Nuclear medicine and biomedical imaging最新文献

{"title":"Advanced magnetic resonance imaging and the contribution of 99mTc-tetrofosminbrain SPECT in the differential diagnosis of cerebral tumors","authors":"Tsitsia V, Valotassiou V, Kapsalaki E, Fountas K, Siasios I, Tzavara C, Theodorou K, G. P., Tsougos I","doi":"10.15761/nmbi.1000148","DOIUrl":"https://doi.org/10.15761/nmbi.1000148","url":null,"abstract":"","PeriodicalId":92271,"journal":{"name":"Nuclear medicine and biomedical imaging","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital breast tomosynthesis: a state-of-the-art review","authors":"Marcello Alessandro ORSI, Cellina M, Rosti C, Gibelli D, Belloni E, Oliva G","doi":"10.15761/nmbi.1000149","DOIUrl":"https://doi.org/10.15761/nmbi.1000149","url":null,"abstract":"Digital Breast Tomosynthesis (DBT) is an X-ray mammography technique where multiple low-dose projection images of the breast are reconstructed in multiple tomographic images creating a semi-3D mammogram. This enables the visualization of a sequential set of thin sections of the breast, overcoming the masking effect of overlying fibroglandular breast tissue, then improving carcinoma detection and reducing false-positive cases. This review aims at describing current DBT technique, analyzing DBT in clinical practice and providing an overview of published studies on clinical experience with DBT in the screening and diagnostic settings.","PeriodicalId":92271,"journal":{"name":"Nuclear medicine and biomedical imaging","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel approaches for quantitative electrogram analysis for intraprocedural guidance for catheter ablation: A case of a patient with persistent atrial fibrillation.","authors":"S P Arunachalam, S Kapa, S K Mulpuru, P A Friedman, E G Tolkacheva","doi":"10.15761/NMBI.1000121","DOIUrl":"10.15761/NMBI.1000121","url":null,"abstract":"<p><strong>Purpose: </strong>Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia that causes stroke affecting more than 2.3 million people in the US and is increasing in prevalence due to ageing population causing a new global epidemic. Catheter ablation with pulmonary vein isolation (PVI) to terminate AF is successful for paroxysmal AF but suffers limitations with persistent AF patients as current mapping methods cannot identify AF active substrates outside of PVI region. Recent evidences in the mechanistic understating of AF pathophysiology suggest that ectopic activity, localized re-entrant circuit with fibrillatory propagation and multiple circuit re-entries may all be involved in human AF. The authors developed novel electrogram analysis methods and validated using optical mapping data from isolated rabbit hearts to accurately identify rotor pivot points. The purpose of this study was to assess the feasibility of generating patient-specific 3D maps for intraprocedural guidance for catheter ablation using intracardiac electrograms from a persistent AF patient using novel electrogram analysis methods.</p><p><strong>Methods: </strong>A persistent AF patient with clinical appointment for AF ablation was recruited for this study with IRB approval. 1055 electrograms throughout the left and right atrium were obtained for offline analysis with the novel approaches such as multiscale entropy, multiscale frequency, recurrence period density entropy, kurtosis and empirical mode decomposition to generate patient specific 3D maps. 3D Shannon Entropy, Renyi Entropy and Dominant frequency maps were also generated for comparison purposes along with local activation time and complex fractionated electrogram analysis maps.</p><p><strong>Results: </strong>Patient specific 3D maps were obtained for each of the different approach. The 3D maps indicate potential active sites outside the PVI region. However, presence of rotors cannot be confirmed and validation of these approaches is required on a larger dataset.</p><p><strong>Conclusions: </strong>Conventional catheter mapping system can be used for generating patient specific 3D maps with short time series analysis using the novel approaches.</p>","PeriodicalId":92271,"journal":{"name":"Nuclear medicine and biomedical imaging","volume":"2 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35794071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is PSMA PET a necessity in oligo-metastatic recurrent prostate cancer?","authors":"A. Hampson, Bhavan Prasad Rai, N. Vasdev","doi":"10.15761/NMBI.1000146","DOIUrl":"https://doi.org/10.15761/NMBI.1000146","url":null,"abstract":"Received: September 14, 2018; Accepted: September 21, 2018; Published: September 27, 2018 Positron Emission Tomography (PET) nuclear imaging is vital in the process of diagnosing recurrence of prostate cancer following radical therapy. The conventional PET modality uses Choline based tracers (11C or 18F), a phospholipid precursor that becomes concentrated in areas of high cell division and thus highlights areas of malignancy. This is the current form of gold standard imaging for prostate cancer recurrence, however, multiple studies have found that it’s sensitivity and specificity vary significantly, with a reduced accuracy at PSA levels of less than 1ng/ml [1,2]. This can result in delays in salvage therapy or delayed diagnoses, and thus has driven research into alternative imaging modalities with the aim of improving patient care.","PeriodicalId":92271,"journal":{"name":"Nuclear medicine and biomedical imaging","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}