2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)最新文献

{"title":"Novel Method and Device for Delivery and Retention of Intrauterine Devices in the Immediate Postpartum Period: Pilot Baboon Feasibility Study","authors":"Etse-Oghena Y. Campbell, Christopher G. Rylander, L. Thaxton, M. Y. Williams-Brown","doi":"10.1115/dmd2020-9049","DOIUrl":"https://doi.org/10.1115/dmd2020-9049","url":null,"abstract":"\u0000 The immediate post-partum period offers a convenient time to have an intrauterine device placed because of the co-location of a non-pregnant woman and her clinician; however, this practice is associated with increased expulsion rates of up to 30%, compared with a 3% expulsion rate for interval insertions. This paper presents a device and method to improve intrauterine device delivery and retention in the immediate postpartum period. This initial feasibility study illustrates that it is possible to temporarily tether a commercially available intrauterine device within the uterus of an immediately postpartum baboon. The results indicate this device and method are technically feasible, but further studies will be needed to evaluate safety and efficacy in reducing expulsion rates.","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85999893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible Circuit Board Package Embedded With Multi-Stack Dies","authors":"N. Ueta, S. Sato, Masakazu Sato, Nakao Yoshio, Joshua P. Magnuson, R. Ishizuka","doi":"10.1115/dmd2020-9032","DOIUrl":"https://doi.org/10.1115/dmd2020-9032","url":null,"abstract":"\u0000 Miniaturization of electronics modules is always required for various medical applications including wearable technology, such as hearing aids, and implantable devices. Many types of high-density packaging technologies, such as package-on-package, bare-die stack, flex folded package and Through Si Via (TSV) technologies, have been proposed and used to fulfill the request. Among them, embedded die technology is one of the promising technologies to realize miniaturization and high-density packaging. We have developed WABE™ (wafer and board level device embedded) technology for embedding dies into multilayer flexible printed circuit (FPC) boards. The WABE package is comprised of thin dies (85 μm thickness), multi-layer polyimide, adhesive films and conductive paste. The dies are sandwiched by polyimide films with Cu circuits (FPCs). The conductive paste provides electrical connections between the layers as well as the layer and embedded die. First, each FPC layer is fabricated individually, and via holes are filled with conductive paste, and the dies are mounted on certain layers. Then, all layers undergo a one-step co-lamination process, and they are pressed to cure the adhesive material and conductive paste at the same time. This WABE technology has enabled multiple dies to be embedded by the one-step lamination process. Even if multiple dies are embedded, the footprint of a package can be reduced drastically by embedding multiple dies vertically in stacks. This paper describes the details of the results of fabricating a test vehicle with six embedded dies (three-dies in two stacks side-by-side). The fabricated test vehicle had 14 copper layers with less than 0.9 mm thickness. This paper also reports the results of various reliability testing on the package. These results were obtained by electrical measurements of daisy chain patterns formed between some of the layers. The fabricated test vehicle showed high reliability based on the results of a moisture and heat test and heat-shock test. These results show that the WABE technology to embed multiple dies vertically in polyimide film is one of the most promising packaging technologies to significantly miniaturize electronic circuits such as medical electronics.","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89598688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of a Modular Cost-Effective Robot Arm for Increased Dexterity in Laparoscopic Surgery","authors":"J. Lowery, C. Nelson","doi":"10.1115/dmd2020-9010","DOIUrl":"https://doi.org/10.1115/dmd2020-9010","url":null,"abstract":"\u0000 This paper outlines the design of a reconfigurable, partially disposable, tendon-driven robotic arm for providing assistance in laparoscopic surgery. The rationale for its development and design objectives are provided, followed by a description of its mechanical design. Kinematic simulations to assess workspace are presented, and a first-stage assessment of the functionality of a prototype using a custom test bench is also included.","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77626128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selectively Compliant Annuloplasty Ring to Enable Annular Dynamics in Mitral Valve Repair Evaluated by In-Vitro Stereovision","authors":"Samuel Frishman, Annabel M. Imbrie-Moore, M. Cutkosky, Ali Kight, I. Pirozzi, Michael J Paulsen, J. Woo","doi":"10.1115/dmd2020-9034","DOIUrl":"https://doi.org/10.1115/dmd2020-9034","url":null,"abstract":"\u0000 Mitral valve (MV) annular dynamics are critical to the long term efficacy of MV repair. Today’s annuloplasty rings, used to restore MV function, impose significant constraints on the motion profile of the MV annulus. We present a selectively compliant ring that provides sufficient stiffness to stabilize a diseased annulus while allowing physiological annular dynamics. Ring design is informed by a finite element analysis and experimentally evaluated with in-vitro stereophotogrammetry. We compare the ring dynamics to commercially available semi-rigid rings as well as values found in literature for healthy annuli. The results demonstrate that motion of the selectively compliant ring is significantly closer to that of a healthy annulus based on standard metrics that define MV annular movement. Specifically, the metrics for the new ring compare to those in literature as follows: change in orifice area 12.5 ± 3% vs.10 ± 2%; change in anterior-posterior diam. 5.4 ± 0.3% vs. 7 ± 1%; change in inter-commissural diam. 6.6 ± 1.3% vs. 5 ± 1%.","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85697974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Precise Scale-Up Method to Predict Particle Delivered Dose in a Human Respiratory System Using Rat Deposition Data: An In Silico Study","authors":"Hamideh Hayati, Yu Feng","doi":"10.1115/dmd2020-9060","DOIUrl":"https://doi.org/10.1115/dmd2020-9060","url":null,"abstract":"\u0000 As surrogates to human beings, rats are used occasionally to study the therapeutic impact of inhaled pulmonary drug particles in microscale. To speculate human responses from rat studies, scale-up factors are widely used to extrapolate particle lung deposition from rat to human. However, available scale-up methods are highly simplified and not accurate, because they directly use the human-to-rat ratios of body weights (RBW) or lung surface areas (RSA) as the scale-up factor. To find a precise scale-up strategy, an experimentally validated Computational Fluid-Particle Dynamics (CFPD) was employed to simulate the transport and deposition of microparticles in both human and rate respiratory systems, which encompasses the pulmonary routes from mouth/nose to airways up to Generation 17 (G17) for human and G23 for the rat. Microparticles with the same range of Stk/Fr were injected into both models with the airflow at resting conditions. Numerical results indicate that particles (with the size ranging from 1 to 13 μm for humans and 0.6 to 6 μm for rat) have similar deposition pattern (DP) and deposition fraction (DF) in both models, which are resulted from both inertial impaction and gravitational sedimentation effects. A novel correlation is proposed to predict DFs in both human and rat respiratory systems as a function of the ratio of Stokes number to Froude number (Stk/Fr). Using the correlation as the novel scale-up tool, inter-species extrapolations can be precisely done on predicting particle depositions in human respiratory systems based on the deposition data in rats obtained from animal studies.","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79792150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimizing cotton ball retention in neurological procedures.","authors":"Raphael Bechtold, Benjamin Garlow, Renee Liu, Arushi Tandon, Alexandra Szewc, William Zhu, Olivia Musmanno, Noah Gorelick, Ian Suk, Judy Huang, Henry Brem, Amir Manbachi, George Coles","doi":"10.1115/dmd2020-9042","DOIUrl":"10.1115/dmd2020-9042","url":null,"abstract":"<p><p>Neurosurgical operations are long and intensive medical procedures, during which the surgeon must constantly have an unobscured view of the brain in order to be able to properly operate, and thus must use a variety of tools to clear obstructions (like blood and fluid) from the operating area. Currently, cotton balls are the most versatile and effective option to accomplish this as they absorb fluids, are soft enough to safely manipulate the brain, act as a barrier between other tools and the brain, and function as a spacer to keep anatomies of the brain open and visible during the operation. While cotton balls allow neurosurgeons to effectively improve visibility of the operating area, they may also be accidentally left in the brain upon completion of the surgery. This can lead to a wide range of post-operative risks including dangerous immune responses, additional medical care or surgical operations, and even death. This project seeks to develop a unique medical device that utilizes ultrasound technology in order to minimize cotton retention after neurosurgical procedures in order to reduce undesired post-operative risks, and maximize visibility.</p>","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75972014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DEVELOPMENT OF A PORTABLE BLOOD POTASSIUM MONITORING DEVICE FOR DIALYSIS PATIENTS.","authors":"Parth Vora, Miguel Inserni, Alan Lai, Maya M Lapinski, Justin Wang, Min Jae Kim, Diane Lee, Rebecca Yu, Amir Manbachi, Mohamed G Atta","doi":"10.1115/dmd2020-9066","DOIUrl":"10.1115/dmd2020-9066","url":null,"abstract":"<p><p>Approximately 500,000 dialysis patients in America are at a high risk of hyperkalemia, a condition where blood potassium becomes elevated above normal levels. Hyperkalemia is extremely dangerous, as it can result in severe cardiac complications if untreated. Hyperkalemia may be silent or present vague symptoms until those complications develop, at which point patients require emergency medical care. However, if patients have the ability to measure their potassium levels at home, they could detect hyperkalemia before it reaches a dangerous stage, and seek preventative medical care to avoid severe complications. Therefore, we have designed a novel device allowing patients to measure their blood potassium levels at home. The workflow of our solution is as follows: (1) patients obtain a blood sample from a finger prick, (2) potassium concentration is measured with an ion specific electrode (ISE), and (3) the device displays their potassium levels and a recommended course of action based on their hyperkalemic risk. We validate our solution with three major tests. First, our portable ISE technology must accurately measure potassium concentration in blood samples. Second, appropriate lancet parameters (gauge and depth) to minimize hemolysis in capillary blood samples must be found to minimize falsely elevated readings. Third, device portability and ease of use must be evaluated using patient input, as these factors will affect patient compliance. We have validated the use of portable ISE technology to feasibly measure potassium, and we continue to collect data for our second and third tests.</p>","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76945642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"USDL: Inexpensive Medical Imaging Using Deep Learning Techniques and Ultrasound Technology.","authors":"Manish Balamurugan, Kathryn Chung, Venkat Kuppoor, Smruti Mahapatra, Aliaksei Pustavoitau, Amir Manbachi","doi":"10.1115/dmd2020-9109","DOIUrl":"10.1115/dmd2020-9109","url":null,"abstract":"<p><p>In this study, we present USDL, a novel model that employs deep learning algorithms in order to reconstruct and enhance corrupted ultrasound images. We utilize an unsupervised neural network called an autoencoder which works by compressing its input into a latent-space representation and then reconstructing the output from this representation. We trained our model on a dataset that compromises of 15,700 <i>in vivo</i> images of the neck, wrist, elbow, and knee vasculature and compared the quality of the images generated using the structural similarity index (SSIM) and peak to noise ratio (PSNR). In closely simulated conditions, the architecture exhibited an average reconstruction accuracy of 90% as indicated by our SSIM. Our study demonstrates that USDL outperforms state of the art image enhancement and reconstruction techniques in both image quality and computational complexity, while maintaining the architecture efficiency.</p>","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89179003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Evaluation of Sensing Technologies to Measure Intraoperative Leg Length for Total Hip Arthroplasty.","authors":"Akash Chaurasia, Jerry Yan, Robert Li, Kate McCarren, Claire State, Hannah Takasuka, Evan Bender, Aditi Jithendra, Julius K Oni, Amir Manbachi","doi":"10.1115/dmd2020-9056","DOIUrl":"10.1115/dmd2020-9056","url":null,"abstract":"<p><p>Total hip arthroplasty (THA) procedures have been identified as high-volume procedures with growing prevalence. During the procedure, orthopedic surgeons largely rely solely on qualitative assessment to ensure an excessive limb length discrepancy (LLD) is not introduced from the implant selection. LLD can result in back pain and gait complications, with some cases of LLD requiring a revision procedure to mitigate. To address this issue, we evaluated several methods of sensing distance intraoperatively to determine the best approach to measure leg length during the THA procedure. A testing setup using a sawbones model of hip anatomy in the decubitus position was used as a simulation of the THA procedure to test the accuracy of each of the sensing modalities.</p>","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77014621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DEVELOPMENT OF VOICE-CONTROLLED SMART SURGICAL BED.","authors":"Jeong Hun Kim, Richard Um, Nicholas Theodore, Rajiv Iyer, Amir Manbachi","doi":"10.1115/dmd2020-9065","DOIUrl":"10.1115/dmd2020-9065","url":null,"abstract":"<p><p>Wasted time in the operating room results in higher operating costs and greater post-operative complications. One effective way to reduce operation time is automating basic processes that occur during surgery. Given the rise of smart-home devices, implementation of virtual assistants became a feasible solution in many medical settings. With a consumer smart-home device and off-the-shelf components, we engineered a voice-controlled smart surgical bed that adjusts the bed configuration via a voice input. The resulting device is expected to optimize human resources and reduce surgical site infection by eliminating the need of a traditional touch control mechanism. Future work is needed to develop its proprietary hardware and software, and continuous collaboration with medical personnel to bring this device into market.</p>","PeriodicalId":93509,"journal":{"name":"2020 Design of Medical Devices Conference (DMD 2020). Design of Medical Devices Conferences (2020 : Minneapolis, Minn.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73243211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}