ISRN PhysiologyPub Date : 2014-02-23DOI: 10.1155/2014/676235
Vernon Bond, Bryan H Curry, R George Adams, M Sadegh Asadi, Kimani A Stancil, Richard M Millis, Georges E Haddad
{"title":"Effects of Nitrate Supplementation on Cardiovascular and Autonomic Reactivity in African-American Females.","authors":"Vernon Bond, Bryan H Curry, R George Adams, M Sadegh Asadi, Kimani A Stancil, Richard M Millis, Georges E Haddad","doi":"10.1155/2014/676235","DOIUrl":"https://doi.org/10.1155/2014/676235","url":null,"abstract":"<p><p>Previous studies have shown that beetroot juice (BJ) decreases systolic blood pressure (SBP) and oxygen demand. This study tests the hypothesis that a beetroot juice (BJ) treatment increases heart rate variability (HRV) measured by the average standard deviation of normal-normal electrocardiogram RR intervals (SDNN) and the low frequency (LF), mainly sympathetic, fast Fourier transform spectral index of HRV. The subjects were 13 healthy young adult African-American females. Placebo control orange juice (OJ) and BJ treatments were given on separate days. Blood nitric oxide [NO], SBP and RR intervals were measured at rest and at constant workloads set to 40% and 80% of the predetermined VO<sub>2peak</sub>. Two hours after ingestion the BJ treatment increased [NO] and decreased SBP. BJ also increased SDNN at rest and at the 40% VO<sub>2peak</sub> workload, without significant effects on LF. SDNN was significantly greater after the BJ than after the OJ treatment, across the two physical activity conditions and SDNN was (negatively) correlated with SBP. These results suggest that BJ decreases SBP and increases HRV at rest and during aerobic exercise. Similar results in subjects with prehypertension or hypertension could translate to a dietary nitrate treatment for hypertension.</p>","PeriodicalId":89957,"journal":{"name":"ISRN Physiology","volume":"2014 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/676235","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32817477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN PhysiologyPub Date : 2013-01-01DOI: 10.1155/2013/619319
Rebecca M C Spencer
{"title":"Neurophysiological Basis of Sleep's Function on Memory and Cognition.","authors":"Rebecca M C Spencer","doi":"10.1155/2013/619319","DOIUrl":"10.1155/2013/619319","url":null,"abstract":"<p><p>A wealth of recent studies support a function of sleep on memory and cognitive processing. At a physiological level, sleep supports memory in a number of ways including neural replay and enhanced plasticity in the context of reduced ongoing input. This paper presents behavioral evidence for sleep's role in selective remembering and forgetting of declarative memories, in generalization of these memories, and in motor skill consolidation. Recent physiological data reviewed suggests how these behavioral changes might be supported by sleep. Importantly, in reviewing these findings, an integrated view of how distinct sleep stages uniquely contribute to memory processing emerges. This model will be useful in developing future behavioral and physiological studies to test predictions that emerge.</p>","PeriodicalId":89957,"journal":{"name":"ISRN Physiology","volume":" ","pages":"619319"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40285347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ISRN PhysiologyPub Date : 2013-01-01DOI: 10.1155/2013/756276
Richard M Millis, Vernon Bond, M Sadegh Asadi, Georges E Haddad, Richard G Adams
{"title":"Oxygen Consumption at 30 W of Exercise Is Surrogate for Peak Oxygen Consumption in Evaluation of Cardiorespiratory Fitness in Young-Adult African-American Females.","authors":"Richard M Millis, Vernon Bond, M Sadegh Asadi, Georges E Haddad, Richard G Adams","doi":"10.1155/2013/756276","DOIUrl":"https://doi.org/10.1155/2013/756276","url":null,"abstract":"<p><p>Body mass index (BMI) is negatively correlated with cardiorespiratory fitness, measured by maximal or peak oxygen consumption (VO<sub>2peak</sub>). VO<sub>2peak</sub> measurements require heavy aerobic exercise to near exhaustion which increases the potential for adverse cardiovascular events. This study tests the hypothesis that VO<sub>2</sub> measured at a fixed submaximal workload of 30 W is a surrogate for VO<sub>2peak</sub>. We studied 42 normotensive African-American female university students, 18-25 years of age. We measured VO<sub>2peak</sub>, blood pressure, and VO<sub>2</sub> at a 30 W exercise workload and computed BMI. We found significant negative correlations between BMI and VO<sub>2peak</sub> (<i>r</i> = -0.41, <i>P</i> < 0.01) and between BMI and VO<sub>2</sub> at 30 W (<i>r</i> = -0.53, <i>P</i> < 0.001). Compared to VO<sub>2peak</sub>, VO<sub>2</sub> at 30 W increased the significance of the negative correlation with BMI. The heart rate-systolic pressure product at 30 W was positively correlated with BMI (<i>r</i> = 0.36, <i>P</i> < 0.01) and negatively correlated with VO<sub>2peak</sub> (<i>r</i> = -0.38, <i>P</i> < 0.001). The positive correlation between BMI and the heart rate-systolic pressure product and the greater negative correlation between VO<sub>2</sub> and BMI at 30 W of exercise than that at exercise to fatigue suggest that normalized measurements of VO<sub>2</sub> at the fixed exercise workload of 30 W could be useful surrogates for measurements of VO<sub>2peak</sub>.</p>","PeriodicalId":89957,"journal":{"name":"ISRN Physiology","volume":"2013 ","pages":"756276"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/756276","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32083862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}