Laura Paulson, Dianne Thornhill, Jennifer Armstrong
{"title":"Clinic Follow up and Neurological Disability in Children Following Pregnancies Complicated by Preterm Rupture of Membranes and Preeclampsia.","authors":"Laura Paulson, Dianne Thornhill, Jennifer Armstrong","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Context: </strong>Preeclampsia and preterm premature rupture of membranes (PPROM) have been associated with perinatal brain injury. Despite a strong understanding of the relationships between preterm birth and neurologic deficits, and between PPROM and preeclampsia and preterm birth, the relationship between PPROM and preeclampsia and neurologic disability is not well characterized.</p><p><strong>Objective: </strong>We compared trends in neurologic deficits in children born to mothers with these conditions and described differences in patient characteristics among follow up visit attendance.</p><p><strong>Methods: </strong>We conducted a prospective cohort study of women with preeclampsia or PPROM. Neurologic deficits were assessed with the Pediatric Stroke Outcome Measure at follow up visits through age 10 years. Eighty nine of the 178 women enrolled completed at least one follow up. Results: Among children born >32 weeks, PPROM showed higher left and right sided sensorimotor deficits at initial follow (p=0.045, p=0.01). In children born ≤ 32 weeks, preeclampsia had higher language production deficits at 3 year follow up (p=0.05).Sensorimotor deficits were greater and sustained in PPROM. Language production deficits were predominant among after 2 years of age in preeclampsia. Racial disparities were found in clinic attendance rates, with Black families most affected.</p><p><strong>Conclusion: </strong>Differences in neurodevelopmental patterns suggest differences in underlying neuronal injuries. Neurologic assessment should occur routinely throughout early childhood to detect delayed deficits after PPROM and preeclampsia and ensure inclusion of underserved or at risk populations.</p>","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40558377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Educating a Child with Down Syndrome in an Inclusive Kindergarten Classroom","authors":"Lema Kabashi, Louise A. Kaczmarek","doi":"10.36648/2472-1786.5.2.81","DOIUrl":"https://doi.org/10.36648/2472-1786.5.2.81","url":null,"abstract":"This case study describes the journey of a kindergartner with Down Syndrome in an inclusive classroom. Characteristics of the participant are discussed in comparison to characteristics of children with Down Syndrome and the impact of those characteristics for the child’s overall development. Various strategies that were effectively used to facilitate the child’s participation, transitioning, academics, and social skills are addressed. The child’s improvements in various areas of development as a result of inclusion in the kindergarten classroom are discussed. Finally, investigating the efficacy of inclusion for children with moderate to severe intellectual disabilities is recommended for further research.","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69708699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conners 3-Parent (Short): Measurement Invariance Across Gender, Concurrent and Discriminant Validities","authors":"R. Gomez, A. Vance","doi":"10.4172/2472-1786.100079","DOIUrl":"https://doi.org/10.4172/2472-1786.100079","url":null,"abstract":"The study examined measurement invariance (configural, factor loadings, thresholds, and error variances), and equivalencies of latent mean scores of the Conners 3-Parent (Short); (C 3-P (S)) across maternal ratings of clinic-referred boys (N = 354) and girls (N = 151), aged 7 to 17 years. It also examined the concurrent and discriminant validities of the scores for the C 3-P (S). Confirmatory factor analysis (CFA) indicated support for the theorized six-factor model. For this model, there was support for full measurement invariance and equivalencies for the latent mean scores. There was also support for the concurrent and discriminant validities of the scores for the C 3-P (S) scales. The findings are discussed in relation to the use of the C 3-P (S).","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2472-1786.100079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70317836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Garza, Arturo Garza Peña, Raúl Calderón, J. Santos-Guzmán, Carlos Aguirre Velázquez
{"title":"Adrenoleukodystrophy linked to Chromosome X with Neuropsychiatric Symptoms and Frontal Involvement: Case Report","authors":"S. Garza, Arturo Garza Peña, Raúl Calderón, J. Santos-Guzmán, Carlos Aguirre Velázquez","doi":"10.4172/2472-1786.100084","DOIUrl":"https://doi.org/10.4172/2472-1786.100084","url":null,"abstract":"Leukodystrophies are a rare group of genetic disorders that affect white matter of the central and peripheral nervous system. We present a clinical case of X-linked adrenoleukodystrophy (X-ALD) in a 9-year old male patient. The patient initially presented with neuropsychiatric symptoms characterized by impulsiveness, hyperactivity, and loss of reading and writing abilities. MRI scan showed a frontal involvement of both cerebral hemispheres. Based on this experience, we recommend that patients with hyperactivity and impulsiveness, and loss of previously acquired abilities such as reading and writing should be thoroughly evaluated to rule out the presence of X-ALD. After making the diagnosis with a complete serum fatty acid profile accompanied by the radiologic findings aforementioned, the patient underwent bone marrow transplant, without a favorable outcome after one year of follow-up.","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70317895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Evolving Parent: Outline of the Evolution of Parenting Styles","authors":"E. Rodriquez","doi":"10.4172/2472-1786.100081","DOIUrl":"https://doi.org/10.4172/2472-1786.100081","url":null,"abstract":"","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2472-1786.100081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70317885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Cardiac Autonomic Control System Response to Submaximal Exercise Test in Children with Cerebral Palsy Compared to Typical Peer","authors":"B. Bhat, Arshad Hussain, W. Qadir, S. Dar","doi":"10.36648/2472-1786.5.2.83","DOIUrl":"https://doi.org/10.36648/2472-1786.5.2.83","url":null,"abstract":"Background: In spite of advances in assessment and management of patients with Autism Spectrum Disorders (ASDs) in west, developing countries including India are lagging far behind in child psychiatry, let alone ASDs. The aims of our study were to find the socio-demographic and clinical profile of children with ASDs in a child psychiatry unit. Methods and Materials: This was a Cross sectional observational descriptive study conducted in Outpatient child psychiatry clinic. Semi-structured questionnaire was used to record the socio-demographic status. The diagnosis of ASDs was made on the basis of Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM IV-TR) after a thorough clinical assessment which was also confirmed by consultant in charge child psychiatry. Intelligence quotient was assessed by clinical psychologist. Descriptive statistical analysis was done and presented as frequencies and percentages. Results: A total of 55 patients were diagnosed with ASDs. Most of the patients were less than 9 years with 52.73% in 4-7 years age group and 21.82% in 7-9 year age group. Males (78.18%) out-numbered females. 52.73% belonged to Nuclear Family and 63.63% were from rural background. 70.91% were staying at home. Autism was the most frequent diagnosis in 61.82% of the patients followed by Pervasive Developmental Disorder not otherwise specified (PDD NOS) in 30.91%. Co-morbid mental retardation (MR) was present in 47(85.45%) of our subjects. Conclusion: 10.4% of children and adolescents with psychiatric disorders were having ASDs with autistic disorder and PDD NOS representing more than 90% of these cases. Despite the growing global attention for inclusive education to these children, only 3% of our cases were receiving inclusive education and about 70% of cases were staying at home.","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69708761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Potential Benefits of PTH Analogs in Prevention of Pathological Fractures in Cerebral Palsy","authors":"Patrisha Shelley, L. Edwards, Rafik Jacob","doi":"10.36648/2472-1786.5.3.86","DOIUrl":"https://doi.org/10.36648/2472-1786.5.3.86","url":null,"abstract":"Osteoporosis is a detrimental disorder of bone that puts patients at increased risk of pathologic fractures. Patients with cerebral palsy (CP), due to a multitude of factors, are at increased risk of developing this disorder. Studies in the past have looked at various treatment options for these patients to reduce and/or prevent pathologic fractures. Most studies have looked into the use of bisphosphonates for prevention. Teriparatide is a recombinant PTH analog that has been shown to increase bone mineral density and reduce fragility fractures in adults with non- CP related osteoporosis. Despite the reduction seen in these studies, empirical evidence for the use of PTH analogs in CP related osteoporosis is scarce. PTH analogs, like Teriparatide, have shown to be beneficial in patients with non-CP related osteoporosis, further studies need to be performed to assess its benefit for patients with CP related osteoporosis.","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69708838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veena Sison, Tracy Stackhouse, Robert Breeze, Terry Hall, Pamela McKenzie, Nicole Tartaglia
{"title":"Arteriovenous Malformation in a Youth with Atypical Autism Symptoms.","authors":"Veena Sison, Tracy Stackhouse, Robert Breeze, Terry Hall, Pamela McKenzie, Nicole Tartaglia","doi":"10.4172/2472-1786.100042","DOIUrl":"https://doi.org/10.4172/2472-1786.100042","url":null,"abstract":"<p><p>Cerebral arteriovenous malformations (AVMs) present a challenge to diagnose in children with developmental disability, because of the overlap in behavioral symptoms and neurologic manifestations. They have been very rarely reported in conjunction with autism spectrum disorder. This case involves a 13 year old male with a history of autism spectrum disorder and significant behavioral issues diagnosed with a thalamic AVM following lateralizing neurologic symptoms. Despite radiosurgical treatment, hemorrhage followed consequently causing extensive neurologic injury and death. This case emphasizes the need for close follow up and coordination within a medical home for children with developmental disabilities. A multidisciplinary team approach is ideal to allow detection of subtle neurologic changes over time that may be masked as behavioral difficulties.</p>","PeriodicalId":92067,"journal":{"name":"Journal of childhood & developmental disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2472-1786.100042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35426571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}