Allergologie select最新文献

Occupational buckwheat allergy in a health food store employee: From inhalative exposure to anaphylaxis.

Allergologie select Pub Date : 2025-03-28 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02561E

Julia Felicitas Pilz, Valentina Faihs, Claudia Kugler, Ulf Darsow, Tilo Biedermann, Knut Brockow

引用次数: 0

Recent findings from the anaphylaxis registry: Where are we, where do we want to go?

Allergologie select Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02529E

Margitta Worm, Sabine Dölle-Bierke, Lea Faust, Veronika Höfer

{"title":"Recent findings from the anaphylaxis registry: Where are we, where do we want to go?","authors":"Margitta Worm, Sabine Dölle-Bierke, Lea Faust, Veronika Höfer","doi":"10.5414/ALX02529E","DOIUrl":"10.5414/ALX02529E","url":null,"abstract":"The anaphylaxis registry collects structured data across Europe regarding elicitors, accompanying circumstances and other diseases as well as the treatment of severe allergic reactions. By March 2024, 16,988 cases had been registered, of which ~ 1/3 were children and 2/3 were adults. Among children, boys are most frequent affected, while among adults, women are most frequently affected. The most common elicitors depend on age and continue to be dominated by the food allergens in children and by insect venom in adults. The occurrence of anaphylaxis without skin symptoms is not uncommon and occurs in children in the range of 5%, regardless of the trigger, while in adults the frequency is generally higher (up to 15%) and there are trigger-dependent differences. The analysis of the rare food allergens that trigger anaphylaxis shows, for example, spices such as saffron and sumac and vegetables such as chicory or spring onions. One case was elicited by a mealworm. Food shows an increase in triggering anaphylaxis in children. The trigger spectrum of foods is large and relevant due to the increasing plant-based diets. Rare allergens can cause anaphylaxis and should be further considered and monitored in the coming years to determine their frequency as triggers of severe reactions.","PeriodicalId":101298,"journal":{"name":"Allergologie select","volume":"9 ","pages":"21-27"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on Reese et al. 2023 "Vegan Diets from an Allergy Point of View - Position Paper of the DGAKI Working Group on Food Allergy". Allergologie Select. 2023; 7: 57-83. 对 Reese 等人 2023 年 "从过敏角度看素食--DGAKI 食物过敏工作组的立场文件 "的评论。Allergologie Select.2023; 7: 57-83.

Allergologie select Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02572E

Christian Koeder

引用次数: 0

Recommendations on how to proceed in case of suspected allergy to penicillin/β-lactam antibiotics: Position paper of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Society for Pediatric Allergology (GPA), Austrian Society for Allergology and Immunology (ÖGAI) and the Swiss Society for Allergology and Immunology (SGAI).

Allergologie select Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02531E

Knut Brockow, Wolfgang Pfützner, Bettina Wedi, Gerda Wurpts, Axel Trautmann, Burkhard Kreft, Timo Buhl, Mathias Sulk, Andreas Recke, Kathrin Scherer, Stefan Wöhrl, Irena Neustädter, Regina Treudler, Christiane Querbach, Margitta Worm

{"title":"Recommendations on how to proceed in case of suspected allergy to penicillin/β-lactam antibiotics: Position paper of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Society for Pediatric Allergology (GPA), Austrian Society for Allergology and Immunology (ÖGAI) and the Swiss Society for Allergology and Immunology (SGAI).","authors":"Knut Brockow, Wolfgang Pfützner, Bettina Wedi, Gerda Wurpts, Axel Trautmann, Burkhard Kreft, Timo Buhl, Mathias Sulk, Andreas Recke, Kathrin Scherer, Stefan Wöhrl, Irena Neustädter, Regina Treudler, Christiane Querbach, Margitta Worm","doi":"10.5414/ALX02531E","DOIUrl":"10.5414/ALX02531E","url":null,"abstract":"β-lactam antibiotics (BLAs) are still the antibiotics of first choice for the treatment of many bacterial infections. Treatment with a BLA is often hindered by a suspected allergy, up to 10% of the population report an allergy to penicillin. After allergological evaluation of the suspected allergic reaction to a BLA, most patients show a low probability of a BLA allergy; only in a minority of cases an allergic reaction to the repeated administration of a BLA appear likely in view of the previous history. In > 90% of cases, the suspected BLA allergy can be ruled out by allergy diagnostics. We recommend a risk-stratified approach in the context of an urgent need for BLA, which should enable most patients to receive a BLA therapy. After acute therapy, allergy diagnostics have to be done to clearly prove or reliably rule out a BLA allergy.","PeriodicalId":101298,"journal":{"name":"Allergologie select","volume":"9 ","pages":"28-39"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The importance of registries in clinical practice: Insights from the national atopic dermatitis registry TREATgermany.

Allergologie select Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02545E

Tatjana Honstein, Barbara Kind, Dora Stölzl, Inken Harder, Sigrid Müller, Thomas Birkner, Luise Heinrich, Sascha Fischer, Nicole Sander, Annice Heratizadeh, Jochen Schmitt, Stephan Weidinger, Thomas Werfel

{"title":"The importance of registries in clinical practice: Insights from the national atopic dermatitis registry TREATgermany.","authors":"Tatjana Honstein, Barbara Kind, Dora Stölzl, Inken Harder, Sigrid Müller, Thomas Birkner, Luise Heinrich, Sascha Fischer, Nicole Sander, Annice Heratizadeh, Jochen Schmitt, Stephan Weidinger, Thomas Werfel","doi":"10.5414/ALX02545E","DOIUrl":"10.5414/ALX02545E","url":null,"abstract":"Atopic dermatitis (AD) is an inflammatory, multifactorial skin disease characterized by eczematous skin lesions, severe itching, and serious limitations in quality of life. Since 2016, TREATgermany has been a national clinical registry for patients with moderate to severe AD with around 2,550 participating patients, enabling the collection of physical, patient-reported social and psychological data as well as the collection of biosamples in routine care. TREATgermany is one of the largest academically managed AD registries in the world. This current review summarizes a selection of published analyses from registry data from TREATgermany, which retrospectively identified important correlations with regard to treatment response and safety, and investigated quality of life, performance, and mental health under everyday conditions. In addition, initial molecular signatures were identified from the blood and skin samples obtained from the patients included in the registry, which may be useful as prognostic markers.","PeriodicalId":101298,"journal":{"name":"Allergologie select","volume":"9 ","pages":"40-46"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Letter to the Editor from Christian Koeder .

Allergologie select Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02573E

Imke Reese, Christiane Schäfer, Barbara Ballmer-Weber, Kirsten Beyer, Sabine Dölle-Bierke, Suzanne van Dullemen, Uta Jappe, Sabine Schnadt, Regina Treudler

引用次数: 0

Substantial psychosocial impairments in patients with chronic urticaria are associated with delayed referral to urticaria centers, non-academic treatments, and dietary changes.

Allergologie select Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02554E

Julia Zarnowski, Paula Kage, Regina Treudler

{"title":"Substantial psychosocial impairments in patients with chronic urticaria are associated with delayed referral to urticaria centers, non-academic treatments, and dietary changes.","authors":"Julia Zarnowski, Paula Kage, Regina Treudler","doi":"10.5414/ALX02554E","DOIUrl":"10.5414/ALX02554E","url":null,"abstract":"Background: Chronic idiopathic urticaria (CIU) is common in allergological practice. Although therapeutic options have improved in the past decade, patients still suffer from a significant burden of disease and are often treated insufficiently.Objective: We aimed at analyzing the psychiatric comorbidities, social impairments, and treatment gap in a real-world setting.Materials and methods: Adult patients with CIU were investigated for demographical data, medical history, and psychosocial burden. Validated questionnaires were used to assess urticaria activity, control of disease, quality-of-life impairment, and psychiatric comorbidities.Results: 82 patients (78% female; 47.5 ± 14.8 years) were included. 65.9% had insufficient disease control, 11% reported on prior self-medication with drugs, 19.5% were seeking help from non-academic medicine, and 54.9% tried a change of diet. The use of non-academic treatment was significantly associated with higher disease activity. Self-initiated dietary changes were significantly associated with less control of disease. Delayed referrals to a urticaria-specialized center were significantly linked to self-reported psychiatric diseases, self-medication with drugs and self-initiated dietary changes.Conclusion: Our data show an unsatisfactory control of CIU in many patients and substantial psychosocial impairments which are also associated with a delayed referral to urticaria centers, self-initiated non-academic treatments, and dietary changes.","PeriodicalId":101298,"journal":{"name":"Allergologie select","volume":"9 ","pages":"8-15"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Significant handling errors and education gaps regarding the use of the emergency kit among adult patients with Hymenoptera venom allergy.

Allergologie select Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI: 10.5414/ALX02476E

Julia Zarnowski, Louise Wilkens, Regina Treudler

{"title":"Significant handling errors and education gaps regarding the use of the emergency kit among adult patients with Hymenoptera venom allergy.","authors":"Julia Zarnowski, Louise Wilkens, Regina Treudler","doi":"10.5414/ALX02476E","DOIUrl":"https://doi.org/10.5414/ALX02476E","url":null,"abstract":"Aim: In case of systemic anaphylactic reactions after Hymenoptera stings, patients should be provided with an adrenaline autoinjector (AAI). We aimed to evaluate the education and handling competence of patients in a real-world setting.Materials and methods: Patients with Hymenoptera venom allergy presenting for the first time in our clinic with a previously prescribed emergency kit including an AAI were interviewed using a standardized questionnaire and were asked to demonstrate the AAI use with a dummy.Results: 82 patients (62.2% female, mean age 52.0 ± 17.3 years) with allergy to wasp venom (85.3%), bee venom (9.8%), or hornet venom (4.9%) were included. 37.8% reported to have received a practical training on the AAI upon prescription. 59.8% of all patients showed significant handling errors which would have led to misinjections in 30.6%.Conclusion: Our data demonstrate a considerable lack of education, significant handling errors of the emergency kit, and a high risk of misinjections of the AAI. As the emergency kit is potentially lifesaving, the awareness for a sufficient education and training needs to be risen.","PeriodicalId":101298,"journal":{"name":"Allergologie select","volume":"9 ","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitization to food allergens is associated with more severe wheezing in children. 对食物过敏原的敏感与儿童更严重的喘息有关。

Allergologie select Pub Date : 2024-12-31 eCollection Date: 2024-01-01 DOI: 10.5414/ALX02546E

Ozge Yılmaz, Cecilia M Patino, Fatma Taneli, Esra Toprak Kanik, Ahmet Turkeli, Ceyhun Gozukara, Sezen Irmak, Hasan Yuksel

{"title":"Sensitization to food allergens is associated with more severe wheezing in children.","authors":"Ozge Yılmaz, Cecilia M Patino, Fatma Taneli, Esra Toprak Kanik, Ahmet Turkeli, Ceyhun Gozukara, Sezen Irmak, Hasan Yuksel","doi":"10.5414/ALX02546E","DOIUrl":"https://doi.org/10.5414/ALX02546E","url":null,"abstract":"Aims: We investigated sensitization to food allergens as a prognostic factor for wheezing in children with recurrent wheezing and compared serum club cell 16 (CC16) and surfactant protein D (SP-D) among these children with and without sensitization to food allergens.Materials and methods: Children with recurrent wheezing were enrolled in this prospective cohort study. Specific IgE to five common food allergens (Fx5) was assessed at baseline, and children were followed-up for 1 year for new-onset wheezing episodes. Baseline wheezing severity score, CC16, and SP-D levels were measured.Results: We enrolled 295 children (44 Fx5(+)). Poisson regression analysis revealed that Fx5 positivity changed the yearly frequency of wheeze by a factor of 1.66 (p = 0.05, 95% CI: (0.99 - 2.75)). Levels of CC16 and SP-D were not significantly different between the groups (p = 0.679 and p = 0.988).Conclusion: Sensitization to food allergens irrespective of food associated clinical allergy findings is associated with worse prognosis of wheezing in children.","PeriodicalId":101298,"journal":{"name":"Allergologie select","volume":"8 ","pages":"434-441"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142961079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Registries in allergy: Structure, target groups, and key findings of allergy-focused registries in Germany. 过敏登记：结构、目标群体和德国过敏登记的主要发现。

Allergologie select Pub Date : 2024-12-31 eCollection Date: 2024-01-01 DOI: 10.5414/ALX02536E

Marie Farkic, Philipp Globig, Aikaterina Alexiou, Margitta Worm

引用次数: 0