Revista Brasileira de Reumatologia (English Edition)最新文献

{"title":"Impacts of social support on symptoms in Brazilian women with fibromyalgia","authors":"Rodrigo Pegado de Abreu Freitas ,&nbsp;Sandra Cristina de Andrade ,&nbsp;Maria Helena Constantino Spyrides ,&nbsp;Maria Thereza Albuquerque Barbosa Cabral Micussi ,&nbsp;Maria Bernardete Cordeiro de Sousa","doi":"10.1016/j.rbre.2016.07.001","DOIUrl":"10.1016/j.rbre.2016.07.001","url":null,"abstract":"<div><p>We aimed to assess the impact of social support on symptoms in Brazilian women with FM. An observational, descriptive study enrolling 66 women who met the 1990 American College of Rheumatology (ACR) criteria. Social support was measured by the Social Support Survey (MOS-SSS), functionality was evaluated using the Fibromyalgia Impact Questionnaire (FIQ), depression was assessed using the Beck Depression Inventory (BDI), anxiety was measured using the Hamilton Anxiety Scale (HAS), affectivity was measured by Positive and Negative Affect Schedule (PANAS), and algometry was carried out to record pressure pain threshold (PPth) and tolerance (PPTo) at 18 points recommended by the ACR. Patients were divided into normal (NSS) or poor social support (PSS) groups with PSS defined as having a MOS-SSS score below the 25th percentile of the entire sample. Mann–Whitney or Unpaired <em>t</em>-test were used to compare intergroup variables and Fisher's for categorical variables. Analysis of covariance and Pearson correlation test were used. No differences in sociodemographic variables between PSS and NSS were found. Differences between NSS and PSS groups were observed for all four subcategories of social support and MOS-SSS total score. Significant differences between NSS and PSS on depression (<em>p</em> <!-->=<!--> <!-->0.007), negative affect (<em>p</em> <!-->=<!--> <!-->0.025) and PPTh (<em>p</em> <!-->=<!--> <!-->0.016) were found. Affectionate subcategory showed positive correlation between pain and positive affect in PSS. Positive social interaction subcategory showed a negative correlation between FIQ and depression state. Therefore social support appears to contribute to ameliorate mental and physical health in FM.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 197-203"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35020908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between demyelinating disease and autoimmune rheumatic disease in a pediatric population","authors":"Ana Luiza M. Amorim ,&nbsp;Nadia C. Cabral ,&nbsp;Fabiane M. Osaku ,&nbsp;Claudio A. Len ,&nbsp;Enedina M.L. Oliveira ,&nbsp;Maria Teresa Terreri","doi":"10.1016/j.rbre.2016.09.016","DOIUrl":"10.1016/j.rbre.2016.09.016","url":null,"abstract":"<div><h3>Introduction</h3><p>Multiple sclerosis (MS) and neuromyelitis optica (NMO) are demyelinating diseases of the central nervous system. Autoimmunity in patients with demyelinating disease and in their families has been broadly investigated and discussed. Recent studies show a higher incidence of rheumatic autoimmune diseases among adult patients with MS or NMO and their families, but there are no studies in the pediatric population.</p></div><div><h3>Objective</h3><p>To evaluate an association of MS and NMO with autoimmune rheumatic diseases in pediatric patients.</p></div><div><h3>Method</h3><p>22 patients younger than 21 years old with MS or NMO diagnosed before the age of 18 years were evaluated regarding epidemiological data, clinical presentation, association with autoimmune diseases, family history of autoimmune diseases, laboratory findings, imaging studies and presence of auto-antibodies.</p></div><div><h3>Results</h3><p>Among the patients studied, there was a prevalence of females (68.1%). The mean age of symptoms onset was 8 years and 9 months and the mean current age was 16 years and 4 months. Two patients (9%) had a history of associated autoimmune rheumatic disease: one case of juvenile dermatomyositis in a patient with NMO and another of systemic lupus erythematosus in a patient with MS. Three patients (13%) had a family history of autoimmunity in first-degree relatives. Antinuclear antibody was found positive in 80% of patients with NMO and 52% of patients with MS. About 15% of antinuclear antibody-positive patients were diagnosed with rheumatologic autoimmune diseases.</p></div><div><h3>Conclusion</h3><p>Among patients with demyelinating diseases diagnosed in childhood included in this study there was a high frequency of antinuclear antibody positivity but a lower association with rheumatologic autoimmune diseases than that observed in studies conducted in adults.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 224-228"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.09.016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35020913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Independence of carbohydrate-deficient isoforms of transferrin and cyclic citrullinated peptides in rheumatoid arthritis","authors":"Monika Gudowska ,&nbsp;Ewa Gindzienska-Sieskiewicz ,&nbsp;Ewa Gruszewska ,&nbsp;Bogdan Cylwik ,&nbsp;Stanislaw Sierakowski ,&nbsp;Maciej Szmitkowski ,&nbsp;Lech Chrostek","doi":"10.1016/j.rbre.2016.01.005","DOIUrl":"10.1016/j.rbre.2016.01.005","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this study was to assess the relationship between the two types of posttranslational modifications of proteins in RA: glycosylation on the example of carbohydrate-deficient transferrin and citrullination by means of autoantibodies to cyclic citrullinated peptides.</p></div><div><h3>Methods</h3><p>The study was carried out in 50 RA patients. CDT was measured using N Latex CDT immunonephelometric test, the results were presented in absolute and relative units. Anti-CCP were measured using the chemiluminescent method and rheumatoid factor by immunoturbidimetric method.</p></div><div><h3>Results</h3><p>80% of RA patients were positive for anti-CCP, 70% for RF and 62% for both, anti-CCP and RF. The level of %CDT was significantly elevated, but absolute CDT level was not changed. The mean absolute CDT concentration was higher in anti-CCP positive patients than that in anti-CCP negative. CDT (absolute and relative concentration) did not correlate with anti-CCP and RF. However, serum RF significantly correlated with anti-CCP. %CDT did not correlate with anti-CCP, but absolute level correlated with anti-CCP only in anti-CCP negative and RF negative patients. CDT did not correlate with RF, but solely with anti-CCP in anti-CCP negative patients. Anti-CCP correlated with DAS 28 only in anti-CCP negative RA, but CDT (absolute and relative units) correlated with DAS 28 in all patients and in anti-CCP positive RA.</p></div><div><h3>Conclusions</h3><p>These results suggest that the changes in CDT and anti-CCP concentrations are not associated with oneself and indicate on the independence of these posttranslational modifications in rheumatoid arthritis. Only the alterations in transferrin glycosylation reflected the activity of RA.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 185-189"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.01.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35022499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of periodontal treatment on rheumatoid arthritis: a systematic review and meta-analysis","authors":"Débora Cerqueira Calderaro ,&nbsp;Jôice Dias Corrêa ,&nbsp;Gilda Aparecida Ferreira ,&nbsp;Izabela Guimarães Barbosa ,&nbsp;Carolina Castro Martins ,&nbsp;Tarcília Aparecida Silva ,&nbsp;Antônio Lúcio Teixeira","doi":"10.1016/j.rbre.2016.11.011","DOIUrl":"10.1016/j.rbre.2016.11.011","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the influence of periodontal treatment on rheumatoid arthritis activity.</p></div><div><h3>Methods</h3><p>MEDLINE/PUBMED, The Cochrane Library, Clinical Trials, SciELO and LILACS were searched for studies published until December 2014. Included articles were: prospective studies; including patients older than 18 years, diagnosed with periodontitis and rheumatoid arthritis submitted to non-surgical periodontal treatment; with a control group receiving no periodontal treatment; with outcomes including at least one marker of rheumatoid arthritis activity. Methodological quality of the studies was assessed using PEDro scale. Quantitative data were pooled in statistical meta-analysis using Review Manager 5.</p></div><div><h3>Results</h3><p>Four articles were included. Non-surgical periodontal treatment was associated with a significant reduction of DAS28 (OR: −1.18; 95% CI: −1.43, −0.93; <em>p</em> <!-->&lt;<!--> <!-->0.00001). Erythrocyte sedimentation rate, C-reactive protein, patient's assessment of rheumatoid activity using visual analogical scale, tender and swollen joint counts showed a trend toward reduction (not statistically significant).</p></div><div><h3>Conclusions</h3><p>The reduction of DAS 28 in patients with rheumatoid arthritis after periodontal treatment suggests that the improvement of periodontal condition is beneficial to these patients. Further randomized controlled clinical trials are necessary to confirm this finding.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 238-244"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.11.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35020914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of rheumatoid arthritis in the public health system in Santa Catarina, Brazil: a descriptive and temporal trend analysis from 1996 to 2009","authors":"Rafael Kmiliauskis Santos Gomes ,&nbsp;Fabio Antero Pires ,&nbsp;Moacyr Roberto Cuce Nobre ,&nbsp;Mauricio Felippi de Sá Marchi ,&nbsp;Jennifer Cristina Kozechen Rickli","doi":"10.1016/j.rbre.2016.07.003","DOIUrl":"10.1016/j.rbre.2016.07.003","url":null,"abstract":"<div><h3>Introduction</h3><p>There are few studies that carried out a descriptive and trend analysis based on available data from the Unified Health System (SUS) between pre- and post-free dispensing of pharmacological treatment of rheumatoid arthritis (RA) from the perspective of the public health system, in terms of the direct cost of the disease among adults and elderly residents of the State of Santa Catarina, Brazil. This study aims to characterize the direct cost of medical and surgical procedures before and after the dispensing of drugs in this state.</p></div><div><h3>Methods</h3><p>This is a time series-type study with a cross-sectional survey of data from the Hospital (SIH) and Outpatient (SIA) Information System of SUS during the period from 1996 to 2009.</p></div><div><h3>Results</h3><p>Between 1996 and 2009, the total expenditure for hospital- and outpatient pharmacological treatment of rheumatoid arthritis was R$ 26,659,127.20. After the dispensing of drug treatment by SUS a decrease of 36% in the number of hospital admissions was observed; however, an increase of 19% in clinical procedures was noted.</p></div><div><h3>Conclusion</h3><p>During the observed period, a reduction in the number of hospital admissions for both clinical and orthopedic surgical procedures related to this disease was observed. Nevertheless, there was an increase in the cost of medical admissions.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 204-209"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35020909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possible links between osteoporosis and periodontal disease","authors":"Daniela Cia Penoni ,&nbsp;Anna Thereza Thomé Leão ,&nbsp;Tatiana Melo Fernandes ,&nbsp;Sandra Regina Torres","doi":"10.1016/j.rbre.2016.03.004","DOIUrl":"10.1016/j.rbre.2016.03.004","url":null,"abstract":"","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 270-273"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35021355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadequate pain relief among patients with primary knee osteoarthritis","authors":"Pedro A. Laires ,&nbsp;Jorge Laíns ,&nbsp;Luís C. Miranda ,&nbsp;Rui Cernadas ,&nbsp;Srini Rajagopalan ,&nbsp;Stephanie D. Taylor ,&nbsp;José C. Silva","doi":"10.1016/j.rbre.2016.11.005","DOIUrl":"10.1016/j.rbre.2016.11.005","url":null,"abstract":"<div><h3>Background</h3><p>Despite the widespread treatments for osteoarthritis (OA), data on treatment patterns, adequacy of pain relief, and quality of life are limited. The prospective multinational Survey of Osteoarthritis Real World Therapies (SORT) was designed to investigate these aspects.</p></div><div><h3>Objectives</h3><p>To analyze the characteristics and the patient reported outcomes of the Portuguese dataset of SORT at the start of observation.</p></div><div><h3>Methods</h3><p>Patients ≥50 years with primary knee OA who were receiving oral or topical analgesics were eligible. Patients were enrolled from seven healthcare centers in Portugal between January and December 2011. Pain and function were evaluated using the Brief Pain Inventory (BPI) and WOMAC. Quality of life was assessed using the 12-Item Short Form Health Survey (SF-12). Inadequate pain relief (IPR) was defined as a score &gt;4/10 on item 5 of the BPI.</p></div><div><h3>Results</h3><p>Overall, 197 patients were analyzed. The median age was 67.0 years and 78.2% were female. Mean duration of knee OA was 6.2 years. IPR was reported by 51.3% of patients. Female gender (adjusted odds ratio – OR 2.15 [95%CI 1.1, 4.5]), diabetes (OR 3.1 [95%CI 1.3, 7.7]) and depression (OR 2.24 [95%CI 1.2, 4.3]) were associated with higher risk of IPR. Patients with IPR reported worst outcomes in all dimensions of WOMAC (<em>p</em> <!-->&lt;<!--> <!-->0.001) and in all eight domains and summary components of SF-12 (<em>p</em> <!-->&lt;<!--> <!-->0.001).</p></div><div><h3>Conclusions</h3><p>Our findings indicate that improvements are needed in the management of pain in knee OA in order to achieve better outcomes in terms of pain relief, function and quality of life.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 229-237"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.11.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35020912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical course of Behcet's disease in a patient with delayed diagnosis and radiological follow-up of the thrombi with computed tomography angiography: a five-year follow-up under immunosuppressive treatment","authors":"Muhammet Cinar ,&nbsp;Sedat Yilmaz ,&nbsp;Sinan Akay ,&nbsp;Ugur Bozlar ,&nbsp;Ayhan Dinc","doi":"10.1016/j.rbre.2013.08.004","DOIUrl":"10.1016/j.rbre.2013.08.004","url":null,"abstract":"","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 264-269"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2013.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35021353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of the Lower Extremity Functional Scale (LEFS-Brazil) questionnaire compared to Lequesne Algofunctional Index for definition of knee and hip osteoarthritis severity","authors":"João Paulo M. Santos ,&nbsp;Rubens A. da Silva ,&nbsp;Marcos Tadeu P. Fernandes ,&nbsp;Regina Célia Poli-Frederico ,&nbsp;Denis C. Santos ,&nbsp;Rodrigo A.C. Andraus ,&nbsp;Thais Maria F. Fernandes ,&nbsp;Karen B.P. Fernandes","doi":"10.1016/j.rbre.2016.07.010","DOIUrl":"10.1016/j.rbre.2016.07.010","url":null,"abstract":"","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 274-277"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.07.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35021356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unbalanced expression of aryl hydrocarbon receptor in peripheral blood CCR6+CD4+ and CD4+CD25+T cells of rheumatoid arthritis","authors":"Lin Cheng ,&nbsp;Long Qian ,&nbsp;Yue Tan ,&nbsp;Guo-Sheng Wang ,&nbsp;Xiao-Mei Li ,&nbsp;Xiang-Pei Li ,&nbsp;Chao-Yin Luo","doi":"10.1016/j.rbre.2016.07.002","DOIUrl":"10.1016/j.rbre.2016.07.002","url":null,"abstract":"<div><h3>Objective</h3><p>The goal of this study was to analyze the role of aryl hydrocarbon receptor in peripheral blood CCR6⁺CD4⁺ and CD4⁺CD25⁺T cells of patients with rheumatoid arthritis.</p></div><div><h3>Methods</h3><p>Flow cytometry was applied to determine the proportion of AhR positive cells in CCR6⁺CD4⁺T, CD4⁺CD25⁺T and peripheral blood peripheral mononuclear cells from each subject. AhR mRNA and CYP1A1 mRNA relative expression levels were tested by real-time PCR.</p></div><div><h3>Results</h3><p>The percentage of AhR positive cells in peripheral blood mononuclear cells was higher in RA group than that in healthy cases [(35.23<!--> <!-->±<!--> <!-->10.71)% <em>vs.</em> (18.83<!--> <!-->±<!--> <!-->7.32)%, <em>p</em> <!-->&lt;<!--> <!-->0.01]. The expression levels of AhR and CYP1A1 were both increased in patients with RA while compared to controls [(3.71<!--> <!-->±<!--> <!-->1.63) <em>vs.</em> (2.00<!--> <!-->±<!--> <!-->1.27), <em>p</em> <!-->=<!--> <!-->0.002; (2.62<!--> <!-->±<!--> <!-->2.08) <em>vs.</em> (0.62<!--> <!-->±<!--> <!-->0.29), <em>p</em> <!-->&lt;<!--> <!-->0.01, respectively]. In RA patients, the percentage of AhR positive cells in CD4⁺CD25⁺T cells was significantly lower than that from controls [17.90 (6.10<!--> <!-->±<!--> <!-->80.10)% <em>vs.</em> (52.49<!--> <!-->±<!--> <!-->19.18)%, <em>p</em> <!-->&lt;<!--> <!-->0.01]; In healthy controls, the percentage of AhR positive cells in CD4⁺CD25⁺T cells was significantly higher than that in CCR6⁺CD4⁺T cells, and was also significantly higher than that in PBMCs [(52.49<!--> <!-->±<!--> <!-->19.18)% <em>vs.</em> (23.18<!--> <!-->±<!--> <!-->5.62)% <em>vs.</em> (18.06<!--> <!-->±<!--> <!-->7.80)%, <em>X</em>² <!-->=<!--> <!-->24.03, <em>p</em> <!-->&lt;<!--> <!-->0.01]; in RA patients, the percentage of AhR positive cells in CCR6⁺CD4⁺T cells was significantly increased than that in CD4⁺CD25⁺T cells and PBMCs [(46.02<!--> <!-->±<!--> <!-->14.68)% <em>vs.</em> 17.90 (6.10<!--> <!-->±<!--> <!-->80.10)% <em>vs.</em> (34.22<!--> <!-->±<!--> <!-->10.33)%, <em>X</em>² <!-->=<!--> <!-->38.29, <em>p</em> <!-->&lt;<!--> <!-->0.01]; Nevertheless, no statistically significant relationship was found between clinical data and AhR positive cells in CCR6⁺CD4⁺T and CD4⁺CD25⁺T cells.</p></div><div><h3>Conclusion</h3><p>AhR may participate in the pathological progress of RA by controlling the differentiation of Th17 and Treg cells in peripheral blood.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 3","pages":"Pages 190-196"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35022498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}