One health & implementation research最新文献

{"title":"A one-health approach to using sheep in research, with a focus on neuroscience studies","authors":"Tryfon Chatzimanou, Anastasia Tsingotjidou","doi":"10.20517/ohir.2023.13","DOIUrl":"https://doi.org/10.20517/ohir.2023.13","url":null,"abstract":"Sheep have been an important animal for both academic and basic sciences education, with a positive impact on the public health sector and, subsequently, One Health. This review presents the impact of sheep on research with a specific focus on neuroscience studies. Disorders, as well as neuroendocrine and environmental factors affecting the brain, the spinal cord, and the peripheral nervous system, are selected, and relevant research and sheep models mimicking human diseases are described. The review discusses various sheep models, encompassing prion, Parkinson’s, Alzheimer’s, Huntington’s disease, and neuronal ceroid lipofuscinoses (Batten Disease), along with ischemic stroke. Sheep play a pivotal role in elucidating the pathogenesis and/or treatment for the aforementioned diseases. Furthermore, this research is underpinned by solid neuroanatomy knowledge. Consequently, we outline the main reasons why sheep are such robust research models. In conclusion, we demonstrate the important role that sheep models fulfill in advancing the mission of the One Health Initiative.","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"143 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136102713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reemergence of arctic-like rabies virus in a rabies-free area in the Amur river basin","authors":"Aleksandr D. Botvinkin, Elena M. Poleshchuk, Sergey A. Chupin, Ivan D. Zarva, Ivan V. Meltsov, Vasily A. Yanovich, Nikolay G. Zinyakov, Gennady N. Sidorov, Evgeny Andaev, Artem E. Metlin","doi":"10.20517/ohir.2023.19","DOIUrl":"https://doi.org/10.20517/ohir.2023.19","url":null,"abstract":"Background: A descriptive epidemiological study of the rabies outbreak in the Amur Region of Russia (ARR), which remained rabies-free from 1972 to 2017, was carried out. During 2018-2022, 49 animal rabies cases and one human rabies death were documented in the ARR. This study aimed to detect possible ways of incursion and features of the spatial spread of rabies virus (RABV) in ARR, which was considered rabies-free for 45 years. Methods: After the beginning of the outbreak, 1,450 animal brain samples were tested using a direct fluorescent antibody test. Genetic analysis of RABV isolates was carried out (n = 9). GIS was used to analyze the spatial spread of rabies in ARR and adjacent territories. Results: Rabies has been confirmed in red foxes (Vulpes vulpes ) - 38.8%, raccoon dogs (Nyctereutes procyonoides ) - 10.2%, wolves (Canis lupus ) - 14.3%, dogs - 18.4% and farm animals - 18.3% (n = 49). The first cases were detected south of the ARR, 30 km from the state border between Russia and China. In 2018-2022, the RABV spread within the forest-steppe landscapes of the Zeya-Bureya Plain northwesterly; the maximum distance from the first recorded event was 192.4 km (Me = 77.6). According to a phylogenetic analysis, the isolates from ARR belonged to the Acrtic-like-2 RABV lineage and showed the maximum similarity to the isolates recovered in the province of Heilongjiang (China, 2011, 2018) and the Jewish Autonomous Region (Russia, 1980). Conclusion: Rabies was most likely introduced by wild carnivores from the adjacent territories of Russia or China, located downstream of the Amur River.","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"53 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136103975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Integrated Bite Case Management to estimate the burden of rabies and evaluate surveillance in Oriental Mindoro, Philippines.","authors":"Catherine Swedberg, Mary Elizabeth G Miranda, Criselda Bautista, David Anderson, Marife Basa-Tulio, Nai Rui Chng, Van Denn D Cruz, Mikolaj Kundegorski, Jobin Maestro, Daria Manalo, Klaudyna Maniszewska, Duane R Manzanilla, Stella Mazeri, Richard J Mellanby, Sheryl Pablo-Abarquez, Beatriz Quiambao, Shynee Vee M Telmo, Caroline Trotter, Mirava Yuson, Katie Hampson","doi":"10.20517/ohir.2023.02","DOIUrl":"10.20517/ohir.2023.02","url":null,"abstract":"<p><strong>Background: </strong>Despite national elimination efforts, dog-mediated rabies remains endemic in the Philippines. Free provision of post-exposure prophylaxis (PEP) through the widespread establishment of Animal Bite Treatment Centers (ABTCs) has improved accessibility; however, the resulting upsurge in PEP demand is not sustainable, and human rabies deaths continue. Dog vaccination coverage also remains inadequate, and it is unclear whether surveillance is effective.</p><p><strong>Methods: </strong>Here, we used Integrated Bite Case Management (IBCM) to collect enhanced rabies surveillance data in Oriental Mindoro Province over a 3-year period (2020-2022). Adapting a probabilistic decision tree model, we estimated the burden of rabies, evaluated surveillance performance, and analyzed the costs and benefits of current rabies prevention and control practices in the province.</p><p><strong>Results: </strong>The incidence of bite patients receiving PEP was high in Oriental Mindoro Province (1,246/100,000 persons/year), though < 3% of presenting patients were deemed high-risk for rabies exposure (24/100,000 persons/year). Using a decision tree model, we estimated that around 73.8% of probable rabies-exposed patients sought PEP (95% Prediction Interval, PrI: 59.4%-81.1%) and that routine surveillance confirmed < 2% of circulating animal rabies cases, whereas IBCM resulted in a nearly fourfold increase in case detection. Furthermore, we estimated that an average of 560 (95% PrI 217-1,090) dogs may develop rabies annually in the province, equating to 3-5 cases per 1,000 dogs per year. On average, 20 to 43 human deaths were averted by PEP each year in Oriental Mindoro at an annual cost of $582,110 USD (i.e., $51.44 USD per person) or $20,190 USD (95% PrI $11,565-79,400) per death averted.</p><p><strong>Conclusion: </strong>While current practices for PEP provisioning in the Philippines have improved access, a large proportion of people exposed to rabies (> 26%, 95% PrI 18.8%-40.1%) are still not seeking healthcare. Integrating an intersectoral surveillance system, such as IBCM, into national policy could greatly improve case detection if well implemented, with further benefits extending to guidance for PEP administration, potentially reducing unnecessary expenditure on PEP, and situational awareness to inform control of rabies through mass dog vaccination.</p>","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"3 ","pages":"77-96"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence of SARS-CoV-2 in southwest Goiás, Brazil, 2020: a population-based cross-sectional serological study","authors":"L. F. Costa, Roberto Barcelos Souza, Antônio Marcos Machado de Oliveira, J. Limongi","doi":"10.20517/OHIR.2021.05","DOIUrl":"https://doi.org/10.20517/OHIR.2021.05","url":null,"abstract":"Aim: The COVID-19 pandemic has been causing significant socioeconomic and health implications worldwide. We aimed to perform a population-based serological survey of SARS-CoV-2 in Quirinópolis, Goiás and to relate the infection to sociodemographic and epidemiological aspects. Methods: Systematic sampling and active search in the community was conducted using a rapid detection kit for specific IgG and IgM. Three collection phases occurred between September and October 2020. Results: In total, 557 volunteers participated in the study. The general seroprevalence rate was 8.1%, with one-off prevalence of 10.4%, 6.7% and 6.8% in each of the three phases. There was a predominance of results for IgG antibodies (88.9%). The bivariate analysis revealed that age < 19 years (OR = 5.0; 95%CI: 2.10-11.90; P = 0.0003), search for medical care (OR = 2.21; 95%CI: 1.10-4.31; P = 0.03), families of 3-4 residents (OR = 2.34; 95%CI: 1.085.05; P = 0.03) and the presence of symptoms (OR = 3.59; 95%CI: 1.92-6.78; P < 0.001) were associated with antibody detection. The symptoms related to the detection of antibodies were mainly fever (OR = 10.49; 95%CI: Page 32 Costa et al. One Health Implement Res 2021;1:31-42 https://dx.doi.org/10.20517/ohir.2021.05 4.52-23.93; P < 0.001) and abnormalities in taste (OR = 13.57; 95%CI: 6.15-29.84; P < 0.001) and smell (OR = 13.30; 95%CI: 5.36-32.99; P < 0.001). Conclusion: The high seroprevalence and predominance of IgG antibodies indicated intense circulation of the virus. These data suggest late application of protective measures, as well as population behaviour that favours viral dissemination. In this aspect, young people < 19 years of age were important, possibly due to greater exposure. The majority detection of mild symptoms was a reflection of the active search in the community.","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87833520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of human rabies surveillance and preventive measures in the State of Ceará, Northeast Brazil","authors":"N. Duarte, C. Alencar, R. Neto, Jarier de Oliveira Moreno, I. M. Melo, B. H. Duarte, J. Heukelbach","doi":"10.20517/ohir.2021.02","DOIUrl":"https://doi.org/10.20517/ohir.2021.02","url":null,"abstract":"Aim: To analyze the One Health approach regarding rabies surveillance, control, and prevention in Brazil’s Cear á State, exemplified by a detailed description of rabies cases that occurred over 18 years. Methods: We described in depth the history, case development, surveillance, and prevention measures of all cases of human rabies, 2004-2021. We analyzed patient charts and reviewed technical reports of the State Health Secretariat, in addition to analysis of personal notes from field missions. Results: All six cases occurred in rural areas. The affected people came from resource-poor communities. The state rapid response team performed comprehensive actions and seminars in collaboration with the Municipal Health Secretariats and other stakeholder groups. Patients and their relatives were not aware about the risk of wildlife-mediated rabies. A high number of wild animals (marmosets) kept as pets were collected in the communities. Only one patient presented at a primary health care center before the onset of symptoms but did not receive any post-exposure prophylaxis due to logistic problems. Even after onset of symptoms, in all cases, the suspected diagnosis was not rabies at first. In four cases, transmission occurred by marmosets ( Callithrix jacchus ), one by a hematophagous bat ( Desmodus rotundus ), and another by a domestic dog, though the identified viral strain was sylvatic. All patients died. Conclusion: Rabies in Cear á is a wildlife-mediated disease of the most vulnerable rural populations. There is a need for ongoing integrated surveillance and control measures, information and education campaigns, and professional training, especially focusing on wildlife-mediated rabies. An integrated One Health approach - as exemplified by the presented rabies control program in Cear á - is critical for human rabies elimination. with fever and pain in the arm but was taken to the local hospital only on the following day. The pediatrician prescribed antipyretic and analgesic drugs, and ice compresses. He did not ask about any history of animal contact. In the subsequent three days, the boy remained with moderate fever, and lack of appetite. On 26th February, he presented episodes of frequent vomiting. The day after, he was taken again to the local hospital. Another day later, his general condition worsened. Until now, diagnosis the diagnosis was dengue fever. On 29th February, the physicians suspected meningitis and transferred him to the reference hospital in the region in Barbalha municipality. There, rabies was suspected for the first time, and family members were asked about animal contacts, which was confirmed to be happened about 27 days ago. The Recife Protocol was implemented immediately, but the boy died on 12th March Intervention: The state rapid response team immediately conducted active case finding of individuals who had contact with saliva of the boy, or with the animal. The grandmother had contact with both, and on 4th March developed f","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82110896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"My experience with One Health: between realism and optimism","authors":"Alejandro Gaviria","doi":"10.20517/OHIR.2020.001","DOIUrl":"https://doi.org/10.20517/OHIR.2020.001","url":null,"abstract":"© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79146203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable control of tungiasis in rural Nigeria: a case for One Health","authors":"J. Heukelbach, L. Ariza, Rukayat Queen Adegbola, U. Ugbomoiko","doi":"10.20517/OHIR.2021.01","DOIUrl":"https://doi.org/10.20517/OHIR.2021.01","url":null,"abstract":"© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73792979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The COVID-19 pandemic and the disaster of the response of a right-wing government in Brazil","authors":"L. Kerr, Carl Kendall","doi":"10.20517/ohir.2021.11","DOIUrl":"https://doi.org/10.20517/ohir.2021.11","url":null,"abstract":"","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77361594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stability of West Nile virus in lysis solution and its implication on One Health","authors":"Jesse J. C. Erandio, M. Debboun","doi":"10.20517/ohir.2021.06","DOIUrl":"https://doi.org/10.20517/ohir.2021.06","url":null,"abstract":"","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"62 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72630103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Typhus in the Warsaw Ghetto 1940-1942: how an epidemic increased exponentially, was abated and eventually disappeared","authors":"H. Feldmeier","doi":"10.20517/ohir.2021.03","DOIUrl":"https://doi.org/10.20517/ohir.2021.03","url":null,"abstract":"","PeriodicalId":94377,"journal":{"name":"One health & implementation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89344811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}