{"title":"Dependence of Cognitive and Mental Development in Children with Autism Spectrum Disorder on Thyroid Dysfunction and Cortisol Imbalance","authors":"A. Maximova","doi":"10.24966/he-9640/100017","DOIUrl":"https://doi.org/10.24966/he-9640/100017","url":null,"abstract":"Causal relationships and statistically proven correlations have been established between hypothyroidism and / or cortisol imbalance and negative behaviors and violations of mental and cognitive development in children with autism spectrum disorder. Also, correcting hormonal disorders led to a decrease in negative behaviors and noticeable improvements in mental states and cognitive functions. Successful therapeutic strategies are proposed for all types of hormonal disorders considered.","PeriodicalId":91874,"journal":{"name":"HSOA journal of human endocrinology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88465569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case Report of Adrenal Lymphangioma","authors":"Ponce de León-Ballesteros Guillermo","doi":"10.24966/he-9640/100013","DOIUrl":"https://doi.org/10.24966/he-9640/100013","url":null,"abstract":"","PeriodicalId":91874,"journal":{"name":"HSOA journal of human endocrinology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76509787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Graves' Disease in Men's Subjects","authors":"D. Diédhiou","doi":"10.24966/HE-9640/100012","DOIUrl":"https://doi.org/10.24966/HE-9640/100012","url":null,"abstract":"particularities in women are sufficiently well documented [3], specific data in male subjects remain rare, most often embedded in an overall description of Graves’ disease. A moroccan series reports on 6 years of follow-up, a mean age of 45 years, a more severe Graves’ orbitopathy and a higher relapse rate compared to the female sex [6]. The objective of this work was to study the epidemiological, clinical and evolutionary characteristics of Graves’ disease in male subjects at the Medical Clinic II of Abass Ndao University Hospital Center in Dakar (Senegal). Abstract Graves’ disease remains the most frequent cause of hyperthy- roidism but poorly described in men. The objective was to study the specificities of Graves’ disease in this population at Abass Ndao Uni versity Hospital Center in Dakar (Senegal). It was a descriptive and analytical retrospective study conducted over 20 years. The agnosis, a larger goiter, a high rate of lost sight and relapse. The follow-up needs to take into account the risk factors of failure to im- prove the choices and therapeutic recourses. Radioiodine treatment remains a necessity.","PeriodicalId":91874,"journal":{"name":"HSOA journal of human endocrinology","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74023906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasma Citrate Homeostasis: How It Is Regulated; And Its Physiological and Clinical Implications. An Important, But Neglected, Relationship in Medicine.","authors":"L. Costello, R. Franklin","doi":"10.24966/HE-9640/100005","DOIUrl":"https://doi.org/10.24966/HE-9640/100005","url":null,"abstract":"The homeostatic maintenance of a normal plasma citrate concentration is an important factor in humans and in animals; and is required for many normal physiological activities. Dysregulation of normal plasma citrate presents pathophysiological hypocitricemic or hypercitricemic conditions. This can lead to clinical consequences in many areas of medicine; such as impaired blood clotting, altered acid/base status, impaired neuromuscular/cardiac activities, hypocitraturia and stone formation, bone disorders with loss of bone strength and increased fractures, hypocitricemia of surgical stress. These important implications of citrate relationships have been largely ignored by the contemporary clinical and biomedical community; to the extent that it is not even described in most current textbooks and review papers. This review describes the physiological, endocrine, and metabolic relationships in the normal regulation and maintenance of plasma citrate; and presents some important clinical consequences of its dysfunctional maintenance. The importance of bone, kidney and liver activities in the maintenance of normal plasma citrate is described along with the citricemic roles of parathyroid hormone, calcitonin and vitamin D. These factors and relationships are presented as the contemporary understanding of the integrated regulation of plasma citrate as the basis for its clinical importance in medicine. The exclusion of these citrate relationships leads to misunderstanding and misrepresentation of physiological and clinical conditions in many issues in medicine and paramedicine areas. The intent of this review is to revive the interest and support for research to address the many unknown and speculative issues of plasma citrate regulation and its important clinical implications. This is in the best interest of the medical community and the public-at-large.","PeriodicalId":91874,"journal":{"name":"HSOA journal of human endocrinology","volume":"151 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74749640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasma Citrate Homeostasis: How It Is Regulated; And Its Physiological and Clinical Implications. An Important, But Neglected, Relationship in Medicine.","authors":"Leslie C Costello, Renty B Franklin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The homeostatic maintenance of a normal plasma citrate concentration is an important factor in humans and in animals; and is required for many normal physiological activities. Dysregulation of normal plasma citrate presents pathophysiological hypocitricemic or hypercitricemic conditions. This can lead to clinical consequences in many areas of medicine; such as impaired blood clotting, altered acid/base status, impaired neuromuscular/cardiac activities, hypocitraturia and stone formation, bone disorders with loss of bone strength and increased fractures, hypocitricemia of surgical stress. These important implications of citrate relationships have been largely ignored by the contemporary clinical and biomedical community; to the extent that it is not even described in most current textbooks and review papers. This review describes the physiological, endocrine, and metabolic relationships in the normal regulation and maintenance of plasma citrate; and presents some important clinical consequences of its dysfunctional maintenance. The importance of bone, kidney and liver activities in the maintenance of normal plasma citrate is described along with the citricemic roles of parathyroid hormone, calcitonin and vitamin D. These factors and relationships are presented as the contemporary understanding of the integrated regulation of plasma citrate as the basis for its clinical importance in medicine. The exclusion of these citrate relationships leads to misunderstanding and misrepresentation of physiological and clinical conditions in many issues in medicine and paramedicine areas. The intent of this review is to revive the interest and support for research to address the many unknown and speculative issues of plasma citrate regulation and its important clinical implications. This is in the best interest of the medical community and the public-at-large.</p>","PeriodicalId":91874,"journal":{"name":"HSOA journal of human endocrinology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345696/pdf/nihms841759.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34806505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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