Solange Parra-Soto, Felipe Poblete-Valderrama, Alex Garrido, Yeny Concha-Cisternas, Cristian Álvarez, Igor Cigarroa, Ximena Díaz-Martínez, Fanny Petermann-Rocha, Carlos Celis-Morales, Jaime Vásquez-Gómez
{"title":"[Cardiorespiratory fitness in Chilean cancer patients: A comparative Analysis].","authors":"Solange Parra-Soto, Felipe Poblete-Valderrama, Alex Garrido, Yeny Concha-Cisternas, Cristian Álvarez, Igor Cigarroa, Ximena Díaz-Martínez, Fanny Petermann-Rocha, Carlos Celis-Morales, Jaime Vásquez-Gómez","doi":"10.4067/s0034-98872023000901115","DOIUrl":"https://doi.org/10.4067/s0034-98872023000901115","url":null,"abstract":"<p><strong>Introduction: </strong>Physical activity and cardiorespiratory fitness (CRF) are protective factors in cancer development. However, the CRF in the Chilean population diagnosed with cancer is unknown. This study aimed to evaluate the association that the CRF had between people with and without a cancer diagnosis and, secondarily, to compare the trend of the CRF according to years of cancer diagnosis in the Chilean population.</p><p><strong>Methods: </strong>Data from 5,483 people from the 2016-2017 National Health Survey between 15 and 98 years old were analyzed. Cancer diagnosis (all available) was determined with standardized questions, and CRF was calculated with an abbreviated method (demographics, anthropometry, lifestyles). Linear regression analysis adjusted for confounding variables was performed with the complex sample analysis module of the STATA v.16 program (95% CI, p < 0.05).</p><p><strong>Results: </strong>People with some cancer diagnosis versus those without cancer had a lower FCR level (ft: -1.23 [95% CI: -1.52; -0.94]). When comparing CRF levels according to cancer type, similar results were observed for colorectal, breast, and uterine cancer (p < 0.001) but not for thyroid cancer (p = 0.253). There was lower CRF from the first year of diagnosis of all types of cancer to over ten years, although not significant (p = 0.109).</p><p><strong>Conclusions: </strong>Those diagnosed with cancer presented lower CRF compared to those not diagnosed. In addition, in people with cancer, the CRF decreased with increasing years since the first diagnosis. It would be essential to evaluate and increase CRF in cancer patients.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rienzi Díaz-Navarro, Tamara Sáez, Felipe Peirano, Danilo Silva González
{"title":"[Saved myocardium in acute ST-segment elevation myocardial infarction post-reperfusion: Analysis by cardiac magnetic resonance].","authors":"Rienzi Díaz-Navarro, Tamara Sáez, Felipe Peirano, Danilo Silva González","doi":"10.4067/s0034-98872023000901164","DOIUrl":"https://doi.org/10.4067/s0034-98872023000901164","url":null,"abstract":"<p><strong>Objective: </strong>To quantify by cardiovascular magnetic resonance the salvaged myocardium in the myocardium supplied by the infarct-related artery in reperfused and non-reperfused patients with a first ST-segment elevation myocardial infarction (STEMI).</p><p><strong>Patients and method: </strong>Twenty-five patients with a first STEMI (non-reperfused, ten patients; thrombolysis, ten patients; primary angioplasty, five patients) underwent cardiac magnetic resonance imaging 3 to 6 days after coronary angiography. Myocardial salvage and myocardial salvage index were quantified.</p><p><strong>Results: </strong>Peak troponin values were lower in patients with primary angioplasty than in thrombolysis and non-reperfused patients (14,1 ng/ mL versus 515,4 ng/mL and 123,1 ng/mL, respectively; p < 0,007) and smaller infarct size (14,1 g versus 31,2 g and 31,5 g, respectively; p < 0,003). Myocardial salvage mass and myocardial salvage index were higher in patients with primary angioplasty than in thrombolysis and non-reperfused patients (27,4 g versus 4,7 g and 2,1 g, respectively; p < 0,003) and (65,2% versus 14,9% and 6,6%, respectively; p < 0,0001).</p><p><strong>Conclusions: </strong>The results of this study indicate the need to reassess the performance of coronary angioplasty and stent implantation in patients with a first STEMI, thrombolysis, and non-thrombolysis without prior myocardial viability studies. Cardiac magnetic resonance allows the quantification of salvaged myocardium and could be considered an emerging clinical application for the early evaluation of myocardial viability.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical features of blastic plasmacytoid dendritic neoplasm in Chile: report of 10 cases].","authors":"Vicente Micolich, Camila Peña, Fernanda Figueroa, Vania Briones, Catalina Vidal, Mauricio Chandia","doi":"10.4067/s0034-98872023000901201","DOIUrl":"https://doi.org/10.4067/s0034-98872023000901201","url":null,"abstract":"<p><strong>Background: </strong>Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare malignant tumor with a dismal prognosis, with isolated case reports in Chile. The BPDCN can present skin and bone marrow compromise, and its diagnosis is frequently confused with other pathologies. This study aimed to evaluate the clinical and immunophenotypical features of BPDCN in the Chilean population.</p><p><strong>Methods: </strong>We performed a retrospective study from 2013 to 2021 in clinical records of 2 public Chilean referral hospitals, including ten patients, 80% male, with a median age of 66 years (15-81).</p><p><strong>Results: </strong>The most frequent initial referral diagnoses were T-cell lymphoma (4/10) and acute myeloblastic leukemia (3/10). Seven patients presented skin and bone marrow involvement; we found a lower frequency of adenopathies (5/10), splenomegaly (2/10), and hepatomegaly (2/10). The complete blood count revealed anemia and leukopenia, with blasts in 5/10. Nine patients received induction therapy. CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) was indicated in 8/10 cases with remission in 5/8, and 1 patient received HyerCVAD (cyclophosphamide, vincristine, doxorubicin and dexamethasone, methotrexate, cytarabine) and an allogeneic bone marrow transplant. The median survival was 10 months (95% CI 4.2-15.8 months) with 9/10 deaths. Relapse in the central nervous system was documented in 2 cases.</p><p><strong>Conclusions: </strong>Our study found that BPDCN, a rare pathology in the Chilean population, shows a similar clinical presentation compared to previous studies. It is susceptible to respond to initial systemic and intrathecal chemotherapy.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximiliano Vergara, Nicolás Triantafilo, James Campbell, María José García, Patricio Rojas, Vicente Sandoval, Mauricio Sarmiento M, Mauricio Ocqueteau M
{"title":"[Decade of Hodgkin lymphoma: PET CT vs biopsy in single Academic Chilean Center].","authors":"Maximiliano Vergara, Nicolás Triantafilo, James Campbell, María José García, Patricio Rojas, Vicente Sandoval, Mauricio Sarmiento M, Mauricio Ocqueteau M","doi":"10.4067/s0034-98872023000800992","DOIUrl":"https://doi.org/10.4067/s0034-98872023000800992","url":null,"abstract":"<p><strong>Introduction: </strong>Hodgkin Lymphoma (HL) is a prevalent hematological cancer in the world and Chile.</p><p><strong>Objectives: </strong>Show the experience of 10 years treating HL in a Chilean academic center. Additionally, it exposes the diagnostic performance of PET CT and Bone Marrow Biopsy.</p><p><strong>Material and methods: </strong>We conducted a retrospective cohort study to collect data and outcomes of patients treated in our center.</p><p><strong>Results: </strong>82 patients were analyzed (Average age, 35 years old; the ratio between men and women was 1.9:1). Progression-free survival was 88.6% and 66.4% for localized and advanced stages, respectively. PET as a staging strategy had better sensitivity than Marrow Biopsy.</p><p><strong>Conclusions: </strong>The clinical results of the patients treated in this Chilean teaching center were comparable to the international literature. Additionally, PET CT proved to be a superior tool in diagnosis and staging compared to biopsy in our patients.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Food consumption frequency in schoolaged adolescents and its cardiovascular risk association].","authors":"Luz Miryam Tobón Borrero, Claudia Inés Navarro Toro, Claudia María Pinzón Gutiérrez","doi":"10.4067/s0034-98872023000801019","DOIUrl":"https://doi.org/10.4067/s0034-98872023000801019","url":null,"abstract":"<p><strong>Background: </strong>Childhood and adolescence are the life stages where eating habits related to the development of cardiovascular risk factors are usually established.</p><p><strong>Objective: </strong>To classify cardiovascular risk in school adolescents from Villavicencio (Colombia) and, additionally, to estimate its association with food intake frequency according to food kind.</p><p><strong>Methodology: </strong>This is an analytical cross-sectional study developed in 1,504 adolescents of 13 to 17 years of age schooling in Villavicencio. We evaluated the cardiovascular risk according to the model proposed by Rodríguez-Soriano and Sanjurjo, and the food intake frequency with a structured survey. We used a binomial regression model to estimate the relationship between cardiovascular risk and food intake frequency.</p><p><strong>Results: </strong>The mean age of the participants was 14.9 ± 0,07 years; 61.9% were women, and 80.6% came from schools located in urban areas. According to the cardiovascular risk classification, 34.5% of adolescents had a high cardiovascular risk, while 25.4% had intermediate risk. Men and those who consume more than two sugary drinks per day are those who presented a higher percentage of high cardiovascular risk (48.6% and 36.9%, respectively). Regression models showed that consumption of more than one sugary drink per day was associated with high levels of cardiovascular risk in adolescents (OR 1.27 95%CI 1.04-1.55).</p><p><strong>Conclusion: </strong>A high proportion of adolescents have medium and high cardiovascular risk; additionally, the consumption ofsugary drinks showed its association with cardiovascular risk.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia Bello-Escamilla, Carmen Gloria Bezanilla Collell, Cristián Tabillo García, María José Letelier
{"title":"[Profile of people served through telemedicine by the diabetes unit of a digital hospital in Chile].","authors":"Natalia Bello-Escamilla, Carmen Gloria Bezanilla Collell, Cristián Tabillo García, María José Letelier","doi":"10.4067/s0034-98872023000800971","DOIUrl":"https://doi.org/10.4067/s0034-98872023000800971","url":null,"abstract":"<p><strong>Background: </strong>Traditionally, diabetes management has involved a face-to-face meeting between the doctor and the patient. However, incorporating new tools such as telemedicine into clinical practice may be beneficial for controlling this disease.</p><p><strong>Objective: </strong>To describe, according to sociodemographic and clinical characteristics, the people treated through telemedicine by the diabetes cell of the Digital Hospital in Chile.</p><p><strong>Material and method: </strong>descriptive study with secondary data of 1427 people from the clinical registry of the diabetes cell of the Digital Hospital. The analysis included percentages, measures of central tendency, and X2 or UMann-Whitney test (p-value < 0.05) to test for independence between gender strata.</p><p><strong>Results: </strong>61% of the people were women, and the median age was 62 years. About 65% presented arterial hypertension and/or dyslipidemia, almost 55% of adults presented obesity, and more than 90% did not perform physical activity. More than 80% use insulin, and just over 45% of adults have HbA1c > 10%. Approximately 20% presented retinopathy, 17% neuropathy, and 13% risk offoot ulceration. Almost 45% of those diagnosed with nephropathy had a prognosis of very high-risk chronic kidney disease.</p><p><strong>Conclusion: </strong>The people who are treated through telemedicine by the diabetes cell of the Digital Hospital are mostly women and older adults from Familiy Health Care Centres (CESFAM), who present comorbidities, use insulin, are sedentary, have malnutrition due to excess, deficient metabolic control and their main diabetic complication is retinopathy.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Factors associated with the perception of loneliness among older people living in the community].","authors":"Alejandra-Ximena Araya, Evelyn Iriarte","doi":"10.4067/s0034-98872023000801028","DOIUrl":"https://doi.org/10.4067/s0034-98872023000801028","url":null,"abstract":"<p><strong>Background: </strong>Chilean community-dwelling older people are a vulnerable population with a high risk of being self-perceived as lonely.</p><p><strong>Aim: </strong>To examine the factors associated with the self-perception of loneliness in a group of Chilean community-dwelling older people.</p><p><strong>Material and methods: </strong>Cross-sectional study design with 540 participants aged 65 years and above (72.20 ± 6.22). Measures for sociodemographic, health status, and integral geriatric assessment were assessed. Correlations and multiple linear regression models were conducted.</p><p><strong>Results: </strong>Factors such as low perception of social support in everyday situations or cases of emergency, experiencing high depressive symptoms, and perceiving a poor quality of life were significantly associated with a higher self-perception of loneliness.</p><p><strong>Discussion: </strong>Preventive strategies and age-appropriate psychosocial interventions to mitigate or reverse the impact of these factors may be essential to reduce the self-perception of loneliness and consequently improve older people's well-being.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Celis-Morales, Marcelo Villagrán, Lorena Mardones, María Adela Martínez-Sanguinetti, Ana María Leiva-Ordoñez, Fernanda Carrasco-Marín, Natalia Ulloa, Miquel Martorell, Nicole Lasserre-Laso, Ximena Díaz-Martinez, Igor Cigarroa, Yeny Concha-Cisternas, Claudia Troncoso-Pantoja, Fabian Lanuza, Jaime Vásquez-Gómez, Solange Parra-Soto, Fanny Petermann-Rocha
{"title":"[Effect of Sedentary behaviors on the Interaction Between the FTO Gene and Adiposity Levels in Chilean Adults - Results from the GENADIO Study].","authors":"Carlos Celis-Morales, Marcelo Villagrán, Lorena Mardones, María Adela Martínez-Sanguinetti, Ana María Leiva-Ordoñez, Fernanda Carrasco-Marín, Natalia Ulloa, Miquel Martorell, Nicole Lasserre-Laso, Ximena Díaz-Martinez, Igor Cigarroa, Yeny Concha-Cisternas, Claudia Troncoso-Pantoja, Fabian Lanuza, Jaime Vásquez-Gómez, Solange Parra-Soto, Fanny Petermann-Rocha","doi":"10.4067/s0034-98872023000800980","DOIUrl":"10.4067/s0034-98872023000800980","url":null,"abstract":"<p><strong>Background: </strong>The Fat-mass and obesity-associated-gene (FTO gene) and sedentary behavior time are associated with obesity. However, whether sedentary behavior time can modify the genetic predisposition to obesity in the Chilean population is unknown. Therefore, this study investigated the association between sedentary behavior, adiposity markers, and the FTO gene.</p><p><strong>Methods: </strong>This cross-sectional study included 409 participants from the Genes, Environment, Diabetes, and Obesity (GENADIO) study. Adiposity markers studied included body weight, body mass index (BMI), waist circumference (WC), and fat mass. Sedentary behaviors were measured using accelerometers. Using multiple regression, we evaluated the interaction between sedentary behaviors and the FTO gene (rs9939609) on adiposity markers.</p><p><strong>Results: </strong>Sedentary behaviors and the FTO genotype were positively associated with higher body weight, BMI, WC, and fat mass. However, the association between time of sedentary behavior and adiposity markers was higher in carriers of the risk variant for the FTO gene. For each hour of increment in sedentary behaviors, body weight increases by 1.36 kg ([95% CI: 0.27; 2.46], p = 0.015) and 2.95 kg ([95%CI: 1.24; 4.65], p = 0.001) in non-risk carriers (TT) versus risk carriers (AA), respectively. We observed similar results for WC, BMI, and body fat, but the interaction was significant only for WC.</p><p><strong>Conclusion: </strong>The association between sedentary behaviors and adiposity markers, especially body weight and WC, is higher in individuals who carry the risk variant of the FTO gene.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorena Gallardo-Peralta, Esteban Sánchez-Moreno, Vicente Rodríguez-Rodríguez, Abel Soto Higuera, Julio Tereucán Angulo, Lorena Valencia Galvez
{"title":"[Prevalence of loneliness among older people living in rural areas. Differences by ethnic group and predictor variables].","authors":"Lorena Gallardo-Peralta, Esteban Sánchez-Moreno, Vicente Rodríguez-Rodríguez, Abel Soto Higuera, Julio Tereucán Angulo, Lorena Valencia Galvez","doi":"10.4067/s0034-98872023000801010","DOIUrl":"https://doi.org/10.4067/s0034-98872023000801010","url":null,"abstract":"<p><strong>Background: </strong>Loneliness is one of the most recurrent public health problems in older people. However, there is little data available in Chile on its prevalence in people over 60 years of age living in rural areas and belonging to native or Afro-descendant groups.</p><p><strong>Aim: </strong>To examine the prevalence of loneliness among older people living in rural areas by ethnic group and to analyze the socio-demographic, family, and health variables related to loneliness.</p><p><strong>Methods: </strong>We interviewed 1,692 elderly people living in Chilean rural areas of the regions of Arica and Parinacota, Tarapacá, Antofagasta, Atacama, Coquimbo, Valparaíso, Los Lagos, Aisén and Magallanes. The instruments applied were the DJGLS-6 loneliness scale, Family-APGAR, questionnaire of 13 most frequent health problems in Chilean older people, and Barthel index.</p><p><strong>Results: </strong>We found a high prevalence of loneliness (over 55%) among Afro-descendants, Quechua, Atacameño, Colla, Chango, Huilliche, Kawesqar and non-indigenous people. Emotional loneliness is the most prevalent among indigenous and non-indigenous older people living in rural areas (≥ 71%). Variables associated with loneliness were being female, age, not having a partner, living alone, family dysfunctionality, and having health problems.</p><p><strong>Conclusions: </strong>Loneliness in rural areas is higher in older people, and this situation becomes more complex at the crossroads of ethnic-cultural diversity; it is necessary to continue to address this problem that affects biopsychosocial well-being in old age.</p>","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Place of death in chilean patients with advanced cancer: A retrospective cohort study].","authors":"Andrés Vargas, Pamela Turrillas","doi":"10.4067/s0034-98872023000801105","DOIUrl":"https://doi.org/10.4067/s0034-98872023000801105","url":null,"abstract":"","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}