IASTED International Conference on Computational and Systems Biology : November 13-14, 2006, Dallas, Texas, USA (CASB 2006)最新文献

筛选
英文 中文
A NEW CLUSTERING METHOD AND ITS APPLICATION TO PROTEOMIC PROFILING FOR COLON CANCER. 一种新的聚类方法及其在结肠癌蛋白质组学分析中的应用。
Yongbin Ou, Lan Guo, Cun-Quan Zhang
{"title":"A NEW CLUSTERING METHOD AND ITS APPLICATION TO PROTEOMIC PROFILING FOR COLON CANCER.","authors":"Yongbin Ou,&nbsp;Lan Guo,&nbsp;Cun-Quan Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this paper, we introduce a new clustering method: quasi-clique merger, and its associated data pretreatment programs. This program constructs non-binary hierarchical trees with much smaller number of clusters in the outputs. And overlapping clusters are also allowed in the outputs. We applied this new method to cluster 60 human cancer cell lines (the NCI-60) using the previously identified proteomic determinants for chemosensitivity of 5-Fluorouracil (5-FU). All colon cancer cell lines were aggregated into a single cluster, indicating that the eight proteomic markers are potential diagnostic markers of colon cancer. The results based on the new clustering method have surpassed those based on previous methods on the same datasets.</p>","PeriodicalId":90846,"journal":{"name":"IASTED International Conference on Computational and Systems Biology : November 13-14, 2006, Dallas, Texas, USA (CASB 2006)","volume":"2006 ","pages":"68-72"},"PeriodicalIF":0.0,"publicationDate":"2006-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445888/pdf/nihms686085.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33350150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信