Jornal de Pediatria (Vers?o em Português)最新文献

{"title":"Prevalence of constipation in cystic fibrosis patients: a systematic review of observational studies","authors":"Marina A. Stefano ,&nbsp;Rosana E. Poderoso ,&nbsp;Jochen G. Mainz ,&nbsp;Jose D. Ribeiro ,&nbsp;Antonio F. Ribeiro ,&nbsp;Elizete Aparecida Lomazi","doi":"10.1016/j.jpedp.2020.03.002","DOIUrl":"https://doi.org/10.1016/j.jpedp.2020.03.002","url":null,"abstract":"<div><h3>Objective</h3><p>To systematically revise the literature in search of data about the prevalence of constipation in patients with cystic fibrosis according to the publications in this field, which partly refer to guidelines defined in 2010 by the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.</p></div><div><h3>Sources</h3><p>Systematic review selecting articles based on the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses, including Cystic Fibrosis patients of all ages. Sources of information were selected to identify the articles without period limitation: CADTH – Canadian Agency for Drugs and Technologies in Health, CINAHL Complete, Clinical Trials US NIH, Cochrane Library, Embase, MEDLINE <em>via</em> Ovid, Scopus, Web Of Science, PubMed, SciELO, MEDLINE and LILACS, Health Systems Evidence, PDQ Evidence, CRD Canadian Agency for Drugs and Technologies in Health, INAHTA – International Network of Agencies for Health Technology Assessment, and PEDro.</p></div><div><h3>Findings</h3><p>The prevalence of constipation was reported in eight observational studies. Only two studies assessed the frequency of constipation as a primary objective; in the others, constipation was quoted along with the prevalence of the spectrum of gastrointestinal manifestations. Altogether, the publications included 2,018 patients, the reported prevalence varied from 10% to 57%. Only two of the six articles published after 2010 followed the definition recommended by the European Society.</p></div><div><h3>Conclusions</h3><p>Constipation is a frequent but still insufficiently assessed complaint of Cystic Fibrosis patients. The use of diverse diagnostic criteria restricts comparison and epidemiological conclusions, future studies should compulsorily apply the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition definition.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 686-692"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2020.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the tetra viral vaccine introduction on varicella morbidity and mortality in the Brazilian macro regions","authors":"Marcella Z. Ribeiro ,&nbsp;Emil Kupek ,&nbsp;Paulo V.Z. Ribeiro ,&nbsp;Carlos Eduardo Andrade Pinheiro","doi":"10.1016/j.jpedp.2019.12.001","DOIUrl":"https://doi.org/10.1016/j.jpedp.2019.12.001","url":null,"abstract":"<div><h3>Objective</h3><p>To describe the impact of the introduction of the viral tetra vaccine in the National Immunization Program in 2013 for 15‐month‐old children in mortality rates and hospitalization associated with varicella in Brazil.</p></div><div><h3>Methods</h3><p>Mortality rates and hospitalizations rates associated with varicella were evaluated between 2010 and 2016 and described according to Brazilian macro regions and age. The population was stratified into age groups: &lt; 1 year, 1‐4 years, and 5‐14 years. Data were collected from the Informatics Department of the Unified Health System. A percentage difference was calculated between rates of hospitalizations and mortality in the pre (2010‐2012) and post‐vaccination periods (2014‐2016) to estimate the approximate effectiveness of the vaccine.</p></div><div><h3>Data synthesis</h3><p>At the national level, vaccination significantly reduced the mortality rates and hospitalizations rates in all age groups analyzed. Among those under 5 years of age, mortality rates and hospitalizations rates decreased 57‐49% and 40‐47%, respectively. There was a national decrease of up to 57% in the mortality rates due to the disease, with smaller decreases seen in the North and Northeast regions and the largest in the South and Southeast regions. The hospitalizations rates for varicella reached a maximum national decline of 47%. In children aged 1–4 years, with higher vaccination coverage, the highest reduction was observed in both mortality rates and hospitalizations rates, which decreased from 2.6 to 0.4/100,000/year.</p></div><div><h3>Conclusions</h3><p>The tetra vaccine proved to be effective in reducing both mortality and hospitalizations of children and adolescents up to 15 years of age in the 2014‐2016 triennium.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 702-709"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.12.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distal intestinal obstruction syndrome: a diagnostic and therapeutic challenge in cystic fibrosis","authors":"Natascha S. Sandy ,&nbsp;Lilian H.P. Massabki ,&nbsp;Aline C. Gonçalves ,&nbsp;Antonio F. Ribeiro ,&nbsp;Jose D. Ribeiro ,&nbsp;Maria de Fátima C.P. Servidoni ,&nbsp;Elizete A. Lomazi","doi":"10.1016/j.jpedp.2019.08.007","DOIUrl":"https://doi.org/10.1016/j.jpedp.2019.08.007","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the demographics, genotype, and clinical presentation of pediatric patients presenting with distal intestinal obstruction syndrome (DIOS), and factors associated with DIOS recurrence.</p></div><div><h3>Methods</h3><p>Case series of ten patients (median age 13.2 years), followed‐up in a reference center, retrospectively assessed. Data analyzed included age, gender, cystic fibrosis genotype, meconium ileus at birth, hydration status, pulmonary exacerbation, <em>Pseudomonas aeruginosa</em> colonization, pancreatic insufficiency (PI), body mass index (BMI) at the episodes, clinical manifestations of DIOS, imaging studies performed, acute management of DIOS, maintenance therapy, and recurrence on follow‐up.</p></div><div><h3>Results</h3><p>All patients had two positive sweat chloride tests, and nine of ten also had genotype study. The most common genotype identified was homozygosis for the delta F508 mutation. In seven cases, a previous history of meconium ileus was reported. All patients had pancreatic insufficiency. Diagnosis of DIOS was based on clinical and imaging findings. Of the total number of episodes, 85% were successfully managed with oral osmotic laxatives and/or rectal therapy (glycerin enema or saline irrigation). Recurrence was observed in five of ten patients.</p></div><div><h3>Conclusion</h3><p>In this first report of pediatric DIOS in South America, the presence of two risk factors for DIOS occurrence was universal: pancreatic insufficiency and severe genotype. Medical history of meconium ileus at birth was present in most patients, as well as in the subgroup with DIOS recurrence. The diagnosis relied mainly on the clinical presentation and on abdominal imaging. The practices in the management of episodes varied, likely reflecting changes in the management of this syndrome throughout time.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 732-740"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.08.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baked egg tolerance: is it possible to predict?","authors":"Lisis Karine Vilar,&nbsp;Pedro Rocha Rolins Neto,&nbsp;Mariana Amorim Abdo,&nbsp;Marina Fernandes Almeida Cheik,&nbsp;Christiane Pereira e Silva Afonso,&nbsp;Gesmar Rodrigues Silva Segundo","doi":"10.1016/j.jpedp.2019.08.003","DOIUrl":"https://doi.org/10.1016/j.jpedp.2019.08.003","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the frequency of baked egg tolerance in IgE‐mediated egg allergy patients through the oral food challenge and to assess the tolerance predictability of different skin prick tests, as well as specific serum IgE measurement to egg proteins.</p></div><div><h3>Methods</h3><p>In this cross‐sectional study, 42 patients with a diagnosis of egg allergy were submitted to different skin prick tests with egg (<em>in natura</em>, boiled, muffin, ovalbumin, and ovomucoid), and specific IgE to egg white, ovalbumin, and ovomucoid; as well as to the oral food challenge with food containing egg, extensively baked in a wheat matrix.</p></div><div><h3>Results</h3><p>Of the total, 66.6% of patients tolerated the ingestion of egg‐containing foods in the oral food challenge. A comparative analysis with positive and negative oral food challenge found no significant differences regarding age, gender, other food allergies, or even specific skin prick tests and IgE values between the groups.</p></div><div><h3>Conclusions</h3><p>The study demonstrated an elevated frequency of baked egg food‐tolerant individuals among egg allergy patients. None of the tested markers, skin prick tests, or specific IgE, were shown to be good predictors for identifying baked egg‐tolerant patients. The oral food challenge with egg baked in a matrix is central to demonstrate tolerance and the early introduction of baked foods, improving patients’ and families’ quality of life and nutrient intake.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 725-731"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of risk factors for bullying perpetration and victimization","authors":"David P. Farrington","doi":"10.1016/j.jpedp.2020.05.001","DOIUrl":"https://doi.org/10.1016/j.jpedp.2020.05.001","url":null,"abstract":"","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 667-669"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2020.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Red reflex test at the maternity hospital: results from a tertiary hospital and variables associated with inconclusive test results","authors":"Vinicius Mac Cord Lanes Baldino ,&nbsp;Gabriela Unchalo Eckert ,&nbsp;Juliana Rossatto ,&nbsp;Mário Bernardes Wagner","doi":"10.1016/j.jpedp.2019.08.009","DOIUrl":"https://doi.org/10.1016/j.jpedp.2019.08.009","url":null,"abstract":"<div><h3>Objectives</h3><p>Describe the results of the red reflex test in full‐term newborns, as well as identify factors associated with red reflex test outcome and compare hospital length of stay between patients with inconclusive and normal red reflex test results.</p></div><div><h3>Methods</h3><p>Descriptive cross‐sectional study of the results of the red reflex test performed in a tertiary hospital maternity unit between 2014 and 2018. A nested case‐control study was also performed to search for anthropometric, gestational, and neonatal variables associated with the outcome of the red reflex test.</p></div><div><h3>Results</h3><p>There were121 identified cases of inconclusive red reflex test in 11,833 newborns. Sixteen alterations were confirmed, four considered severe: two cases of congenital glaucoma, one of cataract, and one of coloboma. Mean birth weight (p = 0.04), length (p = 0.03), and head circumference (p = 0.02) were lower in patients with inconclusive red reflex test; however without a relevant effect size (d = ‐0.21, ‐0.22, and ‐0.25, respectively).The proportion of white, mixed‐race, and black patients was significantly different between the groups (p &lt; 0.001), with a higher chance of inconclusive results in mixed‐race (OR = 2.22) and black (OR = 3.37) patients when compared to whites. An inconclusive red reflex test led to an increase in hospital length of stay from 62 to 82<!--> <!-->hours (p &lt; 0.001).</p></div><div><h3>Conclusions</h3><p>The red reflex test was able to identify four severe alterations in 11,833 newborns (0.03%). In the 121 newborns in which the red reflex test was classified as inconclusive, there was a 20‐hour increase in the hospital length of stay, but a severe alteration was confirmed in only 3.3% of them. Differences in red reflex between white, mixed‐race, and black patients should be considered.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 748-754"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.08.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of gestational and perinatal factors on body composition of full‐term newborns","authors":"Sylvia Reis Gonçalves Nehab,&nbsp;Letícia D. Villela,&nbsp;Andrea D. Abranches,&nbsp;Daniele M. Rocha,&nbsp;Leila M.L. da Silva,&nbsp;Yasmin N.V. Amaral,&nbsp;Saint Clair G. Junior,&nbsp;Fernanda V.M. Soares,&nbsp;Maria Dalva Barborsa Beker Méio,&nbsp;Maria Elisabeth L. Moreira","doi":"10.1016/j.jpedp.2019.09.006","DOIUrl":"https://doi.org/10.1016/j.jpedp.2019.09.006","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the influence of gestational and perinatal factors on body composition and birth weight of full‐term newborns.</p></div><div><h3>Method</h3><p>This was a cross‐sectional study, within a prospective cohort, consisting of 124 postpartum women and their newborns. Data included the following: maternal age; ethnicity; pre‐gestational body mass index; gestational weight gain; parity; gestational morbidities (hypertension and gestational diabetes mellitus); gestational age at birth; birth weight; and newborn's gender. Anthropometric and body composition data of the newborns were collected using air‐displacement plethysmography (PeaPod® Infant Body Composition System–LMI; Concord, CA, USA). The stepwise technique was applied to a multiple linear regression model.</p></div><div><h3>Results</h3><p>The significant variables in the model that explained 84% of the variation in neonatal fat‐free mass were: birth weight; maternal age; newborn's gender and gestational age. For body fat mass: birth weight; newborn's gender; gestational arterial hypertension; gestational diabetes; and gestational weight gain. These variables explained 60% and 46% of fat mass, in grams and as a percentage, respectively. Regarding birth weight, the significant factors were gestational age, pre‐gestational BMI, and gestational weight gain. Female newborns showed higher body fat mass and male newborns had higher fat‐free mass.</p></div><div><h3>Conclusion</h3><p>Gestational and perinatal factors influence neonatal body composition. Early identification of these gestational factors, which may be modifiable, is necessary to prevent obesity and chronic noncommunicable diseases in the future.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 771-777"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.09.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short‐time effect of the kangaroo position on electromyographic activity of premature infants: a randomized clinical trial","authors":"Kaísa Trovão Diniz ,&nbsp;José Eulálio Cabral Filho ,&nbsp;Rafael Moura Miranda ,&nbsp;Geisy Maria Souza Lima ,&nbsp;Natália Priscila dos Santos Figueredo ,&nbsp;Kalline Fernanda Nunes de Araújo","doi":"10.1016/j.jpedp.2019.08.010","DOIUrl":"https://doi.org/10.1016/j.jpedp.2019.08.010","url":null,"abstract":"<div><h3>Objective</h3><p>To verify the short‐term influence of the kangaroo position (KP) on the electromyography activity of preterm newborns.</p></div><div><h3>Method</h3><p>A clinical study was conducted in a kangaroo unit sector (secondary and tertiary care) in the city of Recife, Brazil, with 44 preterm infants randomized to intervention (n = 21) and control (n = 23) groups<strong>.</strong> The KP was performed through a band that supports the newborn against the adult's thorax, in a prone and vertical position, and infants were dressed with few pieces of clothes, thus keeping skin‐to‐skin contact with the mother. Surface electromyography was used to investigate the muscle activity of the biceps brachii and hamstrings. The randomization of the groups was performed by the program R® (v. 3.3.1). The electromyography registrations were made at three different times: before the KP and after one and two hours of KP. In the control group, the registrations were performed at the times corresponding to those of the intervention group. The mean values of the electromyography activity among the times were analyzed by ANOVA for repeated measures and the Kruskal‐Wallis test. The clinical trial was recorded in ClinicalTrials.gov (NCT02849665 ‐ 07/28/2016).</p></div><div><h3>Results</h3><p>In the intervention group (n = 21), there was a variation of the electromyography activity values between the three recording moments for both the biceps brachii and hamstrings. In the control group (n = 23), there was no statistical difference between the recording moments for both.</p></div><div><h3>Conclusions</h3><p>The KP increases the short‐term electromyographic activity of the biceps brachii and hamstrings.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 741-747"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.08.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multichannel intraluminal impedance‐pH and psychometric properties in gastroesophageal reflux: systematic review","authors":"Emília Silva Gonçalves,&nbsp;Maíra Seabra de Assumpção,&nbsp;Maria Fátima Correa Pimenta Servidoni,&nbsp;Elizete Aparecida Lomazi,&nbsp;José Dirceu Ribeiro","doi":"10.1016/j.jpedp.2020.03.001","DOIUrl":"https://doi.org/10.1016/j.jpedp.2020.03.001","url":null,"abstract":"<div><h3>Objective</h3><p>Systematically assess studies that have analyzed the psychometric properties of multichannel intraluminal impedance‐pH for the diagnosis of gastroesophageal reflux. Systematically verify studies that have analyzed the psychometric properties of multichannel intraluminal impedance‐pH regarding the diagnosis of gastroesophageal reflux disease in pediatric patients.</p></div><div><h3>Methods</h3><p>Systematic review considering specific descriptors (children and adolescents, gastroesophageal reflux disease and multichannel intraluminal impedance‐pH) and their synonyms. The systematic search was carried out in the MEDLINE/Ovid, Scopus, and Embase databases, considering the period from October 2017 to December 2018. This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA), which was used for study selection. The psychometric properties described in the studies were: sensitivity, specificity, accuracy, and reproducibility.</p></div><div><h3>Results</h3><p>Sensitivity was discussed in most studies, with a result of more than 70% in four of them. Specificity was assessed only in conjunction with sensitivity, with values from 23% to 25% in two studies, and it reached 80% in a single study. Accuracy was assessed higher than 76% in one of the selected articles. The methodological quality of the studies demonstrated low risk of bias, and there was no significant concern related to applicability of the studies.</p></div><div><h3>Conclusions</h3><p>According to the selected studies, multichannel intraluminal impedance‐pH was considered a safe and effective tool, presenting higher sensitivity values than pHmetry regarding the diagnosis of gastroesophageal reflux disease.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 673-685"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2020.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep and restless legs syndrome in female adolescents with idiopathic musculoskeletal pain","authors":"Rita Aparecida Ribeiro Amorim ,&nbsp;Gustavo A. Moreira ,&nbsp;Flavia Heloisa Santos ,&nbsp;Maria Teresa Terreri ,&nbsp;Juliana Molina ,&nbsp;Lívia de Freitas Keppeke ,&nbsp;Simone Guerra Lopes da Silva ,&nbsp;Melissa Mariti Fraga ,&nbsp;Vanessa Bugni Miotto e Silva ,&nbsp;Sergio Tufik ,&nbsp;Claudio Arnaldo Len","doi":"10.1016/j.jpedp.2019.08.012","DOIUrl":"https://doi.org/10.1016/j.jpedp.2019.08.012","url":null,"abstract":"<div><h3>Objectives</h3><p>To assess the presence of restless legs syndrome, periodic leg movement, and sleep disorders in female adolescents with idiopathic musculoskeletal pain through a sleep scale and polysomnography, and to compare these data in adolescents without pain history.</p></div><div><h3>Method</h3><p>Twenty‐six adolescents diagnosed with idiopathic musculoskeletal pain followed in a pain outpatient clinic and 25 healthy controls matched by age and education were recruited. The restless legs syndrome criteria were evaluated according to the International Restless Legs Syndrome Study Group, the Sleep Disturbance Scale for Children was completed, nocturnal polysomnography was performed, and anxiety symptoms were recorded.</p></div><div><h3>Results</h3><p>The mean age of idiopathic musculoskeletal pain adolescents was 13.9 ± 1.6 years; in controls, it was 14.4 ± 1.4 years. One adolescent in the control group (4%) and nine patients with idiopathic musculoskeletal pain (34.6%) fulfilled the restless legs syndrome criteria (p = 0.011). The authors did not observe significant differences in Sleep Disturbance Scale for Children scores between the groups in all components: disorders of initiating and maintaining sleep (p = 0.290), sleep breathing disorders (p = 0.576), disorders of arousal (p = 0.162), sleep‐wake transition disorders (p = 0.258), disorder of excessive daytime somnolence (p = 0.594), and sleep hyperhidrosis (p = 0.797). The neurophysiological, respiratory, and periodic leg movement parameters were similar in both groups. Having anxiety was not associated with restless legs syndrome (p = 0.11). Three patients with idiopathic musculoskeletal pain (11.5%) presented restless legs syndrome and periodic leg movement simultaneously, which was absent in the control group.</p></div><div><h3>Conclusion</h3><p>Female adolescents with idiopathic musculoskeletal pain present criteria for RLS more frequently than healthy adolescents. However, this study did not observe relevant changes in objective and subject sleep variables.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 6","pages":"Pages 763-770"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.08.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}