Kou qiang yi xue yan jiu = Journal of oral science research最新文献

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Effect of Pregnancy on TMJ Nociception in Rats. 妊娠对大鼠颞颌关节痛觉的影响。

Kou qiang yi xue yan jiu = Journal of oral science research Pub Date : 2018-03-01 DOI: 10.13701/j.cnki.kqyxyj.2018.03.029

Mikhail Umorin, L. Bellinger, P. Kramer

{"title":"Effect of Pregnancy on TMJ Nociception in Rats.","authors":"Mikhail Umorin, L. Bellinger, P. Kramer","doi":"10.13701/j.cnki.kqyxyj.2018.03.029","DOIUrl":"https://doi.org/10.13701/j.cnki.kqyxyj.2018.03.029","url":null,"abstract":"Objective\u0000Does TMJ nociception, as measured by a behavioral assay, differ during pregnancy, potentially due to the effect of sex steroids?\u0000\u0000\u0000Methods\u0000Thirty - two Sprague Dawlcy rats were randomly allocated to either mid- (EH 11) or late- (EH 17) pregnancy groups. The animals within each group were further allocated to a saline or CFA treatment. At EH 11 or EH 17, the animals were injected bilaterally into TMJ with either saline (15 μL.) or 1 μg/μL CFA (15 μL). Nociception was measured with a feeding assay (pellet recording) and analyzed by comparing in-tra-meal rates using a distance-based permutation method.\u0000\u0000\u0000Results\u0000CFA injection resulted in the animals eating longer in both the mid - pregnant and late-pregnant groups. Plasma estradiol was higher in the late - pregnant group versus the mid - pregnant group. Importantly, the CFA injected late-pregnant group ate for a shorter amount of time (i. e., shorter meal rate) than the CFA injected rats at mid - pregnancy.\u0000\u0000\u0000Conclusion\u0000The reduced nociceptive response (shorter meal rate) in the CFA injected late - pregnant group may be due to greater estradiol versus the CFA injected mid - pregnancy rats. Thus, one potential reason why women report fewer TMJ symptoms during pregnancy is the higher level of circulating estradiol.","PeriodicalId":92817,"journal":{"name":"Kou qiang yi xue yan jiu = Journal of oral science research","volume":"34 3 1","pages":"332-338"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42555221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of TNF-α,IL-1β and LPS Levels in the Gingival Crevicular Fluid of a Rat Model of Diabetes Mellitus and Periodontitis 糖尿病和牙周炎模型大鼠龈沟液中TNF-α、IL-1β和LPS水平的研究

Kou qiang yi xue yan jiu = Journal of oral science research Pub Date : 2014-01-01 DOI: 10.1155/2013/156798

Jiang Zhu-lin

引用次数: 42

Synergistic Effects of Mechanical Pressure and Estrogen on the Proliferation and Alkaline Phosphatase Activity of Mandibular Condylar Chondrocytes 机械压力和雌激素对下颌髁软骨细胞增殖和碱性磷酸酶活性的协同作用

Kou qiang yi xue yan jiu = Journal of oral science research Pub Date : 2010-01-01 DOI: 10.1007/978-3-642-14515-5_290

Min Zhang, An-Hui Wang, Yongjin Chen, Faming Chen

引用次数: 0