发布求助
文献互助 智能选刊 最新文献

Computational biology journal最新文献

筛选
英文 中文
TransPS: A Transcriptome Post Scaffolding Method for Assembling High Quality Contigs. TransPS:一种用于组装高质量基因组的转录组后支架方法。
Computational biology journal Pub Date : 2014-01-01 Epub Date: 2014-05-28 DOI: 10.1155/2014/961823
Mingming Liu, Zach N Adelman, Liqing Zhang
{"title":"TransPS: A Transcriptome Post Scaffolding Method for Assembling High Quality Contigs.","authors":"Mingming Liu,&nbsp;Zach N Adelman,&nbsp;Liqing Zhang","doi":"10.1155/2014/961823","DOIUrl":"https://doi.org/10.1155/2014/961823","url":null,"abstract":"<p><strong>Motivation: </strong>As the development of the high throughput sequencing technologies, transcriptome can be sequenced with a low price and high efficiency. Sequence assembly approaches have been renewed to meet the new requirements from new sequencing technologies. Assembly strategies are important for biologists who need to assemble the transcriptome generated in their experiments. However, some modern de novo assembly strategies generate a large section of redundant contigs due to sequence variations, which greatly affect downstream analysis and experiments. This work proposed TransPS, a post transcriptome scaffolding method to generate high quality transcriptomes.</p><p><strong>Results: </strong>TransPS shows promising results on the test transcriptome data sets where the redundancy is greatly reduced by at least 50%, while the coverage is improved considerately.</p><p><strong>Availability: </strong>The web server and source code are available at https://bioinformatics.cs.vt.edu/zhanglab/transps/.</p>","PeriodicalId":91855,"journal":{"name":"Computational biology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/961823","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34784776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信