Journal of biomedical science and research最新文献

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Effective Moderate-To-Vigorous Physical Activity (MVPA) During Evening Period for Lifestyle-Related Diseases 晚间适度至剧烈运动 (MVPA) 有效预防生活方式相关疾病
Journal of biomedical science and research Pub Date : 2024-07-22 DOI: 10.36266/jbsr/188
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引用次数: 0
Cardio-Reno-Protective Key Agents Such as Mineralocorticoid Receptor Antagonists (MRA) And Angiotensin Receptor-Neprilysin Inhibition (ARNI) 矿物质皮质激素受体拮抗剂 (MRA) 和血管紧张素受体-奈普利酶抑制剂 (ARNI) 等心脏修复保护关键药物
Journal of biomedical science and research Pub Date : 2024-07-13 DOI: 10.36266/jbsr/187
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引用次数: 0
Roasting Effects on Radical Scavenging Activity of an Edible Brown Alga, Hijikia Fusiformis (Hijiki) 焙烧对食用褐藻 Hijikia Fusiformis (Hijiki) 清除辐射活性的影响
Journal of biomedical science and research Pub Date : 2023-12-20 DOI: 10.36266/jbsr/182
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引用次数: 0
Holt-Winters Forecast: Machine Performance Check Output Variation 冬季预报:机器性能检查输出变化
Journal of biomedical science and research Pub Date : 2023-06-15 DOI: 10.36266/jbsr/173
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引用次数: 0
Maternal Serum Progesterone And Estradiol During Pregnancy And Childbirth –What Has The Literature Taught Us So Far? 妊娠和分娩期间的母体血清黄体酮和雌二醇-迄今为止,文献告诉了我们什么?
Journal of biomedical science and research Pub Date : 2023-02-08 DOI: 10.36266/jbsr/169
{"title":"Maternal Serum Progesterone And Estradiol During Pregnancy And Childbirth –What Has The Literature Taught Us So Far?","authors":"","doi":"10.36266/jbsr/169","DOIUrl":"https://doi.org/10.36266/jbsr/169","url":null,"abstract":"","PeriodicalId":93774,"journal":{"name":"Journal of biomedical science and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73911181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Implementation of Oncolytic Viruses for Cancer Immunotherapy: Review of Challenges and Current Clinical Trials. 溶瘤病毒在癌症免疫治疗中的治疗实施:挑战和当前临床试验的回顾。
Journal of biomedical science and research Pub Date : 2022-01-01 Epub Date: 2022-10-20 DOI: 10.36266/JBSR/164
X Wang, H M Maeng, J Lee, C Xie
{"title":"Therapeutic Implementation of Oncolytic Viruses for Cancer Immunotherapy: Review of Challenges and Current Clinical Trials.","authors":"X Wang,&nbsp;H M Maeng,&nbsp;J Lee,&nbsp;C Xie","doi":"10.36266/JBSR/164","DOIUrl":"https://doi.org/10.36266/JBSR/164","url":null,"abstract":"<p><p>The development of cancer therapeutics has evolved from general targets with radiation and chemotherapy and shifted toward treatments with a more specific mechanism of action such as small molecule kinase inhibitors, monoclonal antibodies against tumor antigens, or checkpoint inhibitors. Recently, oncolytic viruses (OVs) have come to the forefront as a viable option for cancer immunotherapy, especially for \"cold\" tumors, which are known to inhabit an immunologically suppressive tumor microenvironment. Desired characteristics of viruses are selected through genetic attenuation of uncontrolled virulence, and some genes are replaced with ones that enhance conditional viral replication within tumor cells. Treatment with OVs must overcome various hurdles such as premature viral suppression by the host's immune system and the dense stromal barrier. Currently, clinical studies investigate the efficacy of OVs in conjunction with various anti-cancer therapeutics, including radiotherapy, chemotherapy, immune checkpoint inhibitors, and monoclonal antibodies. Thus, future research should explore how cancer therapeutics work synergistically with certain OVs in order to create more effective combination therapies and improve patient outcomes.</p>","PeriodicalId":93774,"journal":{"name":"Journal of biomedical science and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40489051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
What Is The Mechanism That Causes The Drop Of TheMaximal Heart Rate During Normal Aging? 正常衰老过程中最大心率下降的机制是什么?
Journal of biomedical science and research Pub Date : 2021-09-12 DOI: 10.36266/jbsr/146
{"title":"What Is The Mechanism That Causes The Drop Of TheMaximal Heart Rate During Normal Aging?","authors":"","doi":"10.36266/jbsr/146","DOIUrl":"https://doi.org/10.36266/jbsr/146","url":null,"abstract":"","PeriodicalId":93774,"journal":{"name":"Journal of biomedical science and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80917614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Anti-Ageing Potential of aNew Dermocosmetic Containing Retinoids Mix Through In Vitro Models 通过体外模型评价含类维生素a混合物的新型皮肤化妆品的抗衰老潜力
Journal of biomedical science and research Pub Date : 2021-08-12 DOI: 10.36266/jbsr/149
{"title":"Evaluation of the Anti-Ageing Potential of aNew Dermocosmetic Containing Retinoids Mix Through In Vitro Models","authors":"","doi":"10.36266/jbsr/149","DOIUrl":"https://doi.org/10.36266/jbsr/149","url":null,"abstract":"","PeriodicalId":93774,"journal":{"name":"Journal of biomedical science and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91032257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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