{"title":"In house customized 3D printed and designed device for marsupialization of a mandibular odontogenic cyst. Technical note","authors":"Í. Aragón Niño, E.M. Gómez García, A. Gutiérrez Venturini, M.M. Martín Pérez, J.L. Cebrián Carretero","doi":"10.1016/j.adoms.2023.100430","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100430","url":null,"abstract":"","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"11 ","pages":"Article 100430"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mamadou Diatta , Macoura Gadji , Marie Jeo Diémé , Souleymane Sarr , Mamadou Keita , Mouhammad Kane , Abdou Ba , Bintou Catherine Gassama , Babacar Tamba , Soukeye Dia Tine
{"title":"Study of the cell proliferation index (Ki67) in inflammatory odontogenic cysts","authors":"Mamadou Diatta , Macoura Gadji , Marie Jeo Diémé , Souleymane Sarr , Mamadou Keita , Mouhammad Kane , Abdou Ba , Bintou Catherine Gassama , Babacar Tamba , Soukeye Dia Tine","doi":"10.1016/j.adoms.2023.100431","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100431","url":null,"abstract":"<div><h3>Introduction</h3><p>Inflammatory odontogenic cysts are lesions that develop from the cellular remains of odontogenesis. They are lesions that may recur after incomplete surgical enucleation with a variable clinical appearance depending on the clinical form. These clinical variations could be explained by the biological behaviour of the lesion cells which can be explored by the study of the cell proliferation index (Ki67). This justifies the initiation of this work whose objective was to study the level of expression of Ki67 and to measure the index of proliferation in odontogenic inflammatory cysts.</p></div><div><h3>Material and method</h3><p>This was a cross-sectional study with an analytical aim on surgical parts of odontogenic inflammatory cysts over a period of 31 months in the odontostomatology department of the Hôpital Général Idrissa Pouye. The Ki67 immunohistochemistry study was performed on 3μ thick histological sections of paraffin-fixed tissue. The inclusion criteria were any surgical specimen of odontogenic inflammatory cyst that we could collect. The variables studied were sociodemographic, clinical and histopathological.</p></div><div><h3>Results</h3><p>Radiculo-dental cysts represented 80.5% of the surgical specimens collected and residual cysts 12.2%. The percentage of Ki67-labelled cells was greater than 15% in 80.5% of the odontogenic inflammatory cysts and less than 7% in 19.5% of the cases. In addition, intense labelling was noted in radiculo-dental cysts and weak labelling in the other clinical forms of inflammatory odontogenic cysts obtained. An association was noted between the percentage of Ki67 labelled cells and histological types (p-value <0.001); but also between the intensity of Ki67 labelling and histological types (p-value <0.001).</p></div><div><h3>Conclusion</h3><p>The cell proliferation index (Ki67) could be used as a prognostic biomarker in odontogenic inflammatory cysts.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"11 ","pages":"Article 100431"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohd Aswad Khan, Tabishur Rahman, Sajjad Abdur Rahman, Ghulam Sarwar Hashmi, Md Kalim Ansari, Mohammad Danish, Mohammad Arman, Rizwan Ahmad, Wasim Ahmad
{"title":"Is post-COVID osteonecrosis of jaw (PCONJ) Masquerading as osteomyelitis ? A largest unicentric report of 13 cases","authors":"Mohd Aswad Khan, Tabishur Rahman, Sajjad Abdur Rahman, Ghulam Sarwar Hashmi, Md Kalim Ansari, Mohammad Danish, Mohammad Arman, Rizwan Ahmad, Wasim Ahmad","doi":"10.1016/j.adoms.2023.100435","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100435","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to ascertain the correlation between COVID-19 infection and jaw osteonecrosis, along with the identification of risk factors that could be associated with the development of the condition. Another aim of our study is to establish whether maxillofacial osteonecrosis is an early or late complication seen in COVID-19 patients.</p></div><div><h3>Material and method</h3><p>This was a retrospective study conducted over a period of two years. Case records of patients with a history of severe COVID and steroid treatment who later developed jaw osteonecrosis were evaluated.</p></div><div><h3>Result</h3><p>13 patients with an age range from 8 years to 70 years were identified. Osteonecrosis was seen as late as 21 months after COVID-19. The majority of the cases involved maxilla, one case was of bi-jaw involvement, and one case presented with isolated mandibular involvement. 6 patients were diabetic and 11 patients gave a history of provocative dental treatment like extraction.</p></div><div><h3>Conclusion</h3><p>A triad of post-COVID coagulopathy, steroid administration, and a provocative dental treatment may contribute to jaw osteonecrosis which may be seen in patients without pre-existing systemic illness and may present as late as 21 months after COVID-19.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"11 ","pages":"Article 100435"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacques Gérard Edouma Bohimbo, Karl Guy Grégoire Kwedi, Stive Tamoh Fokam, Françis Daniel Nkolo Tolo, Marius Félix Mboya, Charles Bengondo Messanga
{"title":"Severity scale of cervicofacial cellulitis with a clinical experience","authors":"Jacques Gérard Edouma Bohimbo, Karl Guy Grégoire Kwedi, Stive Tamoh Fokam, Françis Daniel Nkolo Tolo, Marius Félix Mboya, Charles Bengondo Messanga","doi":"10.1016/j.adoms.2023.100433","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100433","url":null,"abstract":"<div><h3>Introduction</h3><p>Severe cervicofacial cellulitis are emergencies, mostly of odontogenic origin, and frequently observed in developing countries. Their management is still a challenge despite the improvement of the antibiotic therapy these last decades. We highlight our experience in the management of this life-threatening condition.</p></div><div><h3>Material and methods</h3><p>This was a descriptive and prospective study of all patients presenting with severe cervicofacial cellulitis between December 2020 and February 2021 in the odontostomatology department of the Garoua Regional Hospital (Cameroon). The data concerning demography (age, sex), clinical manifestations, treatment, and prognosis were analysed using SPSS version 20.0.</p></div><div><h3>Results</h3><p>45 cases of severe cervicofacial cellulitis were diagnosed, representing 13.76% of the total consultations. The female represented 55.55%. The mean age was 32.6 years. The main aetiology was odontogenic (93.33%). Clinical manifestations included swelling (100%), pain (100%), trismus (88.89%), dysphagia (53.33%), asthenia (35.56%), sepsis (4.44%). The main location involved was submandibular (75.56%). The overall severity score revealed the extremely high (24.44%), high (33.33%), and moderate (42.22%) grades. The antibiotic therapy was systematically administered. Short-course corticosteroids (46.67%), surgical debridement (88.89%), and etiological treatment (68.89%) were associated. Complications occurred in 13.33% of cases. The evolution was favourable in 95.56% of cases.</p></div><div><h3>Conclusion</h3><p>The severity of cervicofacial cellulitis can be assess with a proper recognition and evaluation of the clinical signs. This will allow the practician to better manage these conditions and to improves their prognosis.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"11 ","pages":"Article 100433"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plain film mandibular fracture detection using machine learning – Model development","authors":"Michael Rutledge , Ming Yap , Kevin Chai","doi":"10.1016/j.adoms.2023.100436","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100436","url":null,"abstract":"<div><p>The mandible is the second most fractured bone of the facial skeleton. The most common imaging modality for diagnosis are the Orthopantomogram (OPG) and posterior-anterior mandible (PAM) x-rays. This study was designed to develop a machine learning (ML) model for use to detect mandibular fractures on both OPG and PAM. 2000 consecutive incidences of orders for mandibular imaging were retrospectively collected, with 409 incidences of orders performed for the indication of trauma, and 117 incidences with fractures. These were used to train and validate the developed model. The best ML model achieved a precision of 81.9, recall of 71.9, mean Average Precision (mAP) @ 0.5 of 72.6 and F1-score of 76.5. Current research within the ML field on mandibular fractures is not standardised which makes it difficult to compare results across different datasets. ML in this research area requires standardisation and models require further development with heterogeneous and clinically relevant datasets to prove useful within the clinical environment.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"11 ","pages":"Article 100436"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49757443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel case report of primary osteosarcoma of the maxilla in an adult: An important differential diagnosis","authors":"Meena Venkatasami, Katherine Harrison","doi":"10.1016/j.adoms.2023.100423","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100423","url":null,"abstract":"<div><p>Craniofacial osteosarcoma accounts for 10% of osteosarcoma malignancies, typically affecting the 4-5th decade of life, with the maxilla being the second-most common site.</p><p>We report a 58-year-old male, non-smoker, with a lump of his upper jaw which occasionally bled during mastication. Clinical examination revealed an exophytic mass in the upper left tuberosity of the maxilla and no lymphadenopathy, where initial differential diagnosis was squamous cell carcinoma.</p><p>Radiological investigations revealed a metabolically active left maxillary lesion with maxillary sinus destruction, representing primary malignancy. Histological analyses initially suggested a fibro-osseous lesion; further immunohistochemistry showed cytokeratin AE1/AE3/CK(MNF.116) positivity with 60% ki67 proliferation index; diagnostic of grade 2–3 osteosarcoma. Management included neoadjuvant chemotherapy prior to total maxillectomy and dental prosthetic rehabilitation.</p><p>We report a novel case of primary osteosarcoma of the maxilla in an adult. Osteosarcoma is challenging to diagnose and an important differential to consider where the mainstay of treatment is early invention.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"11 ","pages":"Article 100423"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synchronous Castleman disease with renal clear cell carcinoma: A case report","authors":"Jingying Mu , Bin Jin , Jiang Zhiyan","doi":"10.1016/j.adoms.2023.100427","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100427","url":null,"abstract":"<div><p>This paper reports a case of Castleman disease. Rare parotid hyaline vascular Castleman disease with multiple hepatic cysts and kidney cancer. The patient underwent surgery and no recurrence was found during the 34-month follow-up period.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"10 ","pages":"Article 100427"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sette's elevator: A new device in oral surgery","authors":"Augusto César Sette-Dias","doi":"10.1016/j.adoms.2023.100421","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100421","url":null,"abstract":"","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"10 ","pages":"Article 100421"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49761008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Nagendra , N. Ravisankar , K. Deepthi , K. Kiran , A. Ishfaq
{"title":"Intraosseous mucoepidermoid carcinoma of mandible - A rare menace in mandible","authors":"P. Nagendra , N. Ravisankar , K. Deepthi , K. Kiran , A. Ishfaq","doi":"10.1016/j.adoms.2023.100406","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100406","url":null,"abstract":"<div><p>Salivary gland tumors makes up 3–4% of all head and neck cancers, mucoepidermoid carcinoma is a malignant locally recurrent variant of salivary gland carcinoma. .In this short communication we are presenting a rare entity of mandible “intramedullary mucoepidermoid carcinoma” treated with wide local excision (composite resection) with modified radical neck dissection followed by reconstruction with free fibula osteocutaneous flap.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"10 ","pages":"Article 100406"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zilefac Brian Ngokwe , Ntep Ntep David Bienvenue , Bola Antoine Siafa , Nokam Kamdem Stephane , Zacharie Sando
{"title":"Secondary maxillary ameloblastic carcinoma: A case report","authors":"Zilefac Brian Ngokwe , Ntep Ntep David Bienvenue , Bola Antoine Siafa , Nokam Kamdem Stephane , Zacharie Sando","doi":"10.1016/j.adoms.2023.100413","DOIUrl":"https://doi.org/10.1016/j.adoms.2023.100413","url":null,"abstract":"<div><p>Ameloblastic carcinoma is a rare malignant odontogenic neoplasm that typically develops in the mandible rather than the maxilla.</p><p>Ameloblastic carcinoma is divided into two categories: primary and secondary.</p><p>We present a case report observed at the Yaoundé University Teaching Hospital of a secondary maxillary ameloblastic carcinoma following multiple recurrences of a desmoplastic ameloblastoma in a 64-year-old female.</p><p>The diagnosis of ameloblastic carcinoma relies heavily on histology.</p></div>","PeriodicalId":100051,"journal":{"name":"Advances in Oral and Maxillofacial Surgery","volume":"10 ","pages":"Article 100413"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}