Forensic science and criminology最新文献

{"title":"The status of Chinese handwriting identification and the improvement of methodologies","authors":"Guanqing Wang","doi":"10.15761/FSC.1000129","DOIUrl":"https://doi.org/10.15761/FSC.1000129","url":null,"abstract":"","PeriodicalId":92360,"journal":{"name":"Forensic science and criminology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67463469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-laboratory validation of a Δ9-tetrahydrocannabinol LC-MS/MS test kit designed for quantifying THC and marijuana metabolites in blood.","authors":"Amy L Patton,&nbsp;Joseph O Jones,&nbsp;Anne Nord,&nbsp;D W Eversole,&nbsp;Erin E Feazell,&nbsp;Kristen Mauldin,&nbsp;Lingyun Li,&nbsp;Lee D Williams,&nbsp;Shasha Bai,&nbsp;Kermit Channell,&nbsp;Gregory Endres,&nbsp;Matthew Gamette,&nbsp;Jeffery H Moran","doi":"10.15761/FSC.1000125","DOIUrl":"https://doi.org/10.15761/FSC.1000125","url":null,"abstract":"<p><p>Marijuana legalization has increased the demand for testing of Δ9-tetrahydrocannabinol (THC) and THC metabolites. The THC ToxBox^® test kit (THC ToxBox^®) is commercially available and supports high-throughput LC-MS/MS analytical methods designed to quantify low levels of THC and THC metabolites in blood. The purpose of this study is to determine if this new test kit meets the rigors of laboratory accreditation and produces equivalent results across six states- and locally-funded laboratories. Each laboratory followed internal method validation procedures established for their clinical (CLIA) or international (ISO17025) accreditation program. Test performance indicators included accuracy, precision, measurement of uncertainty, calibration models, reportable range, sensitivity, specificity, carryover, interference, ion suppression/enhancement and analyte stability. Analytes and interferents were resolved within the 6-min analytical runtime, and the 48-well plate pre-manufactured with calibrators, second source quality control material, and internal standards at precise concentrations allowed for simple and consistent sample preparation in less than one hour. Every laboratory successfully validated test kit procedures for forensic use. Differences in sensitivity were generally associated with the use of older equipment. Statistical analysis of results spanning reportable ranges show that laboratories with different instrument platforms produce equivalent results at levels sufficiently low enough to support per se limit testing of THC and THC metabolites (1-5 ng/mL). THC ToxBox^® represents a viable option for state- and locally-funded laboratories charged with investigating impaired driving cases involving marijuana use.</p>","PeriodicalId":92360,"journal":{"name":"Forensic science and criminology","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36269341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cell Wall Pigment Formation of in vitro Cultures of the Liverwort Ricciocarpos natans.","authors":"Siegmund Kunz, Hans Becker","doi":"10.1515/znc-1995-3-412","DOIUrl":"10.1515/znc-1995-3-412","url":null,"abstract":"<p><p>The liverwort Ricciocarpos natans has been cultivated on Gamborg B5 medium with different levels of ammonium, nitrate, phosphate and sucrose. The formation of the cell wall pigments riccionidin A and B was shown to be dependent on the level of these nutrients as well as on the intensity of light. A decrease in nitrogen supply (mainly nitrate) induced the formation of both wall pigments, whereas phosphate and high levels of sucrose inhibited the pigment synthesis. Decreasing the illumination rate led to lower anthocyanidin contents. Dedifferentiated cultures also produced wall pigments, but their amount was much lower compared to differentiated cultures.</p>","PeriodicalId":92360,"journal":{"name":"Forensic science and criminology","volume":"1 1","pages":"235-240"},"PeriodicalIF":0.0,"publicationDate":"2014-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/znc-1995-3-412","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89578498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}