Formosan Journal of Musculoskeletal Disorders最新文献_第9页

Topical Tranexamic Acid Reduces Drainage Blood Loss in Primary Total Knee Arthroplasty: A Retrospective Study 局部氨甲环酸减少初次全膝关节置换术引流出血:一项回顾性研究

Formosan Journal of Musculoskeletal Disorders Pub Date : 2015-02-01 DOI: 10.6492/FJMD.2015.0601.002

Wei-Cheng Chen, Yung-Chang Lu, Chang-Hung Huang, Te-Yang Huang, T. Kwok, Chun‐Hsiung Huang

{"title":"Topical Tranexamic Acid Reduces Drainage Blood Loss in Primary Total Knee Arthroplasty: A Retrospective Study","authors":"Wei-Cheng Chen, Yung-Chang Lu, Chang-Hung Huang, Te-Yang Huang, T. Kwok, Chun‐Hsiung Huang","doi":"10.6492/FJMD.2015.0601.002","DOIUrl":"https://doi.org/10.6492/FJMD.2015.0601.002","url":null,"abstract":"Introduction: Total knee arthroplasty (TKA) surgery is associated with significant bleeding and commonly requires allogeneic blood transfusion. Although tranexamic acid (TXA) is reported to reduce post-operative bleeding, concerns on the safety of systemic TXA and of patients with higher risk of deep-vein thrombosis or pulmonary embolism have hindered its wider use. This retrospective study aimed to assess the safety and efficacy of topical TXA in patients undergoing primary TKA. Patients and methods: Between January 2008 and December 2011, a consecutive series of 271 patients who underwent TKAs in hospital single medical center were reviewed. The TXA group received topical tranexamic acid at the end of surgery while the control group did not. Drainage blood loss was measured and the need for blood transfusion was noted. Results: Drainage blood loss was significantly lower in the topical TXA group (304.9 ± 151.2 ml) than in the control group (520.2 ± 251.2 ml) (p ＜ 0.001). Blood transfusion rate was apparently lower in the TXA-treat group (14.3%) when compared to the group without TXA (44.4%) (p=0.013). There was no increase in deep vein thrombosis or wound complication. Conclusions: In this study, topical TXA can effectively reduce blood loss and transfusion rate, and is not associated with any increase in surgical complications.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"15 1","pages":"11-15"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87412095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone Morphogenetic Protein 2 Gene Delivery via Polyethylene Imine Grafted Chondroitin Sulfate Non-viral Gene Carrier 聚乙烯亚胺移植硫酸软骨素非病毒载体骨形态发生蛋白2基因的传递

Formosan Journal of Musculoskeletal Disorders Pub Date : 2015-02-01 DOI: 10.6492/FJMD.2015.0601.004

Yu-Shiang Peng, Sydney Peng, Tsung-Ting Tsai, C. Niu, I. Chu, J. Liao, P. Lai

{"title":"Bone Morphogenetic Protein 2 Gene Delivery via Polyethylene Imine Grafted Chondroitin Sulfate Non-viral Gene Carrier","authors":"Yu-Shiang Peng, Sydney Peng, Tsung-Ting Tsai, C. Niu, I. Chu, J. Liao, P. Lai","doi":"10.6492/FJMD.2015.0601.004","DOIUrl":"https://doi.org/10.6492/FJMD.2015.0601.004","url":null,"abstract":"Background: Bone morphogenetic protein 2 (BMP-2) has been frequently used for bone regeneration. The purpose of this study was to design a gene vector to deliver the BMP-2 plasmid into cells. Polyethylene imine (PEI) is commonly used for gene transfer, however the high cytotoxicity often leads to decreased transfection efficiency. Solutions to this problem have been widely discussed, one of which being the grafting of a highly biocompatibility polymer such as chondroitin sulfate (CS). Methods: Different molecular weights (1,800 and 25,000 g/mol) of PEI were grafted onto CS (PEI1.8K-g-CS and PEI25K-g-CS, respectively) through the ethyldimethylaminopropyl carbodiimide/ N-hydroxysuccinimide reaction. This modification resulted in a non-viral gene carrier with improved biocompatibility as well as enhanced transfection efficiency compared to PEI alone. Cytotoxicity toward human embryonic kidney cell line (293T) was assayed. Results: Cell viability in the PEI-grafted-CS group was higher than that of the PEI group, and this was particularly evident at high concentrations. The efficiency of transfection and the amount of intracellular plasmid DNA were monitored using green fluorescent protein. The expression of BMP-2 was measured by enzyme-linked immunosorbent assay. A polymer:DNA weight ratio of 4:1 in the PEI25K-g-CS/DNA polyplexes exhibited the highest transfection efficiency. Conclusions: The low toxicity and high transfection efficiency of PEI25K-g-CS make it ideal for application in gene delivery and therapy.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"3 1","pages":"23-34"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90798403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late Thoracic Outlet Syndrome Following Clavicle Fracture Nonunion: A Case Report and Literature Review 锁骨骨折不愈合后的晚期胸廓出口综合征1例报告并文献复习

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-11-01 DOI: 10.6492/FJMD.2014.0504.005

Kai-Lan Hsu, J. Roan, C. Hsu, Chii-Jeng Lin, Ming-Tung Haung

引用次数: 0

Ceramic Liner Fracture in Total Hip Arthroplasty: A Report of 3 Cases 全髋关节置换术中陶瓷衬垫骨折3例报告

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-11-01 DOI: 10.6492/FJMD.2014.0504.006

Jung-Jui Chang, C. Hung, Chun-Liang Hsu, H. Shen, R. Pan, Leou‐Chyr Lin

{"title":"Ceramic Liner Fracture in Total Hip Arthroplasty: A Report of 3 Cases","authors":"Jung-Jui Chang, C. Hung, Chun-Liang Hsu, H. Shen, R. Pan, Leou‐Chyr Lin","doi":"10.6492/FJMD.2014.0504.006","DOIUrl":"https://doi.org/10.6492/FJMD.2014.0504.006","url":null,"abstract":"The ceramic on ceramic (COC) bearing surface has been utilized in total hip arthroplasty (THA) for decades. Despite the outstanding tribology of ceramic materials, ceramic fracture has been reported. Patients treated with COC THA in our database between May 2008 and April 2013 were studied with the goal of identifying factors related to ceramic fractures. The inclusion criteria were patients with preoperative and postoperative radiographs available for evaluation. The exclusion criteria were patients who were lost to follow-up and revision surgery. A total of 197 hips were treated with COC THA (171 patients) that met the inclusion criteria. Three patients were diagnosed with postoperative ceramic fractures at 9 months, 30 months, and 42 months. Two of them were resulted from intraoperative errors, including malposition of cup and improper placement of ceramic liner. One was resulted from repeated extremes of range-of-motion (ROM) of involved hip joint that increased edge-loading during daily activity. Management of ceramic fracture needed an extensive synovectomy, through irrigation of intraarticular space for complete removal of ceramic fragments and reimplantation of liners.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"1 1","pages":"170-175"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91527826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete AV Block Caused by Cervical Spondylodiscitis: A Rare Case Report 由颈椎病引起的完全性房室传导阻滞:一例罕见病例报告

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-11-01 DOI: 10.6492/FJMD.2014.0504.003

Chung-Ting Liu, Shih‐Chia Liu, Yu-Chih Liu, R. Su, Te-Yang Huang

引用次数: 0

Ipsilateral Traumatic Acetabulum Triradiate Cartilage Fracture Associated with Transphyseal Fracture of Femoral Head in Children 同侧外伤性髋臼三辐骨软骨骨折伴儿童股骨头棘突骨折

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-08-01 DOI: 10.6492/FJMD.2014.0503.003

L. Chin, Sheng-Hui Lin, Yi-Ju Lee

{"title":"Ipsilateral Traumatic Acetabulum Triradiate Cartilage Fracture Associated with Transphyseal Fracture of Femoral Head in Children","authors":"L. Chin, Sheng-Hui Lin, Yi-Ju Lee","doi":"10.6492/FJMD.2014.0503.003","DOIUrl":"https://doi.org/10.6492/FJMD.2014.0503.003","url":null,"abstract":"Traumatic fracture-separation of the capital femoral epiphysis is an extremely rare lesion in children, the prognosis is generally quite poor if it is associated with initial severe fracture displacement and hip dislocation. Traumatic disruption of the acetabular triradiate cartilage is also an infrequent injury in children, can be complicated by premature fusion of triradiate cartilage and progressive subluxation of the hip joint. Combining traumatic ipsilateral acetabular triradiate cartilage fracture and transphyseal fracture of femoral head was even more rare in children, with very limited clinical case report. Here we report an extremely rare case of a 10 years old boy with combining traumatic Salter-Harris type I proximal femoral physeal fracture, and Salter- Harris type II acetabular triradiate cartilage fracture of the left hip joint. Patient was treated by open reduction with internal screw fixation, combined postoperatively traction, crutches protection, non-weight bearing and containment treatment. Avascular necrosis of left femoral head and premature fusion of the left acetabular traradiate cartilage developed later. The short-term (15 months follow-up) clinical result was fair, and the radiologic result was poor.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"18 1","pages":"117-121"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85969271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Progressive Neurological Deficit Secondary to Lumbar Facet Synovial Cysts: Two Case Studies and a Literature Review 腰椎关节突滑膜囊肿继发进行性神经功能缺损:两个病例研究和文献回顾

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-08-01 DOI: 10.6492/FJMD.2014.0503.006

Chin-Chean Wong, Y. Tsuang, Chang-Jung Chiang, W. Ho

{"title":"Progressive Neurological Deficit Secondary to Lumbar Facet Synovial Cysts: Two Case Studies and a Literature Review","authors":"Chin-Chean Wong, Y. Tsuang, Chang-Jung Chiang, W. Ho","doi":"10.6492/FJMD.2014.0503.006","DOIUrl":"https://doi.org/10.6492/FJMD.2014.0503.006","url":null,"abstract":"This article describes two case studies involving lumbar facet joint synovial cyst causing acute sciatica and progressive neurological deficit. The cases involve women, 57 and 69 years old, respectively. The first patient was presented with left buttock and lower leg pain, numbness and paresthesia, while the second one had progressive right lower leg pain for 3 months. Magnetic resonance imaging revealed a high intensity cystic lesion arising from the facet joint, subsequently causing spinal stenosis and exiting nerve root compression. Surgery was performed, including laminectomy and cyst excision. Microscopic observation confirmed synovial cysts. Following operation, clinical symptoms of the patients improved significantly with no neurological sequelae. Based on our experience with these two patients treated by open surgery in our hospital, this study attempted to more thoroughly elucidate the significance and treatment outcome of a surgically treated lumbar synovial cyst. Moreover, relevant literature was reviewed, with a focus on their clinical presentations, imaging findings, and postoperative surgical outcomes.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"54 1","pages":"132-137"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91137245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Cauda Equina Syndrome Following Microendoscopic Decompressive laminotomy 显微内镜下椎板减压切开术后的急性马尾综合征

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-08-01 DOI: 10.6492/FJMD.2014.0503.005

J. Pao

{"title":"Acute Cauda Equina Syndrome Following Microendoscopic Decompressive laminotomy","authors":"J. Pao","doi":"10.6492/FJMD.2014.0503.005","DOIUrl":"https://doi.org/10.6492/FJMD.2014.0503.005","url":null,"abstract":"Microendoscopic decompressive laminotomy (MEDL) is a newly developed minimally invasive surgical procedure for the treatment of lumbar spinal stenosis (LSS). It is considered as effective as traditional open laminectomy for decompressing the neural stenosis, while preserving the pre-operative stability. Serious neurological complications of MEDL are seldom reported. We report a rare case of acute cauda equina syndrome following MEDL. A 53 year-old woman received MEDL for severe LSS at level L4-5. Bilateral decompression via unilateral approach was attempted but only unilateral decompression was actually performed due to technical difficulty. No dura or nerve root injury was noted during the procedure. The post-operative course was initially uneventful but she experienced slowly progressive sensory impairment on the contralateral lower limb and sphincter dysfunction after the second post-operative day. We performed wide laminectomy on the fifth post-operative day and no neural tissue injury was identified. At 6-month follow-up, the sensory impairment as well as bladder and bowel incontinence remained unimproved. Although MEDL is considered as a safe and effective procedure, severe neurological complications can occur without gross neural tissue injury. The possible causes may be attributed to inadequate decompression combined with post-operative edema of the neural tissue. We suggest bilateral approach or conversion to open surgery for cases with severe stenosis.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"114 1","pages":"127-131"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75299043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Outcomes of Medial Patellofemoral Ligament Reconstruction Using Semitendinosus Autograft for Recurrent Patellar Dislocation 自体半腱肌重建髌股内侧韧带治疗复发性髌骨脱位的临床效果

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-08-01 DOI: 10.6492/FJMD.2014.0503.002

Sheng-Hsun Lee, Shih-Sheng Chang, I.-Jung Chen, Chun-Ying Cheng, C. Chiu, Min-Chain Tsai, K. Hsu, Y. Chan

{"title":"Clinical Outcomes of Medial Patellofemoral Ligament Reconstruction Using Semitendinosus Autograft for Recurrent Patellar Dislocation","authors":"Sheng-Hsun Lee, Shih-Sheng Chang, I.-Jung Chen, Chun-Ying Cheng, C. Chiu, Min-Chain Tsai, K. Hsu, Y. Chan","doi":"10.6492/FJMD.2014.0503.002","DOIUrl":"https://doi.org/10.6492/FJMD.2014.0503.002","url":null,"abstract":"Background: Recurrent patellar dislocation is a rare but complex issue. Medial patellar stabilizer insufficiency, particularly with the medial patellofemoral ligament (MPFL), is commonly present in these patients. There are several surgical methods to address this problem. Purpose: To evaluate the clinical outcome of MPFL reconstruction when using a semitendinosus autograft and a novel tendon fixation technique to treat recurrent patellar dislocation. Methods: Twelve consecutive patients (5 males, 7 females) who failed in conservative treatment were enrolled into this prospective study. They were treated with MPFL reconstruction using a semitendinosus autograft. The mean follow-up time was 16.7 months (range, 14-22 months). Preoperative and postoperative radiographic parameters, functional scores (e.g., Lysholm knee scoring scale and Kujala scale), and postoperative complications were evaluated. Results: Eleven of twelve patients (91.7%) had good-to-excellent outcomes. There were statistically significant improvements in the Lysholm knee scoring scale (p＜0.001) and Kujala scale (p＜0.001). Additionally, the postoperative tilt angle improved significantly (p＜0.001). Conclusions: Using a semitendinosus autograft with Bioscrew fixation and an additional pull-out suture during MPLF reconstruction is a safe and effective method for treating recurrent patellar dislocation in selective patients.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"19 1","pages":"107-116"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78625824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Treatment of Huge Intraosseous Lipoma of Distal Femur with Genu Valgum: A Case Report 膝外翻治疗股骨远端巨大骨内脂肪瘤1例

Formosan Journal of Musculoskeletal Disorders Pub Date : 2014-08-01 DOI: 10.6492/FJMD.2014.0503.004

Shih-Kai Cho, F. Lee, Matthew N H Wang, Nai-Phon Wang

{"title":"Treatment of Huge Intraosseous Lipoma of Distal Femur with Genu Valgum: A Case Report","authors":"Shih-Kai Cho, F. Lee, Matthew N H Wang, Nai-Phon Wang","doi":"10.6492/FJMD.2014.0503.004","DOIUrl":"https://doi.org/10.6492/FJMD.2014.0503.004","url":null,"abstract":"Intraosseous lipomas are rare benign primary tumors of the bone. The intraosseous lipoma may be asymptomatic, and then the lesion may be found incidentally during radiological investigation following an injury in the same region. Intraosseous lipoma is frequently confused histologically or radiologically with fibrous dysplasia, enchondroma, osteoblastoma, chondrosarcoma, bone cyst, and bone infarct. We report a 64-year-old woman suffered from exacerbation of climbing-stairs pain in her right knee due to a juxta-articular bone tumor in distal femur. The symptoms improved after excisional curettage of the tumor and then reconstructed with constrained condylar knee replacement. Histopathological examination of the tumor confirmed the diagnosis of intraosseous lipoma. Although intraosseous lipomas are considered benign lesions and are treated conservatively due to their propensity for spontaneous involution, curettage and grafting has been suggested in cases with painful tumors, pathological fractures or other secondary changes. Curettage and bone grafting is an option for treatment with a good clinical and functional result. And intraosseous lipoma should be considered in the differential diagnosis of osteoblastic lesions for the orthopedic surgeon.","PeriodicalId":100551,"journal":{"name":"Formosan Journal of Musculoskeletal Disorders","volume":"6 1","pages":"122-126"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87395793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0