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correct Choice of Goggles and Anti-fog Guidance Duringthe Epidemic Period of COVID-19","authors":"Hu Xiaoqiong, J. Qu, Chen’ Yanyan, Zhang Peihua, Zhang Chunmei, Zheng Xiuyun","doi":"10.3760/CMA.J.CN115909-20200301-00054","DOIUrl":"https://doi.org/10.3760/CMA.J.CN115909-20200301-00054","url":null,"abstract":"During the epidemic period of COVID-19, medical staff do all kinds of effective protection in order to avoid virus infection. Masks, protective clothing and goggles are essential for preventing viral infections. It was found that most goggles worn by medical staff could fog up quickly. This situation will block vision, increase risks and interfere with clinical works, nurses can’t operate effectively, doctors can’t diagnose and treat accurately. Patients are delayed in emergency rescue, and improper protection even leads to cross infection in hospital. After literature review and clinical practice, combined with professional knowledge, we proposed how to choose protective goggles correctly, and seven methods of anti-fog. This study was expected to be helpful to the medical workers in the prevention and control of COVID-19 \u0000 \u0000Key words: \u0000COVID-19; goggle; correct choice; anti-fog guidance","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81778329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2019-nCoV and Eye, What We Know and What We Should Do","authors":"Zhou Xiangtian, J. Qu","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.0001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.0001","url":null,"abstract":"A high contagious virus - Novel Coronavirus (2019-nCoV) is proved to be the pathogen causing a global outbreak of Novel coronavirus pneumonia (NCP), which is threatening the global public health. This article preliminarily reviews several different aspects, including the characteristics of 2019-nCoV, the anatomical connection between ocular surface and respiratory tract, previous work on the link between respiratory virus and ocular complication,and the data of Angiotension-converting enzyme 2 (ACE2) receptor expression and molecular detection of SARS virus in tear.Based on these reviews, intervention measures are advised for ophthalmic practitioner, whilst suggestions areindicated forfurther clinical and basic investigations in the future. \u0000 \u0000Key words: \u0000novel coronavirus (2019-nCoV); novel coronavirus pneumonia(NCP); eye; interventions","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88095204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of Macular Microvascular Changes in Patients with Systemic Lupus Erythematosus","authors":"Lulu Bao, Hong Wang, Yufei Wu, Rong Zhou, M. Shen, Qi Chen","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.008","url":null,"abstract":"Objective: \u0000To observe the characteristics of early macular microvascular changes in patients with systemic lupus erythematosus using optical coherence tomography angiography (OCTA). \u0000 \u0000 \u0000Methods: \u0000This was a retrospective series of case study. Thirty-one patients (62 eyes) who were diagnosed with SLE by the Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University from May to November 2018, were divided into a lupus retinopathy (LR) group of 10 patients (17 eyes) and a non-lupus retinopathy group of 24 patients (45 eyes). At the same time, 35 healthy subjects (35 eyes) who were matched by age and sex with the disease groups were recruited as a control group. All subjects had a 3 mm×3 mm area of the macula scanned by OCTA to obtain superficial and deep retinal microvascular images of the macular area, and retinal blood flow density maps were skeletonized and analyzed by a custom automated algorithm. The total annular zone (TAZ), with a diameter of 2.5 mm, was obtained after excluding the foveal avascular zone (FAZ, 0.6 mm), and the superficial and deep retinal skeletonized capillary densities (RCD) of the TAZ were further divided into 4 regions (S, T, I, N). In addition, disease activity of the patients was assessed using the SLE disease activity index (SLEDAI). Data analysis was performed using a t test and analysis of variance. \u0000 \u0000 \u0000Results: \u0000The RCD of the superficial retinal capillary plexus (SRCP) were found to be significantly lower in the NLR and LR groups than in the control group, and the LR group was even lower than the NLR group and the difference was significant (P<0.05). In the deep retinal capillary plexus (DRCP), the difference between the three groups was not as obvious as that in the superficial layer. Only the RCD of the LR group in the N region was significantly lower than that in the NLR group (P=0.022), which were also lower than those in the control group (P<0.05) except for the T region. In addition, the score of SLEDAI in the LR group was significantly higher than in the NLR group (P=0.006), and the incidence of SLE complications such as lupus nephritis and neuropsychiatric SLE were higher in the LR group (50% vs. 25%, 10% vs. 4% respectively). \u0000 \u0000 \u0000Conclusions: \u0000OCTA can effectively detect early changes in macular microvascular morphology in the patients with SLE. In patients with SLE without significant fundus and visual impairment, the RCD of SRCP is significantly altered, suggesting that it may be used as an early biomarker for monitoring SLE retinal damage. \u0000 \u0000 \u0000Key words: \u0000systemic lupus erythematosus; retinal capillary density; lupus retinopathy; score of systemic lupus erythematosus disease activity index","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"155 1","pages":"44-50"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75681765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Application Value of a Preset Marking Line in Lacrimal Endoscopic Surgery","authors":"Pan Xiao, D. Yang, Zhengru Huang, Qian Xing, Jian-Jun Tao, Yifang Meng, Jian Li, Jiong Lu","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.011","url":null,"abstract":"Objective: \u0000To explore the clinical application value of a preset marking line in lacrimal endoscopic surgery and evaluate its effect on surgical complications. \u0000 \u0000 \u0000Methods: \u0000This was a prospective analysis of clinical data from 60 patients (60 eyes) with lacrimal duct obstruction who had lacrimal endoscopic surgery in Changshu No.2 People's Hospital from June 2015 to December 2018. All patients were divided into two groups, a control group or observation group according to the even or odd numbers assigned to hospital patients. The control group (odd numbers) had no intra-surgery preset marking line. The observation group (even numbers) had an intra-surgery preset marking line. The complications of lacrimal duct mucosa injury, hemorrhage, perforation (false passage), eyelid edema and postoperative hemorrhage were observed and recorded. The data were analyzed by a Chi-square test. \u0000 \u0000 \u0000Results: \u0000In the observation group, the number of preset marking lines could be clearly observed during surgery, and combined with the position of the lacrimal endoscope, could be determined by the anatomical characteristics of the lacrimal passage. One marker line could be observed in the lacrimal canaliculi. The convergence of two marker lines could be observed in the common canaliculus. Two marker lines with an enlarged space could be observed in the lacrimal sac. Two marker lines with mucosal folds could be observed in the nasolacrimal duct. The incidence of lacrimal mucosal injury was 16% (χ2=8.543, P=0.003), hemorrhage incidence was 13% (χ2=8.718, P=0.003) and eyelid edema incidence was 10% (χ2=4.069, P=0.044) in the observation group, which were significantly lower than the incidences in the control group (52%, 52% and 35%, respectively). One case of perforation (false passage) occurred in the control group, which was not statistically significant compared with the observation group (χ2=0.001, P=0.973). There was no statistically significant difference in the incidence of postoperative hemorrhage between the groups (χ2=1.898, P=0.168). Moreover, all patients in the two groups had a small amount of hemorrhage, which did not affect the operation after intraoperative water injection. Patients with a small amount of postoperative hemorrhage stopped bleeding within 2 days. \u0000 \u0000 \u0000Conclusions: \u0000The application of preset marking lines for lacrimal endoscopic surgery can better control the endoscopic examination and surgery, and can accurately identify the location site of the surgery, which can reduce the incidence of surgical complications. \u0000 \u0000 \u0000Key words: \u0000lacrimal endoscope; lacrimal duct stents; preset marker line; lacrimal duct obstruction","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"39 1","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74843515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress on Ophthalmic Changes in Astronauts Induced by a Microgravity Environment and the Related Mechanism","authors":"Chenchen Zhang, Jia Li, Lingzhi Niu, Yuanping Wang","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.013","url":null,"abstract":"A series of ophthalmic changes can occur after astronauts enter the microgravity environment. If these changes are not intervened or treated in a timely manner, it will cause long-term or permanent visual impairment to astronauts, which will not only affect the execution of flight missions, but also threaten the personal safety of astronauts. Although the precise mechanism of these ophthalmic changes in astronauts is still unclear, related studies have found that when astronauts enter the microgravity environment, there is intracranial pressure elevation, nervous system changes, biochemical changes, and lymphoid and venous circulation disorders, which may be involved in the occurrence and development of the disease. This paper summarizes these ophthalmic changes over a period of the last 50 years at home and abroad and their possible mechanisms after astronauts enter the microgravity environment. We want to identify the preventive and treatment measures for these ophthalmic changes, and provide relevant theoretical support for the screening and training of astronauts. \u0000 \u0000 \u0000Key words: \u0000microgravity; simulated microgravity; astronaut; visual impairment; space flight-associated neuro-ocular syndrome","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"5 1","pages":"72-77"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85287414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Inter-Arm Systolic Blood Pressure Differences on Visual Field Progression in Primary Glaucoma","authors":"Qiong Liu, Minna Rong, Wenhui Deng, Qin Wang, Xing Cao, Dan Zhou, Changhua Ye","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.006","url":null,"abstract":"Objective: \u0000To investigate the effects of inter-arm systolic blood pressure differences (IASBPD) on visual field progression in primary glaucoma patients with controlled intraocular pressure. \u0000 \u0000 \u0000Methods: \u0000In this prospective clinical study, 69 primary glaucoma patients (69 eyes) who had visited Changsha Aier Eye Hospital from August 2013 to November 2018 and who had at least 5 reliable visual reportson file were selected. According to the guided progression analysis (GPA) of the Humphrey Field Analyzer, subjects were divided into two groups, the visual field progression group and the non-progression group. All of the patients underwent multiple sets of sequential blood pressure measurements on both arms. A student t test, Fisher's exact test and logistic regression analysis were used for data analysis. \u0000 \u0000 \u0000Results: \u0000Thirty-four patients (34 eyes) were included in the analysis, among which 15 patients (15 eyes) were in the progression group and the other 19 patients (19 eyes) were in non-progression group. The IASBPD of the two groups was 10.6±9.0 mmHg (1 mmHg=0.133 kPa) and 5.3±2.8 mmHg, respectively, and IASBPD in the progression group was 5.26 mmHg (95% credibility interval: 0.14-10.37 mmHg) higher than that in the non-progression group (t=-2.177, P=0.045). There were no significant differences in pulse pressure, mean arterial pressure, or diastolic ocular perfusion pressure between the two groups (t=0.946, -1.118, -1.967, all P>0.05). Logistic regression analysis showed that an IASBPD of ≥10 mmHg was a risk factor for visual field progression (OR=20.310, P=0.022). Participants were also stratified into two groups with an IASBPD of <10 mmHg (n=26) and ≥10 mmHg (n=8). The rates of visual field progression for the two groups were 30.8% and 87.5%, and rates of retinal nerve fiber layer thickness progression were 42.3% and 87.5%, respectively (P=0.011, 0.030). \u0000 \u0000 \u0000Conclusions: \u0000Increased IASBPD may be one of the risk factors for visual field progression in primary glaucoma patients with controlled intraocular pressure. \u0000 \u0000 \u0000Key words: \u0000primary glaucoma; intraocular pressure; visual field; inter-arm systolic blood pressure differences","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"53 1 1","pages":"32-38"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77469577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Overnight Orthokeratology on the Ocular Surface and Meibomian Glands in Children and Adolescents","authors":"Li Yang","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.009","url":null,"abstract":"Objective: \u0000To investigate the effect of overnight orthokeratology (OOK) on the ocular surface and changes in meibomian gland morphology in children and adolescents with myopia. \u0000 \u0000 \u0000Methods: \u0000In this prospective cohort study, choosing myopia children from the Second Affiliated Hospital of Zhejiang Chinese Medical University, sixty myopic patients (60 eyes) with OOK were selected as the OOK group, and 60 patients (60 eyes) with eye glasses were selected as the glasses group. The following tests were performed before OOK and eyeglass wear and after 1, 3, 6 and 12 months of wear. Tests included ocular surface disease index (OSDI) questionnaire, noninvasive tear break-up time (NIBUT), tear meniscus height (TMH), corneal epithelial staining (CSF), and meiboscore using noncontact meibography. The effect of OOK wear on the ocular surface and changes that occurred were evaluated and summarized by comparing the differences between these two groups. \u0000 \u0000 \u0000Results: \u0000There were no significant differences in the OSDI score or tear meniscus height between these two groups. The NIBUT of the OOK group showed a significant decrease after 6 and 12 months of lens wear (both P<0.05). There were no statistically significant differences at other time points. Corneal fluorescence staining in the OOK group increased after wearing the lenses (χ2=19.511, P=0.013), but there were no statistically significant differences at the other time points. The score of the meibomian gland orifice in the OOK group was slightly increased before wearing the lenses and after 1, 3 and 6 months, but the differences were not statistically significant. The final 12 months were significantly higher than before wearing eye glasses and 1 month after wearing eye glasses, and the difference was statistically significant (P<0.05). \u0000 \u0000 \u0000Conclusions: \u0000It is relatively safe to wear OOK lenses overnight. Short-term wear of OOK will not cause discomfort and it will not reduce tear meniscus height or the amount of tear secretion in the short term, however, it reduces the stability of the tear film and increases the corneal fluorescence staining score. OOK lens wear affected meibomian gland function. In particular, the upper meibomian gland changed first. \u0000 \u0000 \u0000Key words: \u0000orthokeratology; ocular surface; meibomian glands; children and adolescents","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"16 1","pages":"51-57"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81694169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observation on the Functioning of the Anterior Chamber Angle after Combined Glaucoma and Cataract Surgery in the Chronic Phase of Acute Angle-Closure Glaucoma with Cataract","authors":"Y. Chu, Xiao-yuan Yang, Haiyan Zhu, Hai-Jia Li, Yangzeng Dong","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.002","url":null,"abstract":"Objective: \u0000To investigate the functioning of the anterior chamber angle after combined surgery in the treatment of the chronic phase of acute angle-closure glaucoma with cataract. \u0000 \u0000 \u0000Methods: \u0000A retrospective analysis was performed on 37 patients (37 eyes) in the chronic phase of acute angle-closure glaucoma with cataract who were treated in the glaucoma center of Henan Provincial People's Hospital from November 2017 to March 2018: All patients were treated with drugs after an acute attack for 3-14 days; preoperative intraocular pressure (IOP) was higher than 21 mmHg; gonioscopic examination: angle closure >2 quadrant; ultrasound biomicroscopy (UBM): Anterior chamber shallow, peripheral iris root and trabecular meshwork attachment range >2 quadrant; lens nuclear turbidity ≥Ⅲ. All patients underwent conventional double-incision surgery combined with trabeculectomy, phacoemulsification cataract extraction, intraocular lens implantation, and angle separation. No anti-metabolite drugs were used during the surgery. The scleral flap was tightly closed with an adjustable suture. The best corrected visual acuity (BCVA), IOP, central anterior chamber depth, angle opening range and filtration bleb formation were observed before and after surgery. The Wilcoxon test, analysis of variance, paired t test and Pearson correlation were used to analyze the observation index. \u0000 \u0000 \u0000Results: \u0000At 7 days after surgery: The mean IOP was 18.8±1.7 mmHg, which was significantly lower than IOP before surgery (t=16.562, P 2 quadrants after surgery, and there was no correlation between postoperative IOP and preoperative anterior angle (r=0.016, P=0.926); the depth of the central anterior chamber was deeper than before surgery (t=-25.195, P<0.001); the postoperative BCVA of 33 patients was improved compared with BCVA before surgery, the BCVA of 4 patients did not improve, the difference in BCVA before and after surgery was statistically significant (Z=-5.017, P<0.001); 5 patients had functional filtering blebs formation in the upper conjunctiva, 32 patients had no obvious filtering blebs after surgery, ultrasound biomicroscopy also confirmed that no effective filtering blebs formed under the conjunctiva. \u0000 \u0000 \u0000Conclusions: \u0000For patients in the chronic phase of acute angle-closure glaucoma with cataract, combined trabeculectomy plus cataract surgery plus angle separation can effectively reduce intraocular pressure. The decrease in intraocular pressure is likely to depend on the recovery of the function of the trabecular meshwork, rather than to rely on the establishment of an external filtration channel. \u0000 \u0000 \u0000Key words: \u0000acute angle-closure glaucoma; chronic phase; glaucoma and cataract combined surgery; the function of anterior chamber angle","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"17 4 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82935987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Measurement of Iris Curvature and Its Application in Evaluating the Changes in Iris Curvature in Primary Angle Closure Suspect","authors":"Zhiwei Xu, Haijian Wu","doi":"10.3760/CMA.J.ISSN.1674-845X.2020.01.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2020.01.003","url":null,"abstract":"Objective: \u0000To evaluate the accuracy of the quantitative measurement of iris curvature by Rhinoceros and to assess the changes iniris curvature in primary angle closure suspect after laser periphery iridectomy (LPI). \u0000 \u0000 \u0000Methods: \u0000This was a prospective study. Sixteen patients (16 eyes) with primary angle closure suspect (PACS) who planned to undergo LPI treatment in Taizhou Municipal Hospital were selected. The anterior segment images of different axes were captured by Allegro Oculyzer. The curvature radius of the anterior iris surface was quantitatively measured by Rhinoceros 5.0. The repeatability of image capturing and image measurement was assessed. The iris curvature of the patients with PACS was compared before and after LPI. Sixteen normal persons (16 eyes) matched for age, sex, and pupil size were selected as the control group. The iris curvature was compared between the PACS and control groups. The correlation between iris curvature and central anterior chamber depth, anterior chamber volume and peripheral anterior chamber depth at 6 mm in the PACS group were analyzed. The correlation between changes in iris curvature and central anterior chamber depth, anterior chamber volume, and 6 mm peripheral anterior chamber depth before and after LPI treatment were also analyzed. A paired t test, independent t test and Pearson correlation coefficient were used for statistical analysis. \u0000 \u0000 \u0000Results: \u0000The coefficient of variation of anterior segment image capturing was 3.02%. The coefficient of variation of anterior segment image measurement was 2.54%. The radius of the iris curvature in the PACS group was 7.81±1.63 mm, which increased to 9.20±2.22 mm after LPI (t=-9.45, P<0.001). The radius of the iris curvature in the control group was 9.99±4.00 mm. The difference between the PACS group and control group was statistically significant (t=-5.69, P<0.001). After correction for the central anterior chamber depth, there was a correlation between the iris curvature radius in the direction of 0° (r=0.879, P<0.001), 90° (r=0.684, P=0.005), 180° (r=0.619, P=0.014), 270° (r=0.740, P=0.002) and the peripheral anterior chamber depth at 6 mm in the corresponding directions. After the treatment with LPI, except for the direction of 270° (r=0.453, P=0.078), there was a correlation between the changes in iris curvature in the direction of 0° (r=0.693, P=0.003), 90° (r=0.560, P=0.024), 180° (r=0.580, P=0.019) and the changes in peripheral anterior chamber depth at 6 mm in the corresponding directions. \u0000 \u0000 \u0000Conclusions: \u0000This quantitative measurement of iris curvature has good accuracy and repeatability. It can be used for the early diagnosis and quantitative evaluation of the therapeutic effect of PACS. \u0000 \u0000 \u0000Key words: \u0000iris curvature; quantitative measurement; primary angle closure suspect","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"21 1","pages":"14-19"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89223720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}