American journal of otolaryngology and head and neck surgery最新文献

{"title":"Right Sided Sphenoid Fungal Sinusitis Presenting with Contralateral Abducens Paralysis: A Rare Case Report","authors":"Çelebi Nk, G. M, Deveci Hs","doi":"10.25107/2640-6640-v5-id1214","DOIUrl":"https://doi.org/10.25107/2640-6640-v5-id1214","url":null,"abstract":"Abstract Isolated sphenoid sinus disease can be difficult to diagnose and treat due to the non-specificity of their symptoms and to the likelihood that these pathologies can present late with complications. For these reasons, significant delays in the diagnosis and treatment of the patient may happen. In addition, due to the proximity of the sphenoid sinus to vital structures such as the optic nerve, internal carotid artery, cavernous sinus and cranial nerves, any delay in treatment has the potential to lead to catastrophic outcomes, which is why swift diagnosis and early treatment are of the essence. In the differential diagnosis of isolated sixth cranial nerve palsy, sphenoid sinus pathologies must be kept in mind and the patients worked up with CT and/or MRI. Swift diagnosis and treatment before intracranial progression occurs could prevent severe complications. In our case report, we present a patient with isolated right sphenoid sinus aspergilloma (fungus ball) presenting with hemicranial headache and contralateral 6th cranial nerve involvement. In the literature, ipsilateral 6th cranial nerve involvement secondary to sphenoid sinusitis has been commonly reported, however so far only two cases of contralateral cranial nerve involvement have been reported, therefore our case represents a very rare presentation of a rare pathology. The patient has been operated with an endoscopic transnasal approach and in her postoperative follow up, lateral gaze function of the left eye has been observed to be significantly improved. Our case underlines the importance of considering sphenoid sinus aspergillomas in the differential diagnosis of patients presenting with unexplained cranial nerve pathologies, especially in the presence of headache, and the importance of early radiological studies and early operative treatment in these patients.","PeriodicalId":93410,"journal":{"name":"American journal of otolaryngology and head and neck surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48333454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Martial Arts and Shooting Training Have Different Effects on Auditory Fine Structure Processing Ability - Evidence from Behavioral Tests and fMRI","authors":"Yu Ding, Keying Zhang, Liang Li, Chunmei Cao","doi":"10.25107/2640-6640-v5-id1188","DOIUrl":"https://doi.org/10.25107/2640-6640-v5-id1188","url":null,"abstract":"In this work, we explore the influence of traditional martial arts and shooting training on the ability of auditory Temporal Fine Structure (TFS) processing. Twenty-five college students participated in the experiment, including 8 traditional martial arts practitioners, 8 high-level shooting athletes, and 9 control groups without any regular exercise habits. The BIC (break in interaural correlation) delay threshold and TFS1 test were used to evaluate the transient storage capacity and sensitivity of TFS, respectively. An fMRI test was performed after the behavioral tests. The results found that the traditional martial arts group had stronger TFS sensitivity, while the shooting group had stronger TFS storage capacity and the performance of the behavioral tests of the shooting group is related to the fALFF value of the brain areas of interest. The effects of exercise training on hearing ability may have a specific neural basis and can be used for early intervention in potential hearing impairment.","PeriodicalId":93410,"journal":{"name":"American journal of otolaryngology and head and neck surgery","volume":"23 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41309408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Surgeons Use Parathyroid Hormone Levels as Predictive Value in Parathyroid Adenomas?","authors":"M. Tokoçin, Talar Vartanoglu Aktokmakyan, Ahmet Guray Durmaz, O. Tokoçin, H. Bilge, E. Yavuz","doi":"10.25107/2640-6640-v4-id1128","DOIUrl":"https://doi.org/10.25107/2640-6640-v4-id1128","url":null,"abstract":"Aim: Previous studies using different methods for PTH measurement have found a mild to moderate correlation between iPTH and gland weight. The aim of this study was to describe the relationship between parathyroid hormone and parathyroid adenoma volume, in patients with parathyroid adenomas as predictive value. Material and Methods: The multicenteric study was prepared by retrospectively collecting data from 244 patients with parathyroid adenoma who underwent parathyroidectomy and followed up between 2010 and 2020. Results: Two hundred forty and four (female/male = 203/41) patients with a mean age of 51.41 [min-max: 17 to 88] years. The mean iPTH concentrations preoperatively were 584.27 ng/L [min-max: 18.9 to 5011ng/L]. The mean diameter of adenoma of patients was 2,865 mm3 [min-max: 0.119 to 42.3 mm3]. After parathyroidectomy, PTH values were reevaluated and found as 47.2 ng/L [min-max: 0.2 to 903 ng/L]. In the patients with large parathyroid adenoma volume, preoperative PTH hormone values were statistically significantly higher (p=0.001). Conclusion: Our current study found a positive association between baseline iPTH levels and adenoma weight. These results suggest that serum iPTH level may be useful in predicting parathyroid adenoma volume.","PeriodicalId":93410,"journal":{"name":"American journal of otolaryngology and head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44992632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost Analysis of an Annual School-Based Pediatric Hearing Screening Program in Semi-Rural Kenya.","authors":"Nicole Kloosterman,&nbsp;Kevin N Griffith,&nbsp;Kristen Yancey,&nbsp;Asitha Dl Jayawardena,&nbsp;James Netterville","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Approximately 8.9 million children in Sub-Saharan Africa have disabling hearing loss, accounting for 11% of the global child healthcare hearing costs. For children living in Low- and Middle-Income Countries (LMICs), 75% of hearing loss is preventable.</p><p><strong>Methods: </strong>We evaluate the overall intervention and expansion costs of a humanitarian, pediatric hearing health and screening program in Malindi, Kilifi County, Kenya. A cost analysis is conducted from the provider perspective, identifying the mean cost incurred for each case of newly identified hearing loss. Estimates were made for 3 different cost scenarios. A one-way sensitivity analysis and probabilistic sensitivity analysis using Monte Carlo simulation determined the impact of variations in individual cost parameters. These results were used to project scale-up costs to achieve sub-county expansion of the program.</p><p><strong>Results: </strong>155 children ages 5 to 16 years old were screened, of which 5.8% were diagnosed with hearing impairment. The total cost for implementation in four schools was $6,783 USD, thus a mean cost of $212 per diagnosis of hearing loss. The highest proportion of costs were recurrent costs of resident travel (27.9%), capital costs for providing audiometric testing (25.3%), and equipment maintenance (18.7%). Expansion of an exclusively CHW-run program across all 77 primary public schools in Malindi is projected to be $130,573 (range $119,352 to $142,240).</p><p><strong>Conclusion: </strong>We provide relevant cost-estimation for an expansion of an intervention which identified higher than average rates of hearing loss. Humanitarian aid plays a key role in the sustainability and feasibility of expanding this program.</p>","PeriodicalId":93410,"journal":{"name":"American journal of otolaryngology and head and neck surgery","volume":"4 10","pages":"1161"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increase Cancer Risk in Patients with Primary Hyperparathyroidism","authors":"R. Arrangóiz, J. Sánchez-García, E. Moreno-Paquentín, D. CabaMolina, E. LuquedeLeón, F. Cordera, M. Múñoz","doi":"10.25107/2640-6640-V2-ID1051","DOIUrl":"https://doi.org/10.25107/2640-6640-V2-ID1051","url":null,"abstract":"Introduction: Primary Hyperparathyroidism (PHPT) affects at least 1 in 1000 individuals and its incidence increases with age, with a peak incidence in the seventh decade of life. It is the third most common endocrine diagnosis. Several studies have identified a relationship between PHPT and an increased risk of developing malignancies such as breast, skin, colon, rectal, thyroid, prostate, and kidney cancers. The aim of this study was to report a cohort of patients with PHPT with concomitant cancer and compared them with PHPT without cancer. Methods: Retrospective study from a prospectively kept database of patients with PHPT treated by our group between January 2015 and July 2017. The operation performed by our group is, a minimally invasive radio-guided parathyroidectomy, which entails a bilateral neck exploration through a two-centimeter incision. The patients’ characteristics were obtained and analyzed from the electronic medical records. Patients without complete medical records were not included in our study. All data were collected in a non-identifiable fashion in accordance with the principles outlined in the declaration of Helsinki and as required for our institutional review board approval. Results and Discussion: A total of 63 patients with PHPT were included in our study. Eighty percent of our patients were females; the mean age at diagnosis was 56.7 years (range: 29 years to 77 years). There were 23 patients with concomitant cancer (36.5% of the cases). The most frequently encountered malignancy was breast cancer in 14.3% of the cases (nine patients), thyroid cancer 7.9% (five patients), and skin cancer 6.3% (two patients with melanoma, one with basal-cell carcinoma and another one with squamous cell cancer). We did not identify a clinical or statistical difference between the two groups. The patients’ demographics were very similar: gender (p=0.8), age (p=0.6), preoperative calcium levels (p=0.3), preoperative PTH levels (p=0.2), preoperative vitamin D levels (p=0.5) and preoperative urinary calcium levels (p=0.5). Conclusion: The available evidence at this time suggests a possible correlation between PHPT and malignancy. It remains to be clarified whether the risk is due to genetic predisposition to tumor development or a physiological associative effect. We recommend discussing with patients with a diagnosis of PHPT who are considering undergoing a parathyroidectomy about the possible increased risk of cancer seen in patients with PHPT. More studies are needed to determinate the exact relationship between the PHPT and the risk of developing cancer.","PeriodicalId":93410,"journal":{"name":"American journal of otolaryngology and head and neck surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44889466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Breast Cancer Associated with Primary Hyperparathyroidism?","authors":"R. Arrangóiz, D Margain-Treviño, J. Sánchez-García, E Moreno-Paquentin, D Caba-Molina, E. Luque-de-León, F. Cordera, M. Múñoz, E Cruz-González","doi":"10.25107/2640-6640-v2-id1033","DOIUrl":"https://doi.org/10.25107/2640-6640-v2-id1033","url":null,"abstract":"Introduction: Breast cancer is the most common cancer in women and the second leading cause of cancer-related deaths across the world. Hypercalcemia is known to occur in up to 20% to 30% of the patients with a cancer diagnosis at some point during the course of their illness. Breast cancer is one of the malignancies most commonly associated with hypercalcemia. Primary Hyperparathyroidism (PHPT) has been associated with an increased risk of developing breast cancer compared with patients without PHTP. Little is known about the underlying risk factors. The aim of our study is to describe a cohort of patients with PHPT and breast cancer. Methods: Retrospective study from a prospectively kept database of patients with PHPT treated by our group between January 2015 and July 2017 who had been diagnosed with breast cancer. The patients’ characteristics were obtained and analysed from the electronic medical records. Patients without complete medical records were not included in our study. All data were collected in a nonidentifiable fashion in accordance with the principles outlined in the Declaration of Helsinki and as required for our institutional review board approval. Results and Discussion: A total of ten patients were included in this study, all patients were female; the mean age was 59.2 years. The mean preoperative calcium, PTH and vitamin D were 10.1 mg/ dL, 99.6 pg/mL and 25.5 ng/dL, respectively. A significant decrease of intraoperative PTH and postoperative calcium and PTH were achieved after surgical treatment. Pathology reported that 50% of the cases were secondary to a single adenoma (five patients) and 50% (five patients) of the cases had parathyroid gland hyperplasia. Unilateral (70%), stages I or II (70%), invasive ductal breast carcinoma (90%) were the most common diagnosis. The immunohistochemical status reported that 80% of patients had hormone receptor positive breast cancer. The mean time between breast cancer and PHPT operations was 89.5 months. Conclusion: Breast cancer and PHPT share several common characteristics, which has led to the postulation of common etiological pathways. However, the exact pathogenesis and the relationship between breast cancers and PHPT still remains unclear. PHTP should be considered as a possible cause of hypercalcemia in patients with non-aggressive breast cancer. We suggest that serum PTH should be determined in all breast cancer patients with increased serum calcium concentration, especially in those with no evidence of metastatic disease. Introduction Breast cancer is the third most common cancer in the world and in the United States of America it is the leading cause of cancer in women (except for skin cancer) and the second most common cause of cancer related deaths. Currently, the average risk of a woman born in the USA developing breast cancer at some point in her lifetime is approximately 12% [1]. Hypercalcemia is a known metabolic complication of several malignancies including breast cancer","PeriodicalId":93410,"journal":{"name":"American journal of otolaryngology and head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44156818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Arytenoid Abduction Lateropexy for the Treatment of Bilateral Vocal Cord Paralysis in Early Childhood: Case Report","authors":"Sztanó B, Bach A, Matievics V, Erdélyi E, Rovó L","doi":"10.25107/AJOHNS.V1-ID1011","DOIUrl":"https://doi.org/10.25107/AJOHNS.V1-ID1011","url":null,"abstract":"Objectives: The treatment of bilateral vocal cord paralysis in early childhood is really challenging even now a days. One of the treatment options is endoscopic arytenoid abduction lateropexy; a reversible simple suture vocal cord lateralizing technique, the arytenoid cartilage is directly lateralized to normal abducted position. Authors introduce a case of a successfully treated toddler. Methods: The 2.5 years old boy had noisy breathing and dyspnea on exertion since delivery. Laryngo-tracheoscopy revealed bilateral vocal cord paralysis. Unilateral, left-sided endoscopic arytenoid abduction lateropexy was performed with supraglottic jet ventilation. Results: He remained intubated for 3 with an uncuffed tracheal tube. After extubation, no dyspnea or swallowing disorder occurred. During the follow-up laryngo-tracheoscopies, clinical growth charts and voice analysis showed satisfactory functional results. Conclusions: The endoscopic arytenoid abduction lateropexy is a minimally invasive, quick, reversible endoscopic glottis enlarging procedure, which might be a favorable solution for neonatal bilateral vocal cord paralysis even in early childhood. It provides immediately wide airway without any permanent damage to voice production.","PeriodicalId":93410,"journal":{"name":"American journal of otolaryngology and head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69299017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}