Journal of endocrinology and diabetes mellitus最新文献

Treatment of Diabetic Lower Limb Wounds with Ozonized Sunflower Oil and Collagenase 臭氧化葵花籽油配合胶原酶治疗糖尿病下肢创面

Journal of endocrinology and diabetes mellitus Pub Date : 2020-12-25 DOI: 10.12970/2310-9971.2020.08.03

D. I. Kozusny-Andreani, R. Ramos, R. Zângaro, Luis Viotto, Camila Viotto

引用次数: 1

Lymphocytic Hypophysitis: Case Report 淋巴细胞性骨膜炎1例报告

Journal of endocrinology and diabetes mellitus Pub Date : 2018-10-31 DOI: 10.12970/2310-9971.2018.06.04

N. Haraj, S. Lezar, F. Louda, S. Aziz, A. Chadli

引用次数: 0

Bariatric Surgery and its Place in Modern Diabetology 减肥外科及其在现代糖尿病学中的地位

Journal of endocrinology and diabetes mellitus Pub Date : 2018-10-05 DOI: 10.12970/2310-9971.2018.06.03

D. Cheța, V. Chirilă, N. Paulescu

引用次数: 0

Hypovitaminosis D and Type 2 Diabetes: What Correlation? Control Case Study about 110 Cases 维生素D缺乏症和2型糖尿病:有什么关系?对照病例研究约110例

Journal of endocrinology and diabetes mellitus Pub Date : 2018-08-01 DOI: 10.12970/2310-9971.2018.06.02

S. Bellouk, S. Aziz, A. Chadli

{"title":"Hypovitaminosis D and Type 2 Diabetes: What Correlation? Control Case Study about 110 Cases","authors":"S. Bellouk, S. Aziz, A. Chadli","doi":"10.12970/2310-9971.2018.06.02","DOIUrl":"https://doi.org/10.12970/2310-9971.2018.06.02","url":null,"abstract":"Introduction : Relationship between diabetes and the (OH) vitamin D status raises several controversies; The aim of our study is to evaluate Vitamin D status in Moroccan type 2 diabetic women (DT2) by comparing it with a non-diabetic group (T). Secondary purpose was to establish relationships between Vitamine D status and T2D patients various metabolic, clinical and therapeutic parameters. Materials and Methods : This a cross-sectional case-control study including 110 patients with a Vitamin D dose (60 DT2 / 50 controls> 30 years). We excluded patients with a disease involving phosphocalcic metabolism or receiving Vitamin D supplementation or advanced renal or hepatic failure. Variables studied in the DT2 group were age, diabetes duration, glycemic equilibrium, BMI, degenerative complications, antidiabetic treatment, the menopause and vitamin D. Results were compared to a non-diabetic control group according to age, BMI and menopausal status. Results : Mean age was 51.5 ± 10.95 (DT2) vs 48.9 ± 11.2 years (T). Mean DT2 BMI was 32.1 vs 27.7 Kg / m 2 . Mean diabetes duration was 7.13 years with mean HBA1c at 9.17%. Hypovitaminosis D was present in 85% DT2, these results were comparable to the control group (84%). Mean level of Vitamin D was lower in the DT2 group: 17 ± 10.6 vs 22.2 ± 11.4 ng / ml (p = 0.005). 39% of TD2 were deficient vs 23% (T) p 35kg / m 2 (p= 0.003) with no significant relationship to age or menopausal status. In the DT2 group, there was a negative correlation between serum vitamin D levels and diabetes duration and BMI. Without relationship with HbA1c, degenerative complications or antidiabetic treatment. Conclusion : Hypovitaminosis D is as frequent in the diabetic population as in non-diabetic patients with lower rates and high prevalence in obese patients with ancient diabetes.","PeriodicalId":91903,"journal":{"name":"Journal of endocrinology and diabetes mellitus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45256503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute and Chronic Kudzu Improves Plasma Glucose Tolerance in Non-Diabetic CD-1 Mice. 急性和慢性葛根改善非糖尿病 CD-1 小鼠的血浆葡萄糖耐受性

Journal of endocrinology and diabetes mellitus Pub Date : 2014-01-01 DOI: 10.12970/2310-9971.2014.02.02.6

Scott Carlson, Jeevan K Prasain, Ning Peng, Yanying Dai, J Michael Wyss

{"title":"Acute and Chronic Kudzu Improves Plasma Glucose Tolerance in Non-Diabetic CD-1 Mice.","authors":"Scott Carlson, Jeevan K Prasain, Ning Peng, Yanying Dai, J Michael Wyss","doi":"10.12970/2310-9971.2014.02.02.6","DOIUrl":"10.12970/2310-9971.2014.02.02.6","url":null,"abstract":"<p><p>Previous studies demonstrate that kudzu root extract and its major isoflavone (puerarin) improve glucose metabolism in animal models of insulin resistance and type 2 diabetes; however, these beneficial effects have not been investigated in normal glycemic mice. The present study investigates the effect of acute and chronic kudzu root extract supplementation on glucose tolerance in normoglycemic CD-1 mice. Male, adult CD-1 mice were fed a phytoestrogen-free diet containing 0.2% or 0.0% kudzu root extract for 6 weeks. Thereafter, they were acutely administered kudzu root extract (75 mg/kg BW; oral) or vehicle followed by a glucose challenge (2 g/kg BW; oral). In control fed mice, the acute glucose challenge increased blood glucose ~300% after 30 minutes, and acute kudzu root extract administration significantly blunted this response by ~50%. In mice chronically fed a kudzu-supplemented diet, glucose tolerance was improved, and acute treatment caused no additional improvement. Irrespective of treatment, all mice were normoglycemic at the start of each glucose challenge. Administration of insulin resulted in a larger decrease in blood glucose in chronic kudzu-supplemented compared to control mice. Co-administration of phloridzin (a specific inhibitor of SGLT-mediated glucose uptake), improved glucose tolerance in acutely kudzu-treated mice but had no significant effect on glucose tolerance in chronically treated mice. These results indicate that both acute and chronic administration of kudzu root extract improves glucose tolerance in a normal glycemic mouse strain and that the effects of chronic kudzu feeding may be mediated, in part, by enhanced insulin sensitivity (chronic) and inhibition of sodium dependent glucose transport.</p>","PeriodicalId":91903,"journal":{"name":"Journal of endocrinology and diabetes mellitus","volume":"2 ","pages":"70-77"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2f/08/nihms814315.PMC5330362.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34779350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0