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Journal of enzymology and metabolism最新文献

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Alterations of Cholesterol Metabolism in Inflammation-Induced Atherogenesis. 炎症诱导的动脉粥样硬化中胆固醇代谢的改变。
Journal of enzymology and metabolism Pub Date : 2016-01-01 Epub Date: 2016-05-31
David P Hajjar, Katherine A Hajjar
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引用次数: 0
Kupffer Cell Metabolism and Function. 库普弗细胞的新陈代谢和功能
Journal of enzymology and metabolism Pub Date : 2015-01-01 Epub Date: 2015-08-14
Anh Thu Nguyen-Lefebvre, Anatolij Horuzsko
{"title":"Kupffer Cell Metabolism and Function.","authors":"Anh Thu Nguyen-Lefebvre, Anatolij Horuzsko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Kupffer cells are resident liver macrophages and play a critical role in maintaining liver functions. Under physiological conditions, they are the first innate immune cells and protect the liver from bacterial infections. Under pathological conditions, they are activated by different components and can differentiate into M1-like (classical) or M2-like (alternative) macrophages. The metabolism of classical or alternative activated Kupffer cells will determine their functions in liver damage. Special functions and metabolism of Kupffer cells suggest that they are an attractive target for therapy of liver inflammation and related diseases, including cancer and infectious diseases. Here we review the different types of Kupffer cells and their metabolism and functions in physiological and pathological conditions.</p>","PeriodicalId":91312,"journal":{"name":"Journal of enzymology and metabolism","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141094790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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