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Response to Drs. Gallagher, King, and Large 对博士的回应。Gallagher, King, and Large
APS Journal Pub Date : 1994-12-01 DOI: 10.1016/S1058-9139(05)80278-5
David A. Fishbain
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引用次数: 2
Hyperalgesia following noxious thermal, mechanical, or chemical stimulation involves overlapping spinal mechanisms and interactive participation of excitatory amino acids and neuropeptides 有害的热、机械或化学刺激后的痛觉过敏涉及重叠的脊髓机制和兴奋性氨基酸和神经肽的相互作用
APS Journal Pub Date : 1994-12-01 DOI: 10.1016/S1058-9139(05)80272-4
J.L. Henry, V. Radhakrishnan
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引用次数: 4
Advantages of illness 疾病的好处
APS Journal Pub Date : 1994-12-01 DOI: 10.1016/S1058-9139(05)80277-3
Robert G. Large
{"title":"Advantages of illness","authors":"Robert G. Large","doi":"10.1016/S1058-9139(05)80277-3","DOIUrl":"10.1016/S1058-9139(05)80277-3","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"3 4","pages":"Pages 282-284"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80277-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89947276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Thermal and mechanical hyperalgesia 热和机械痛觉过敏
APS Journal Pub Date : 1994-12-01 DOI: 10.1016/S1058-9139(05)80269-4
S.T. Meller
{"title":"Thermal and mechanical hyperalgesia","authors":"S.T. Meller","doi":"10.1016/S1058-9139(05)80269-4","DOIUrl":"10.1016/S1058-9139(05)80269-4","url":null,"abstract":"<div><p>The mechanisms underlying hyperalgesia have been intensively studied over the last decade using a variety of molecular, electrophysiological, and behavioral approaches. These experiments have led to the generalized scheme that persistent nociceptor input, as a result of tissue or nerve injury, removes a magnesium block on spinal NMDA receptors, allowing for calcium influx, translocation of protein kinase C, and activation of nitric oxide synthase and soluble guanylate cyclase as important central components of hyperalgesia. However, the hypothesis proposed here suggests a need for a critical reevaluation of the generalized applicability of these events to our understanding of the mechanisms of hyperalgesia. It is proposed that thermal and mechanical hyperalgesia rely on activation of two different intracellular cascades in the spinal cord. Thermal hyperalgesia relies principally on activation of spinal NMDA receptors, translocation of protein kinase C, and production of nitric oxide and cGMP. In contrast, mechanical hyperalgesia relies principally on coactivation of spinal AMPA and metabotropic glutamate receptors, activation of phospholipase A<sub>2</sub> (PLA<sub>2</sub>), and production of cyclooxygenase products.</p></div>","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"3 4","pages":"Pages 215-231"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80269-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86173652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
疼痛在婴儿,儿童和青少年,尼尔L.谢克特,查尔斯B. Berde, Myron Yaster(编辑)。威廉姆斯和威尔金斯,纽约(1993)
APS Journal Pub Date : 1994-09-01 DOI: 10.1016/S1058-9139(05)80325-0
John D. Loeser MD
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引用次数: 0
In defense of the independent medical examiner 为独立法医辩护
APS Journal Pub Date : 1994-09-01 DOI: 10.1016/S1058-9139(05)80318-3
Scott Haldeman
{"title":"In defense of the independent medical examiner","authors":"Scott Haldeman","doi":"10.1016/S1058-9139(05)80318-3","DOIUrl":"10.1016/S1058-9139(05)80318-3","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"3 3","pages":"Pages 191-192"},"PeriodicalIF":0.0,"publicationDate":"1994-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80318-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84997605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The role of the spinothalamic tract in the plastic changes in somatosensory thalamus and cortex caused by inflammation 脊髓丘脑束在炎症引起的体感丘脑和皮质可塑性变化中的作用
APS Journal Pub Date : 1994-09-01 DOI: 10.1016/S1058-9139(05)80316-X
W.D. Willis Jr.
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引用次数: 0
Notes from membership 会员须知
APS Journal Pub Date : 1994-09-01 DOI: 10.1016/S1058-9139(05)80322-5
Stanley L. Chapman
{"title":"Notes from membership","authors":"Stanley L. Chapman","doi":"10.1016/S1058-9139(05)80322-5","DOIUrl":"https://doi.org/10.1016/S1058-9139(05)80322-5","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"3 3","pages":"Page 205"},"PeriodicalIF":0.0,"publicationDate":"1994-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80322-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138428375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From rat to man 从老鼠到人类。
APS Journal Pub Date : 1994-09-01 DOI: 10.1016/S1058-9139(05)80315-8
M. Catherine Bushnell
{"title":"From rat to man","authors":"M. Catherine Bushnell","doi":"10.1016/S1058-9139(05)80315-8","DOIUrl":"10.1016/S1058-9139(05)80315-8","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"3 3","pages":"Pages 180-182"},"PeriodicalIF":0.0,"publicationDate":"1994-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80315-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73035781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diskography is still investigational 磁盘学仍在研究中
APS Journal Pub Date : 1994-09-01 DOI: 10.1016/S1058-9139(05)80312-2
Peter R. Wilson
{"title":"Diskography is still investigational","authors":"Peter R. Wilson","doi":"10.1016/S1058-9139(05)80312-2","DOIUrl":"10.1016/S1058-9139(05)80312-2","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"3 3","pages":"Pages 163-165"},"PeriodicalIF":0.0,"publicationDate":"1994-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80312-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76666718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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