Chemical science transactions最新文献_第3页

Synthesis and Characterization of 2-Bromo-3-hydroxy-2-nitropropylcinnamate 2-溴-3-羟基-2-硝基丙基肉桂酸酯的合成与表征

Chemical science transactions Pub Date : 2019-10-30 DOI: 10.7598/cst2019.1705

引用次数: 0

Benzodioxole and 1,2,4-Oxadiazole Associated 1,2,3-Triazoles: Synthesis, Characterization and Evaluation as Antibacterial Agents 苯并二唑和1,2,4-恶二唑类1,2,3-三唑类抗菌药物的合成、表征及评价

Chemical science transactions Pub Date : 2019-10-30 DOI: 10.7598/cst2019.20190003

引用次数: 0

Electrochemical Behavior of Antidepressant Drug Vilazodone Hydrocholoride and its Determination at F-MWCNT-Nafion/GCE Sensor 抗抑郁药盐酸维拉唑酮的电化学行为及其在F-MWCNT-Nafion/GCE传感器上的测定

Chemical science transactions Pub Date : 2019-10-24 DOI: 10.7598/cst2019.1596

引用次数: 0

Synthesis, Characterization and Antioxidant Activity of Novel 3-(2,5-dioxo-imidazolidin-1-yl)-1,1-diethylurea Derivatives 新型3-(2,5-二氧基咪唑烷-1-基)-1,1-二乙基脲衍生物的合成、表征及抗氧化活性研究

Chemical science transactions Pub Date : 2019-10-10 DOI: 10.7598/cst2019.20190008

H. N. Deepakumari, M. Raghu, C. Kumar

引用次数: 0

Volumetric Behavior of Binary Mixtures of Tetrahydrofuran and C1-C4 Alkoxyethanols at Different Temperatures 四氢呋喃与C1-C4烷氧乙醇二元混合物在不同温度下的体积行为

Chemical science transactions Pub Date : 2019-10-10 DOI: 10.7598/cst2019.1588

Benjamin Amabibi Jumbo, A. Kemeakegha, C. Abasi

{"title":"Volumetric Behavior of Binary Mixtures of Tetrahydrofuran and C1-C4 Alkoxyethanols at Different Temperatures","authors":"Benjamin Amabibi Jumbo, A. Kemeakegha, C. Abasi","doi":"10.7598/cst2019.1588","DOIUrl":"https://doi.org/10.7598/cst2019.1588","url":null,"abstract":"The volumetric behavior of binary mixtures of tetrahydrofuran (THF) +2-methoxyethanol (2-MeOEtOH), + 2-ethoxyethanol (2-EtOEtOH) and 2-butoxyethanol (2-BuOEtOH) were studied at 293.15, 298.15 and 303.15 K to identify the types and strengths of intermolecular interactions taking place in the solvent systems. The densities, ρ, of the pure solvents and the binary mixtures ranging from 0.0003-0.9997 of THF were obtained at the working temperatures. Excess molar volumes, V, of the binary mixtures were calculated from the density data. The calculated excess molar volumes were fitted into the Redlich-Kister polynomial and the fitting coefficients, Ai, obtained. The values of excess molar volumes were negative in all the solvent systems and at all temperatures in the mole fraction region of0.00-0.50 THF. Beyond the mole fraction region of 0.50, the excess molar volumes were slightly positive. The negative excess molar volumes in the region of low THF concentration are attributed to intermolecular hydrogen bonding between unlike molecules of THF and the alkoxyethanols. The magnitudes of the negative excess molar volumes were also found to be dependent upon the chain length of the alkoxy group and the temperature. The results show that the excess molar volumes become more negative when the chain length of the alkoxy group increased and this was attributed to the relative proton-donating ability of the alkoxyethanols investigated.","PeriodicalId":10087,"journal":{"name":"Chemical science transactions","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89821461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Detection and Identification of Tranquilizer in Biological and Non-Biological Samples in Case of Tigress with History of Homicide 有杀人史的母老虎生物与非生物样本中镇定剂的检测与鉴定

Chemical science transactions Pub Date : 2019-10-10 DOI: 10.7598/cst2019.1593

Charansing B. Ghoti, Swati V. Sonde, Keshav S. Kapgate, Ajit R. Kokare, Shivangi S. Apte, V. J. Thakre

引用次数: 0

Electrochemical Determination of Cardiovascular Drug Cilnidipine at Glassy Carbon Electrode in Pharmaceutical Formulations 在玻碳电极上电化学测定心血管药物西尼地平的含量

Chemical science transactions Pub Date : 2019-10-10 DOI: 10.7598/cst2019.1597

R. Sharma, Mahadeva Singh Jat, K. K. Jhankal, D. K. Sharma

{"title":"Electrochemical Determination of Cardiovascular Drug Cilnidipine at Glassy Carbon Electrode in Pharmaceutical Formulations","authors":"R. Sharma, Mahadeva Singh Jat, K. K. Jhankal, D. K. Sharma","doi":"10.7598/cst2019.1597","DOIUrl":"https://doi.org/10.7598/cst2019.1597","url":null,"abstract":"Electrochemical behaviour of cilnidipine at glassy carbon electrode was investigated using cyclic, square wave cathodic adsorptive stripping (SW-CAdS) and differential pulse cathodic adsorptive stripping (DP-CAdS) voltammetry under different experimental conditions. The voltammetric peak current and potential for the reduction of cilnidipine were analysed at different pH, scan rate and concentration. The voltammograms exhibited irreversible reduction of cilnidipine in B R buffer of pH 5.5. Cilnidipine gave one well-defined reduction peak at -0.821 potential versus Ag/AgCl reference electrode in BR buffer of pH 5.5. Reduction process was irreversible and diffusion controlled. Diffusion coefficients (7.45x10 cm/s and 6.45x10 cm/s), surface coverage (4.23x10mol/cm and 98.01x10mol/cm) and heterogeneous rate constant (1.25x10s) were calculated at bare GCE respectively. Based on CV, CPC and pH studies a reduction mechanism was proposed involving 6H/6e. The proposed square wave voltammetric method shows linearity over the concentration range (4.21x10-9.71x10 M) The achieved limits of detection (LOD) and quantification (LOQ) are 5.44x10 g/mL and 1.52x10g/mL respectively.","PeriodicalId":10087,"journal":{"name":"Chemical science transactions","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88790250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Insights into the Chemistry of cis-Dioxomolybdenum(VI) Schiff Base Complexes with Macrocyclic Ligands 顺式二氧钼(VI)席夫碱配合物与大环配体的化学新认识

Chemical science transactions Pub Date : 2019-10-10 DOI: 10.7598/cst2019.1594

R. K. Gautam, C. Singh, D. Kumar, D. P. Rao

引用次数: 1

Characteristics, Properties and Analytical Methods of Cefquinome - A Review 头孢醌的特性、性质及分析方法综述

Chemical science transactions Pub Date : 2019-10-10 DOI: 10.7598/cst2019.1488

S. Shantier

引用次数: 2

Synthesis of Substituted Azetidinones Derived from Dimer of Apremilast 由阿普拉米司特二聚体衍生的取代氮杂二酮的合成

Chemical science transactions Pub Date : 2019-07-08 DOI: 10.7598/cst2019.1579

Y. Jagannadham, Dodda Vivekananda Reddy, B. Ramadevi, B. Prasanna

{"title":"Synthesis of Substituted Azetidinones Derived from Dimer of Apremilast","authors":"Y. Jagannadham, Dodda Vivekananda Reddy, B. Ramadevi, B. Prasanna","doi":"10.7598/cst2019.1579","DOIUrl":"https://doi.org/10.7598/cst2019.1579","url":null,"abstract":"Over the past decade, design of 2-azetidinones scaffold has attracted greater interest of synthesis because of more biological and pharmacological potencies. Specifically, sulfonamide rings and their derivatives represent a medicinally and pharmaceutically important class of heterocyclic motifs that are found as the core structural skeletons in a variety of several naturally occurring alkaloids. We effectively intended 4-(3-chloro-2-oxo-4-aryllazetidin-1-yl)-2-(1-(3-ethoxy-4methoxyphenyl)-2-(methylsulfonyl)-ethyl)-2,4′-biisoindoline-1.1′3,3′-tetraones (6(a-f)). 4-Amino-2′(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-2,4′-biisoindo line-1, 1′, 3, 3′-tetraone 3 was prepared by condensation of 3-aminophthalic acid 2 with 1,3-ethoxy-4-methoxyphenyl)-2methylsutfonylethylamine 1 by a single step. Condensation of compound 3 with various aromatic aldehydes gives substituted Schiff base of 2′-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)2,4′-biisoindoline-1,1′,3,3′-tetraones (5(a-f)) which upon dehydrative annulation in the presence of chloroacetylchloride in the presence of triethylamine in DCM solvent yielded 4-(3-Chloro-2-oxo-4aryllazetidin-1-yl)-2′-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)-ethyl)-2,4′-biisoindoline1.1′3,3′-tetraones 6(a-f). All the synthesized compounds were recognized by Infra Red-Vibrational spectroscopy, Proton Nuclear Magnetic Resonance, mass spectroscopy and their C, H, N analyses.","PeriodicalId":10087,"journal":{"name":"Chemical science transactions","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90448781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0