I. Goulimaris M.D., I. Kanellos, E. Christoforidis, I. Mantzoros, Ch. Odisseos, D. Betsis
{"title":"Stapled haemorrhoidectomy compared with Milligan-Morgan excision for the treatment of prolapsing haemorrhoids: A prospective study","authors":"I. Goulimaris M.D., I. Kanellos, E. Christoforidis, I. Mantzoros, Ch. Odisseos, D. Betsis","doi":"10.1002/ejs.6161681110","DOIUrl":"https://doi.org/10.1002/ejs.6161681110","url":null,"abstract":"<p><i>Objective:</i> To compare stapled haemorrhoidectomy with Milligan-Morgan haemorrhoidectomy.</p><p><i>Design:</i> Prospective open study.</p><p><i>Setting:</i> Teaching hospital, Greece.</p><p><i>Patients:</i> 85 patients with prolapsing haemorrhoids were invited to choose between stapled and Milligan-Morgan haemorrhoidectomy. 48 chose the former and 37 the latter.</p><p><i>Interventions:</i> Operation. Postoperatively, the patients were given analgesics on demand, and were discharged as soon as their condition and particularly their pain had improved.</p><p><i>Main outcome measures:</i> Patients' symptoms and their opinion about the procedures, which were recorded during their follow-up which lasted for 6 months.</p><p><i>Results:</i> Stapling resulted in a significantly shorter operating time, and less postoperative pain and other symptoms, than Milligan-Morgan excision (<i>p</i> < 0.001). Postoperative complications, and mean time in hospital did not differ significantly between the two groups. During the follow-up period there was no significant difference in the incidence of recurrences between the two groups. Six months after the operation, significantly more patients in the stapled group had residual skin tags-external haemorrhoids than in the Milligan-Morgan group, and all these patients had fourth degree haemorrhoids.</p><p><i>Conclusions:</i> Stapled haemorrhoidectomy is a promising method of treatment for prolapsing third degree haemorrhoids. Its effectiveness is questionable for fourth degree ones. Initially, the results are as good as after Milligan-Morgan haemorrhoidectomy, especially for third degree haemorrhoids. However, more patients and longer follow-up periods are required for its long-term efficacy to be confirmed.</p>","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"621-625"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109162018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Neudecker, T. Junghans, S. Ziemer, W. Raue, W. Schwenk M.D.
{"title":"Influence of the sampling technique on the measurement of peritoneal fibrinolytic activity","authors":"J. Neudecker, T. Junghans, S. Ziemer, W. Raue, W. Schwenk M.D.","doi":"10.1002/ejs.6161681113","DOIUrl":"https://doi.org/10.1002/ejs.6161681113","url":null,"abstract":"<p><i>Objective:</i> To establish the influence of the peritoneal sampling technique on the measurement of fibrinolytic capacity.</p><p><i>Design:</i> Clinical study.</p><p><i>Setting:</i> University hospital, Germany.</p><p><i>Subjects:</i> 40 peritoneal biopsy specimens were taken from 10 patients who were having elective colorectal resections.</p><p><i>Interventions:</i> Peritoneal biopsy specimens were taken either with a biopsy punch (<i>n</i> = 20) or manually with forceps and scissors (<i>n</i> = 20).</p><p><i>Main outcome measures:</i> Extent of agreement in fibrinolytic activities between specimens taken with biopsy punch and manually. Major endpoint—peritoneal tissue plasminogen activator (t-PA) activity. Minor endpoints—peritoneal tissue plasminogen activator concentration, and concentration and activity of plasminogen activator inhibitior type 1 (PAI-1).</p><p><i>Results:</i> Intra-assay agreement and the extent of agreement between the groups were evaluated by the method of Bland and Altman. Correlation of repeated measurements of t-PA and PAI-1 concentrations and activities from the same sample using the same ELISA kit was high (<i>r</i> = 0.93–0.99, <i>p</i> < 0.01). t-PA activities and concentrations between the groups correlated poorly (<i>r</i> = 0.60 and 0.66, <i>p</i> < 0.01) while no correlation at all was seen for PAI-1 concentration and activity between the groups (<i>r</i> = 0.6 and 0.1, <i>p</i> = 0.2 and 0.9). The mean differences between the groups ranged from −27% to −4.8%.</p><p><i>Conclusion:</i> The sampling technique considerably affects the measurement of peritoneal fibrinolytic activity.</p>","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"635-640"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681113","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109162025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter Labas M.D., Ph.D., Bernard Ohradka, Marek Cambal, Juraj Olejnik, Juraj Fillo
{"title":"Haemorrhoidectomy in outpatient practice","authors":"Peter Labas M.D., Ph.D., Bernard Ohradka, Marek Cambal, Juraj Olejnik, Juraj Fillo","doi":"10.1002/ejs.6161681109","DOIUrl":"https://doi.org/10.1002/ejs.6161681109","url":null,"abstract":"<p><i>Objective:</i> To evaluate our results of haemorrhoidectomy done as an outpatient procedure.</p><p><i>Design:</i> Retrospective study.</p><p><i>Setting:</i> University hospital Bratislava, Slovak Republic.</p><p><i>Subject:</i> 256 patients who required haemorrhoidectomy in 1996–2001.</p><p><i>Interventions:</i> Milligan-Morgan haemorrhoidectomy under local (0.5% lignocaine with adrenaline 1:200000, 100 ml) or epidural (0.5 bupivacaine, marcain, 20 ml; or 1% lignocaine, 20 ml).</p><p><i>Main outcome measures:</i> Mortality, morbidity, need for admission to hospital, and acceptability to patients.</p><p><i>Results:</i> No patient died. All patients were observed in the recovery room for 0.5–8 hours (mean 5 hours). 23 of the 256 patients (9%) developed minor complications including bleeding (<i>n</i> = 6), pain (<i>n</i> = 15), anal discharge (<i>n</i> = 1), and retention of urine (<i>n</i> = 1). 5 patients (2%) were admitted for pain or retention of urine. During the first 3 days after operation 29 patients required increased analgesia for discomfort. 223 patients (87%) were satisfied with outpatient treatment, while the remaining would have preferred to be admitted to hospital.</p><p><i>Conclusion:</i> Day case haemorrhoidectomy is a safe and effective way of reducing costs without increasing morbidity, mortality, and is acceptable to most patients.</p>","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"619-620"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109162035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoshitaka Fujii M.D., Aki Uemura, Hiroyoshi Tanaka
{"title":"Retracted: Prophylaxis of nausea and vomiting after laparoscopic cholecystectomy with ramosetron: Randomised controlled trial","authors":"Yoshitaka Fujii M.D., Aki Uemura, Hiroyoshi Tanaka","doi":"10.1002/ejs.6161681103","DOIUrl":"https://doi.org/10.1002/ejs.6161681103","url":null,"abstract":"<p>The following article from the <i>European Journal of Surgery</i> (incorporated into the <i>British Journal of Surgery</i>), ‘Prophylaxis of nausea and vomiting after laparoscopic cholecystectomy with ramosetron: randomised controlled trial’ by Y. Fujii, A. Uemura and H. Tanaka, has been retracted by agreement between the Joint Chief Editors, Professor Derek Alderson and Mr Jonothan J. Earnshaw, and John Wiley & Sons Ltd.</p><p>The retraction statement at http://onlinelibrary.wiley.com/doi/10.1002/bjs.9110/full</p>","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"583-586"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109162042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Donata Campra M.D. U.O.A., Enzo Carlo Farina, Andrea Resegotti, Roberta Longhin, Paola Burlo, Ezio David, Gian Ruggero Fronda
{"title":"Castleman disease in differential diagnosis of a pancreatic mass","authors":"Donata Campra M.D. U.O.A., Enzo Carlo Farina, Andrea Resegotti, Roberta Longhin, Paola Burlo, Ezio David, Gian Ruggero Fronda","doi":"10.1002/ejs.6161681216","DOIUrl":"https://doi.org/10.1002/ejs.6161681216","url":null,"abstract":"","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 12","pages":"744-746"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681216","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109162615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Importance of the early increase in intestinal permeability in critically Ill patients","authors":"B. J. Ammori M.D., F.R.C.S., L. Kompan M.D.","doi":"10.1002/ejs.6161681120","DOIUrl":"10.1002/ejs.6161681120","url":null,"abstract":"","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"660-662"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681120","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72945501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Massimiliano Veroux M.D., Umberto Cillo, Carmelo Madia, Pierfrancesco Veroux, Enrico Gringeri, Pietro Fiamingo, Davide Francesco D'Amico
{"title":"Traumatic complete transsection of the left hepatic duct: Another approach to repair","authors":"Massimiliano Veroux M.D., Umberto Cillo, Carmelo Madia, Pierfrancesco Veroux, Enrico Gringeri, Pietro Fiamingo, Davide Francesco D'Amico","doi":"10.1002/ejs.6161681008","DOIUrl":"10.1002/ejs.6161681008","url":null,"abstract":"","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 10","pages":"563-565"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74366549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. K. Khanna M.D., J. K. Tapodar, H. D. Khanna, S. Khanna, Anuradha Khanna
{"title":"Behaviour of estrogen receptor, histological correlation, and clinical outcome in patients with benign breast disorders","authors":"A. K. Khanna M.D., J. K. Tapodar, H. D. Khanna, S. Khanna, Anuradha Khanna","doi":"10.1002/ejs.6161681112","DOIUrl":"https://doi.org/10.1002/ejs.6161681112","url":null,"abstract":"<p><i>Objective:</i> To estimate the value of estrogen receptor (ER) in benign breast diseases and to find out if the response of benign breast diseases to danazol depends on the ER status of the tissue.</p><p><i>Design:</i> Prospective study.</p><p><i>Setting:</i> University hospital, India.</p><p><i>Material:</i> Samples of tissue from benign breast lesions, 40 fibrocystic disease and 10 fibroadenomas.</p><p><i>Interventions:</i> Enzyme immunoassay for the presence of cytosolic ER.</p><p><i>Main outcome measures:</i> ER concentrations, and correlation with effect of treatment with danazol.</p><p><i>Results:</i> Fibrocystic disease and fibroadenomas showed 30% and 40% ER positivity, respectively. The mean (SD) ER concentration was significantly higher in premenopausal than postmenopausal patients 14.75 (3.79) fmol/mgm compared with 6.2 (1.59) fmol/mg (<i>p</i> < 0.05). All ten patients with mastalgia who had ER-positive lesions (<i>n</i> = 26) responded to danazol, compared with 6 of 16 patients who had ER-negative lesions (<i>p</i> < 0.05). Lesions with diffuse fibrosis (<i>n</i> = 14) and five with lymphocytic infiltration on histology were all ER-negative.</p><p><i>Conclusion:</i> The patients with ER positive breast disease responded better to danazol than patients with ER negative breast disease.</p>","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"631-634"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109164758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Orsenigo M.D., Marco Cristallo, Carlo Socci, Renato Castoldi, Antonio Secchi, Renzo Colombo, Laura Invernizzi, Paolo Fiorina, Richard Naspro, Valerio Di Carlo
{"title":"Urological complications after simultaneous renal and pancreatic transplantation","authors":"Elena Orsenigo M.D., Marco Cristallo, Carlo Socci, Renato Castoldi, Antonio Secchi, Renzo Colombo, Laura Invernizzi, Paolo Fiorina, Richard Naspro, Valerio Di Carlo","doi":"10.1002/ejs.6161681107","DOIUrl":"https://doi.org/10.1002/ejs.6161681107","url":null,"abstract":"<p><i>Objective:</i> To report the urological complications after simultaneous renal and pancreatic transplantation.</p><p><i>Design:</i> Retrospective study.</p><p><i>Setting:</i> Teaching hospital, Italy.</p><p><i>Subjects:</i> 143 consecutive patients having simultaneous renal and pancreatic transplantation by one of three techniques. 33 segmental pancreas with duct occlusion, 77 whole pancreas with bladder diversion, and 33 enteric diversion with systemic (<i>n</i> = 26) or portal venous drainage (<i>n</i> = 7). Urological complications were related to the pancreatic transplant, to the renal transplant, or unrelated to the transplant.</p><p><i>Main outcome measures:</i> Morbidity.</p><p><i>Results:</i> After occlusion of the duct and enteric diversion, there were no urological complications related to the pancreatic transplant. On the other hand, among the 77 patients with pancreatic drainage into the bladder, urological complications were common (56/77; 73%). Complications related to the renal transplant were recorded in 6/33 (18%), 26/77 (34%) and 12/33 (36%), respectively. Complications unrelated to the transplant occurred in 6/77 patients (8%) in the bladder drainage group. Five patients after bladder drainage required cystoenteric conversion.</p><p><i>Conclusions:</i> Enteric diversion is a safe alternative to bladder diversion and results in significantly fewer urological complications.</p>","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"609-613"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109230538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julian W. Mall M.D., Wolfgang Schwenk, Andreas W. Philipp, Joachim M. Müller, Christian Pollmann
{"title":"Thalidomide given intraperitoneally reduces the number of postoperative adhesions after large bowel resection in rabbits","authors":"Julian W. Mall M.D., Wolfgang Schwenk, Andreas W. Philipp, Joachim M. Müller, Christian Pollmann","doi":"10.1002/ejs.6161681114","DOIUrl":"https://doi.org/10.1002/ejs.6161681114","url":null,"abstract":"<p><i>Objective:</i> To investigate the effect of thalidomide given intraperitoneally on the formation of adhesions after colonic resection in rabbits.</p><p><i>Design:</i> Controlled, randomised prospective study.</p><p><i>Setting:</i> University hospital, Germany.</p><p><i>Animals:</i> 40 female New Zealand White rabbits.</p><p><i>Interventions:</i> After an end-to-end colonic anastomosis the animals were given thalidomide 200 mg/kg in 1% carboxymethylcellulose intraperitoneally or carboxymethylcellulose alone (<i>n</i> = 20 in each group).</p><p><i>Outcome measures:</i> The adhesion score according to Tyrell on day 3 (<i>n</i> = 20) and day 7 (<i>n</i> = 20) postoperatively, weight, behaviour, and white cell count (WCC).</p><p><i>Results:</i> There was no difference in behaviour or weight. On the third postoperative day WCCs and on the seventh postoperative day WCCs and adhesion scores, were lower in the thalidomide group (<i>p</i> < 0.01).</p><p><i>Conclusion:</i> The number of postoperative adhesions was reduced in the group given thalidomide intraperitoneally. Our results suggest that thalidomide may be helpful in the prevention of postoperative adhesions.</p>","PeriodicalId":100508,"journal":{"name":"European Journal of Surgery","volume":"168 11","pages":"641-645"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/ejs.6161681114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109162014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}