Insulin最新文献_第2页

Case study responses 案例研究回应

Insulin Pub Date : 2010-01-01 DOI: 10.1016/S1557-0843(10)80010-7

Ronald Tamler MD, PhD, Derek LeRoith MD, PhD

引用次数: 0

Case study 案例研究

Insulin Pub Date : 2010-01-01 DOI: 10.1016/S1557-0843(10)80011-9

Emily J. Gallagher MB, BCh, MRCPI

引用次数: 0

Making our diabetes patients' office visits more productive 使我们的糖尿病患者的办公室访问更有成效

Insulin Pub Date : 2010-01-01 DOI: 10.1016/S1557-0843(10)80005-3

Timothy S. Reid MD

引用次数: 0

Low blood sugar 低血糖

Insulin Pub Date : 2010-01-01 DOI: 10.1016/S1557-0843(10)80012-0

引用次数: 13

Insulin Pub Date : 2010-01-01 DOI: 10.1016/S1557-0843(10)80015-6

Mona Shimshi MD, Christopher K. Johnson MD

引用次数: 0

Azúcar en la sangre baja 如果你有以下任何症状，请立即打电话给你的医生:

Insulin Pub Date : 2010-01-01 DOI: 10.1016/S1557-0843(10)80013-2

引用次数: 0

Appropriate, timely, and rational treatment of type 2 diabetes mellitus: Meeting the challenges of primary care 适当、及时、合理的治疗2型糖尿病:迎接初级保健的挑战

Insulin Pub Date : 2009-07-01 DOI: 10.1016/S1557-0843(09)80029-8

Jeff Unger MD, Christopher G. Parkin MS

{"title":"Appropriate, timely, and rational treatment of type 2 diabetes mellitus: Meeting the challenges of primary care","authors":"Jeff Unger MD, Christopher G. Parkin MS","doi":"10.1016/S1557-0843(09)80029-8","DOIUrl":"10.1016/S1557-0843(09)80029-8","url":null,"abstract":"<div>Diabetes now affects >24 million people in the United States. As the prevalence of diabetes continues to increase, long-term complications of diabetes have emerged as major health care issues. Although much focus has been placed on diabetes, it is important to note that prediabetes, the intermediate state of type 2 diabetes mellitus (DM), is not benign. The progression to type 2 DM for patients with impaired glucose tolerance (IGT) is 6% to 10% per year; for persons with both impaired fasting glucose and IGT, the cumulative incidence of diabetes in 6 years may be as high as 60%. Given the significant clinical and financial impact of both conditions, it is vital that clinicians initiate treatment of diabetes and prediabetes early and aggressively. Despite advances in diabetes treatment, many health care providers do not initiate or intensify therapy appropriately during patient visits, which contributes to poor diabetes control. Although management of blood pressure and lipid levels can be complex, glycemic control is often problematic for patients and their clinicians. Thus, clinicians must learn to use the various pharmacologic and nonpharmacologic strategies effectively to achieve glucose targets in their patients with type 2 DM. Patients with prediabetes should be managed with a combination of lifestyle intervention and appropriately timed pharmacotherapy. Pancreatic β-cell preservation should be a primary metabolic target.</div>","PeriodicalId":100678,"journal":{"name":"Insulin","volume":"4 3","pages":"Pages 144-157"},"PeriodicalIF":0.0,"publicationDate":"2009-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1557-0843(09)80029-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88317559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Metabolic surgery for type 2 diabetes mellitus 代谢手术治疗2型糖尿病

Insulin Pub Date : 2009-07-01 DOI: 10.1016/S1557-0843(09)80028-6

Jonathan Klonsky MD, Michel M. Murr MD

{"title":"Metabolic surgery for type 2 diabetes mellitus","authors":"Jonathan Klonsky MD, Michel M. Murr MD","doi":"10.1016/S1557-0843(09)80028-6","DOIUrl":"10.1016/S1557-0843(09)80028-6","url":null,"abstract":"<div>Background: Metabolic surgery for morbid obesity induces significant weight loss and resolution of many obesity-related comorbidities, the most notable of which is remission of type 2 diabetes mellitus (DM). Such changes seem to precede significant weight loss in this population shortly after undergoing diversionary procedures.Objective: This article explores the evidence for salutary metabolic benefits of bariatric surgery, with special emphasis on glycemic control and remission of type 2 DM.Methods: We conducted a query of the PubMed database for articles published in English within the past 15 years using the search terms bariatric surgery, obesity, type 2 diabetes, gastric bypass, gastric banding, incretins, enteroinsular axis, GLP-1 (glucagon-like peptide-1), and GIP (glucose-dependent insulinotropic polypeptide). We targeted review articles as well as those discussing the effects of bariatric surgery on the enteroinsular axis and the respective effects on glyce-mic control.Results: Most of the clinical reports indicated a high remission rate (≥85%) for type 2 DM, and relatively higher rates in patients who underwent diversionary procedures. Studies with small cohorts and laboratory data suggested a role for gastrointestinal hormones in the regulation of glucose homeostasis after bariatric surgery.Conclusions: Gastrointestinal surgery for severe obesity, through restrictive and/or neurohormonal effects, is an effective treatment for type 2 DM. Surgically induced weight loss was found to be sustainable, durable, and associated with remission of type 2 DM, a reduction in mortality, and improvement in quality of life.</div>","PeriodicalId":100678,"journal":{"name":"Insulin","volume":"4 3","pages":"Pages 136-143"},"PeriodicalIF":0.0,"publicationDate":"2009-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1557-0843(09)80028-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88965558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Patient handout 病人资料

Insulin Pub Date : 2009-07-01 DOI: 10.1016/S1557-0843(09)80036-5

引用次数: 0

Insulin therapy: Question this issue 胰岛素治疗:质疑这个问题

Insulin Pub Date : 2009-07-01 DOI: 10.1016/S1557-0843(09)80032-8

Dina E. Green MD

引用次数: 3