Martha Johnson, Mehmet Ates, Zikri Arslan, Ibrahim Farah, Coneliu Bogatu
{"title":"Assessment of Crystal Morphology on Uptake, Particle Dissolution, and Toxicity of Nanoscale Titanium Dioxide on <i>Artemia salina</i>.","authors":"Martha Johnson, Mehmet Ates, Zikri Arslan, Ibrahim Farah, Coneliu Bogatu","doi":"10.4018/JNN.2017010102","DOIUrl":"10.4018/JNN.2017010102","url":null,"abstract":"<p><p>Knowledge of nanomaterial toxicity is critical to avoid adverse effects on human and environment health. In this study, the influences of crystal morphology on physico-chemical and toxic properties of nanoscale TiO<sub>2</sub> (<i>n</i>-TiO<sub>2</sub>) were investigated. <i>Artemia salina</i> were exposed to anatase, rutile and mixture polymorphs of <i>n</i>-TiO<sub>2</sub> in seawater. Short-term (24 h) and long-term (96 h) exposures were conducted in 1, 10 and 100 mg/L suspensions of <i>n</i>-TiO<sub>2</sub> in the presence and absence of food. Anatase form had highest accumulation followed by mixture and rutile. Presence of food greatly reduced accumulation. <i>n</i>-TiO<sub>2</sub> dissolution was not significant in seawater (p<0.05) nor was influenced from crystal structure. Highest toxic effects occurred in 96h exposure in the order of anatase > mixture > rutile. Mortality and oxidative stress levels increased with increasing <i>n</i>-TiO<sub>2</sub> concentration and exposure time (p<0.05). Presence of food in the exposure medium alleviated the oxidative stress, indicating that deprivation from food could promote toxic effects of <i>n</i>-TiO<sub>2</sub> under long-term exposure.</p>","PeriodicalId":92250,"journal":{"name":"Journal of nanotoxicology and nanomedicine","volume":"2 1","pages":"11-27"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4018/JNN.2017010102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35736356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}