Archives of emergency medicine and critical care最新文献

筛选

英文中文

Curvularia and the Brain: Case Demonstration of Optimal Management. 曲霉与大脑:最佳管理的案例论证。

Archives of emergency medicine and critical care Pub Date : 2023-02-01 DOI: 10.1055/s-0043-1762343

M. Goldman, Ramya Reddy, B. Lucke-Wold, A. Barpujari, Miles E. Cameron, Ken Porche, D. Laurent, E. Duarte, Brian C. Lobo, M. Koch

{"title":"Curvularia and the Brain: Case Demonstration of Optimal Management.","authors":"M. Goldman, Ramya Reddy, B. Lucke-Wold, A. Barpujari, Miles E. Cameron, Ken Porche, D. Laurent, E. Duarte, Brian C. Lobo, M. Koch","doi":"10.1055/s-0043-1762343","DOIUrl":"https://doi.org/10.1055/s-0043-1762343","url":null,"abstract":"Background\u0000Curvularia is a ubiquitous fungus found in tropical climates and has been reported to grow on marijuana leaves. Rarely, it can infect humans and propagate from the nasal sinuses into the brain.\u0000\u0000\u0000Case\u0000A 28-year-old immunocompetent patient presented with history of nasal polyps, headache, and subtle visual deficits on the right. Imaging revealed what appeared to be an invasive mass growing through the ethmoid and sphenoid sinuses into the anterior cranial fossa.\u0000\u0000\u0000Results\u0000Otolaryngology performed an endoscopic nasal biopsy with pathology and cultures consistent for Curvularia (figure 6). A combination case with neurosurgery and otolaryngology was planned. Surgeons used a bifrontal craniotomy and endonasal approach for gross total resection. Following resection, the patient was placed on 4 weeks of amphotericin treatment followed by 12 months of voriconazole based on recommendations by infectious disease. The patient has been stable since surgery.\u0000\u0000\u0000Conclusion\u0000Curvularia is a rare but potentially life threatening central nervous system infection that can be acquired from inhalational marijuana use. This illustrative case shows the importance of aggressive debridement followed by broad spectrum antifungal treatment to optimize outcome. With marijuana's increasing popularity, Curvalaria should be included on the differential diagnosis.","PeriodicalId":91657,"journal":{"name":"Archives of emergency medicine and critical care","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91514454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurologic Injury and Dementia: Update on Current Physiotherapeutic Intervention. 神经损伤和痴呆症：当前物理治疗干预的最新进展。

Archives of emergency medicine and critical care Pub Date : 2022-01-01 Epub Date: 2022-05-08

Kevin Pierre, Alec Clark, Patrick Felisma, Sydney Weisman, Brandon Lucke-Wold

引用次数: 0

Curvularia and the Brain: Case Demonstration of Optimal Management. 卷曲病与大脑最佳管理案例展示。

Archives of emergency medicine and critical care Pub Date : 2022-01-01 Epub Date: 2022-08-18

Matthew Goldman, Ramya Reddy, Brandon Lucke-Wold, Arnav Barpujari, Miles Cameron, Ken Porche, Dimitri Laurent, Ernesto Duarte, Brian C Lobo, Matthew Koch

{"title":"Curvularia and the Brain: Case Demonstration of Optimal Management.","authors":"Matthew Goldman, Ramya Reddy, Brandon Lucke-Wold, Arnav Barpujari, Miles Cameron, Ken Porche, Dimitri Laurent, Ernesto Duarte, Brian C Lobo, Matthew Koch","doi":"","DOIUrl":"","url":null,"abstract":"Background: Curvularia is a ubiquitous fungus found in tropical climates and has been reported to grow on marijuana leaves. Rarely, it can infect humans and propagate from the nasal sinuses into the brain.Case: A 28-year-old immunocompetent patient presented with history of nasal polyps, headache, and subtle visual deficits on the right. Imaging revealed what appeared to be an invasive mass growing through the ethmoid and sphenoid sinuses into the anterior cranial fossa.Results: Otolaryngology performed an endoscopic nasal biopsy with pathology and cultures consistent for Curvularia (figure 6). A combination case with neurosurgery and otolaryngology was planned. Surgeons used a bifrontal craniotomy and endonasal approach for gross total resection. Following resection, the patient was placed on 4 weeks of amphotericin treatment followed by 12 months of voriconazole based on recommendations by infectious disease. The patient has been stable since surgery.Conclusion: Curvularia is a rare but potentially life threatening central nervous system infection that can be acquired from inhalational marijuana use. This illustrative case shows the importance of aggressive debridement followed by broad spectrum antifungal treatment to optimize outcome. With marijuana's increasing popularity, Curvalaria should be included on the differential diagnosis.","PeriodicalId":91657,"journal":{"name":"Archives of emergency medicine and critical care","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35346189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0