Coronary Health Care最新文献

{"title":"Helicobacter pylori relation to acute myocardial infarction in an Iranian sample","authors":"N. Sarraf-Zadegan ,&nbsp;M. Amiri,&nbsp;S. Maghsoudloo","doi":"10.1054/chec.2001.0145","DOIUrl":"10.1054/chec.2001.0145","url":null,"abstract":"<div><p>Known risk factors for coronary heart diseases do not explain all of clinical and epidemiological features of the disease and additional environmental factors probably contribute to clinical atherothrombotic events. This study examined the association of Helicobacter pylori (<em>H. pylori</em>) infection with acute and chronic coronary syndromes assessed by coronary angiography as well as the influence of <em>H. pylori</em> on fibrinogen level. Paired sera from 52 patients with acute myocardial infarction (AMI) according to WHO criteria, 51 patients with positive coronary angiography and 55 patients with negative coronary angiography reports were investigated for antibodies to <em>H. pylori</em> and fibrinogen levels. <em>H. pylori</em> antibodies were determined by ELISA method. Plasma fibrinogen was measured by the Clauss assay. Coronary angiograms were reviewed by two cardiologists independently (weighted κ=0.64) and significant lesion was defined as ≥50% stenosis of at least one coronary vessel. There was significant relationship between <em>H. pylori</em> infection and acute myocardial infarction (Odds ratio=13.2, 95% CI=5.1–34.3, <em>P</em>=0.00), however, no significant difference between patients with positive or negative coronary angiography (Odds ratio=2.0, 95% CI=0.76–5.35, <em>P</em>=0.24) was seen. The crude prevalence of <em>H. Pylori</em> was not related significantly to the childhood socioeconomic class (<em>P</em>&gt;0.05) while showing significant inverse relationship with current socioeconomic class (<em>P</em>&lt;0.05). Fibrinogen levels were significantly higher among <em>H. pylori</em> positive than <em>H. pylori</em> negative patients (331.7±78.2 vs 304.6±66.4 mg/dl) (<em>P</em>=0.04). While the Odds ratios for positivity of <em>H. pylori</em> antibodies in relation to smoking status, current socioeconomic classes were significant (<em>P</em>&lt;0.05), sex and childhood socioeconomic classes showed no significant association with <em>H. pylori</em> infection (<em>P</em>&gt;0.05). These results may support the hypothesis that <em>H. pylori</em> may influence acute myocardial infarction through enhancing thrombosis possibly mediated by raised fibrinogen level.</p></div>","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 202-207"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0145","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80859941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diary of Forthcoming Events","authors":"","doi":"10.1054/chec.2001.9125","DOIUrl":"https://doi.org/10.1054/chec.2001.9125","url":null,"abstract":"","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Page 220"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.9125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137403653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Helicobacter pylori and myocardial infarction: one final push for the truth?","authors":"D.S.G. Conway,&nbsp;G.Y.H. Lip","doi":"10.1054/chec.2001.0147","DOIUrl":"10.1054/chec.2001.0147","url":null,"abstract":"","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 165-166"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87108757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Summaries of research projects and reviews on a range of issues relating to coronary heart disease","authors":"B. Linden (Cardiac Nurse)","doi":"10.1054/chec.2001.0144","DOIUrl":"https://doi.org/10.1054/chec.2001.0144","url":null,"abstract":"","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 210-215"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137403654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuation and initiation of preventive care in general practice following myocardial infarction","authors":"F.L. Wright ,&nbsp;S.M. Dovey,&nbsp;T. Lancaster,&nbsp;N.R. Hicks,&nbsp;D. Mant,&nbsp;H.A.W. Neil","doi":"10.1054/chec.2001.0137","DOIUrl":"10.1054/chec.2001.0137","url":null,"abstract":"<div><p>This study assesses the extent to which general practitioners maintain hospital-initiated preventive treatment for patients one year after a myocardial infarction and initiate preventive care for patients discharged from hospital without such care. A cross-sectional study was conducted following up 565 myocardial infarction one-year survivors aged less than 80 years from two district general hospitals and 97 general practices in Oxfordshire and bordering areas. Hospital discharge records and general practice casenotes were reviewed for prescriptions of aspirin, β-blockers, ACE inhibitors, and lipid-lowering drugs. The number of patients continuing to receive hospital-initiated prescriptions one year after the acute event was: for aspirin 437/466 (94%); β-blockers 217/276 (79%); ACE-inhibitors 189/218 (87%) and lipid lowering drugs 57/66 (86%). The number of patients discharged without appropriate preventive care but receiving prescriptions initiated in general practice was: for aspirin 30/40 (75%); β-blockers 49/169 (27%); ACE-inhibitors 11/20 (55%) and lipid-lowering drugs 81/261 (31%). In conclusion, improving the implementation of evidence-based preventive care for patients with coronary heart disease is now a national priority. Most post-infarction patients were managed to a high standard, but the highest rates were attained when prescribing was initiated in hospital. Achieving optimal preventive care at hospital discharge is a crucial step in achieving appropriate long-term care in general practice.</p></div>","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 167-170"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0137","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84408017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On death, dying and not dying","authors":"HILARY HOLLIS (Senior Nurse: Clinical Trials)","doi":"10.1054/chec.2001.0146","DOIUrl":"10.1054/chec.2001.0146","url":null,"abstract":"","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 208-209"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84479323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstracts from the BACR annual conference 2001","authors":"","doi":"10.1054/chec.2001.0141","DOIUrl":"https://doi.org/10.1054/chec.2001.0141","url":null,"abstract":"","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 216-219"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0141","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137403655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac rehabilitation after coronary artery bypass graft surgery: its effect on ischaemia, functional capacity, and a multivariate index of prognosis","authors":"R. Sharma,&nbsp;A.A. McLeod","doi":"10.1054/chec.2001.0142","DOIUrl":"10.1054/chec.2001.0142","url":null,"abstract":"<div><p><em>Objective</em>: To assess the effect of cardiac rehabilitation on indices of ischaemia, functional capacity, and exercise test derived indices of prognosis in patients who undergo coronary artery bypass grafting (CABG).<em>Patients and Methods</em> : Prospective study of 150 consecutive cardiac rehabilitation patients who underwent coronary artery bypass grafting (CABG). Patients entered a hospital-based multidimensional cardiac rehabilitation programme with at least 2 months of regular supervised aerobic exercise as a main component. All patients underwent Bruce protocol exercise stress testing as a diagnostic procedure prior to surgery (ETT₁) and after surgery but prior to cardiac rehabilitation (ETT₂). A further exercise test was performed after 2 months of cardiac rehabilitation (ETT₃). Standard measurements during exercise ECG were obtained, including a Duke multivariate risk score. No restrictions were made on medical therapy. A total of 33 patients did not undergo a presurgery test, either because of unstable angina pectoris, or because of aortic stenosis. 2 patients did not complete the post rehabilitation exercise test. The data from 115 patients are presented. <em>Results</em>: Improvements in effort tolerance were seen at ETT₂ and ETT₃. (ETT₁ 3.8±0.4 min; ETT₂ 5.3±0.5 min; ETT₃ 6.4±0.5 min; all 2p&lt;0.0001). Substantial improvements were seen after surgery in indices of ischaemia (ST segment shift and chest pain) and these were not further affected by cardiac rehabilitation (mean ST depression pre surgery 1.2±0.2 mm; ST depression post surgery and rehabilitation both 0.2±0.1 mm; 2p&lt;0.0001 for change from ETT₁ only). Cardiac rehabilitation further enhanced effort tolerance, and increased maximal attainable systolic blood pressure (SBP). Maximal heart rate was unaffected (Maximal SBP: ETT₁ 161±5 mm Hg, ETT₂ 174±5 mm Hg, ETT₃ 182±5 mm Hg; 2p&lt;0.0001 for ETT₂ vs ETT₁; 2p=0.003 for ETT₃ vs ETT₂). The Duke multivariate score improved after surgery, but a further improvement was seen after cardiac rehabilitation (Duke Score ETT₁ −5.4±1.3; ETT₂ +3.8±0.7; ETT₃ +4.7±0.8; 2p ETT₂ vs ETT₁ &lt;0.0001; 2p ETT₃ vs ETT₂ &gt;0.002).<em>Conclusion</em> : Dramatic benefits occur after cardiac surgery for symptoms of ischaemic heart disease. Cardiac rehabilitation does not have a further impact on either symptoms (lack of chest pain) or indices of ischaemia (ST segment depression). Cardiac rehabilitation does however further improve effort tolerance, increase maximal double product, and improve Duke prognostic score.</p></div>","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 189-193"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75915709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving outcomes in chronic heart failure","authors":"EMMA GARDNER (Lecturer Practitioner for Cardiac Nursing)","doi":"10.1054/chec.2001.0140","DOIUrl":"10.1054/chec.2001.0140","url":null,"abstract":"","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Page 208"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0140","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80344298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition and coronary heart disease","authors":"C.R. Hankey ,&nbsp;W.S. Leslie","doi":"10.1054/chec.2001.0143","DOIUrl":"10.1054/chec.2001.0143","url":null,"abstract":"<div><p>There is increasing evidence for the protective effect of a diet low in total and saturated fat and high in fresh fruit and vegetables in the primary and secondary prevention of coronary heart disease (CHD). This review describes recent evidence and international nutritional/dietary guidelines that outline both the effects of dietary change on coronary risk and the implications for current advice offered in clinical practice. Given the considerable body of evidence, it is concluded that comprehensive dietary management should be central to the routine primary and secondary prevention of CHD.</p></div>","PeriodicalId":100334,"journal":{"name":"Coronary Health Care","volume":"5 4","pages":"Pages 194-201"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1054/chec.2001.0143","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88602995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}