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Can Protein Restriction Set Up T Lymphocytes Favorably For Their Activation Against Pathogens Through Myc? 蛋白限制是否有利于T淋巴细胞通过Myc激活对抗病原体?
MOJ lymphology & phlebology Pub Date : 2018-11-16 DOI: 10.15406/MOJI.2018.06.00213
Jung-eun Lee
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引用次数: 0
Can Protein Restriction Set Up T Lymphocytes Favorably For Their Activation Against Pathogens Through Myc? 蛋白限制是否有利于T淋巴细胞通过Myc激活对抗病原体?
MOJ lymphology & phlebology Pub Date : 2017-01-01 Epub Date: 2017-08-09
Jung-Eun Lee
{"title":"Can Protein Restriction Set Up T Lymphocytes Favorably For Their Activation Against Pathogens Through Myc?","authors":"Jung-Eun Lee","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One area that presents a significant threat to global health is infectious diseases. With increasing prevalence of antibiotic-resistant bacteria [1], opportunistic infections are a growing concern for human societies. In 2009, there were 89,000 deaths caused by pneumonia, septicemia, and influenza virus in the United States alone [2]. Antibiotic-resistant bacteria increase the risk of secondary infection that is associated with many standard medical procedures such as organ transplantation, chemotherapy, dialysis, and elective surgery [1]. The deceleration of new drug discovery suggests that acute preventative strategies strengthening host immunity prior to such procedures are of strong interest. In this mini review, I will suggest a protein restriction-Myc signaling as a potential pharmacological target to boost the survival outcome following pathogenic bacterial infection.</p>","PeriodicalId":92105,"journal":{"name":"MOJ lymphology & phlebology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708585/pdf/nihms920421.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35220403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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