International journal of molecular medical science最新文献

Automated analysis method and device for PDS catalyst in HPF process HPF工艺中PDS催化剂的自动化分析方法及装置

International journal of molecular medical science Pub Date : 2025-04-01 DOI: 10.3724/jmolsci.2025060002

Jiaxin Wang, Jinlan YANG, Mengyuan Huang, Liang Zhao, Baoli Li, Yang Li

{"title":"Automated analysis method and device for PDS catalyst in HPF process","authors":"Jiaxin Wang, Jinlan YANG, Mengyuan Huang, Liang Zhao, Baoli Li, Yang Li","doi":"10.3724/jmolsci.2025060002","DOIUrl":"https://doi.org/10.3724/jmolsci.2025060002","url":null,"abstract":"Desulfurization of coke oven gas (COG) is a critical step for achieving green and sustainable development in the coking industry. Ammonium binuclear cobalt phthalocyanine sulfonate (PDS), serving as the core catalyst in the Hydroquinone-PDS-Ferrous sulfate (HPF) desulfurization process, requires precise concentration monitoring for process optimization. To address the limitations of traditional detection methods, including insufficient sensitivity, cumbersome manual operations, and weak anti-interference capability, this study developed a fully automated analytical system and method based on spectrophotometry, thereby filling a technological gap in automated PDS detection. Systematic performance validation demonstrated that the autoanalyzer exhibits excellent sensitivity and a wide linear range, with results consistent with industrial standard methods. Leveraging a programmable logic controller (PLC), the system achieves end-to-end automation from sample pretreatment to data feedback, overcoming limitations inherent in manual operations such as delayed sample processing and human-induced errors, which significantly enhances the sensitivity and timeliness of PDS concentration monitoring in complex industrial matrices. The proposed method offers triple benefits of environmental friendliness, cost-effectiveness, and social value, providing key technical support for the coking industry.","PeriodicalId":89943,"journal":{"name":"International journal of molecular medical science","volume":"41 2","pages":"25020508-25020508"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciengine.com/doi/pdf/E3B79307EDEE4C78828A38E17783C23F","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147895859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural optimization of carbonized polymer dots for modulation of electrochemical performance of aqueous electrolytes 碳化聚合物点对水电解质电化学性能调制的结构优化

International journal of molecular medical science Pub Date : 2025-04-01 DOI: 10.3724/jmolsci.2025050003

Xinyao HUANG, Jiahui Wang, Guo‐Duo Yang, Xin Ji, Haizhu Sun

{"title":"Structural optimization of carbonized polymer dots for modulation of electrochemical performance of aqueous electrolytes","authors":"Xinyao HUANG, Jiahui Wang, Guo‐Duo Yang, Xin Ji, Haizhu Sun","doi":"10.3724/jmolsci.2025050003","DOIUrl":"https://doi.org/10.3724/jmolsci.2025050003","url":null,"abstract":"Aqueous zinc ion batteries (AZIBs) are considered to be one of the most promising energy storage devices due to the advantages of high cost-effectiveness, safety, and environmental friendliness. However, they suffer from problems such as Zn dendrites growth and by-product generation. Carbonized polymer dots (CPDs) with polar groups as additive have been introduced to modulate the solvated structure of Zn2+ and reduce the water activity, promoting the uniform deposition of Zn and inhibiting the occurrence of side reactions. However, CPDs with different functional group contents from different precursor molar ratios variably affect the electrochemical performance of aqueous electrolytes. Therefore, in this work, we designed and synthesized CPDs with different molar ratios of the precursors (citric acid and urea) as electrolyte additives for AZIBs and explore the optimal molar ratios of the precursors. The Zn//Zn symmetrical cells using electrolytes with the optimal ratios CPDs achieve an extended cycle life over 615 h at 2 mA∙cm−2 and 1 mAh∙cm−2. This work offers great potential for future practical applications of CPDs.","PeriodicalId":89943,"journal":{"name":"International journal of molecular medical science","volume":"41 2","pages":"25020207-25020207"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciengine.com/doi/pdf/7E06A0EB9F654A7389A60C4B05221BE1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyoxometalate-based anti-freezing hydrogels with high proton conductivity 具有高质子导电性的多金属氧酸盐基抗冻水凝胶

International journal of molecular medical science Pub Date : 2025-02-01 DOI: 10.3724/jmolsci.2024110002

Shuping Xue, Jingqi Yang, Jun Geng, Maochun ZHU, Ying Lü, Shuxia Liu

{"title":"Polyoxometalate-based anti-freezing hydrogels with high proton conductivity","authors":"Shuping Xue, Jingqi Yang, Jun Geng, Maochun ZHU, Ying Lü, Shuxia Liu","doi":"10.3724/jmolsci.2024110002","DOIUrl":"https://doi.org/10.3724/jmolsci.2024110002","url":null,"abstract":"With several favorable properties, including flexibility, biocompatibility, and conductivity, conductive hydrogels are one of the most promising flexible sensing materials and are expected to be used in areas such as wearable devices, health monitoring, and electronic skin. However, water in hydrogels freezes at sub-zero temperatures, which greatly affects the performance of hydrogels at low temperatures. Therefore, it remains a challenge to prepare conductive hydrogels that can maintain their performance at low temperatures. In this work, we developed a series of polyoxometalate-based anti-freezing hydrogels with high conductivity by constructing a semi-interpenetrating network using polyacrylamide and sodium alginate, and then introducing H3PW12O40 (HPW) and glycerol into it via a facile soaking strategy. Among the obtained anti-freezing hydrogels, PSWG-50% hydrogel has the proton conductivity of 0.325 <?A3B2 pi129?>S·cm −1 at room temperature and can maintain high proton conductivity over a wide temperature range from −20 <?A3B2 pi129?>to <sc>65 °C</sc>. Based on these advantages, PSWG-50% hydrogel has been used in flexible sensors to monitor human movement, such as limb bending. Whether in mild or cold environments, PSWG-50% hydrogel shows great potential in the field of flexible sensor.","PeriodicalId":89943,"journal":{"name":"International journal of molecular medical science","volume":"41 1","pages":"25010207-25010207"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciengine.com/doi/pdfView/9E1678E7DBD4431BA0149A002F3E3375","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147893951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Saturated Unsaturated Fatty Acids on Macrophage Inflammatory Status 饱和不饱和脂肪酸对巨噬细胞炎症状态的影响

International journal of molecular medical science Pub Date : 2023-01-01 DOI: 10.5376/ijmms.2023.13.0001

Yaming Zhao, Linfei Jin, Zhan Yang, Yin Yajun, Zhang Jin

引用次数: 0

A Brief Analysis of the Principles and Application Prospects of Different Gene Editing Technologies 浅析不同基因编辑技术的原理及应用前景

International journal of molecular medical science Pub Date : 2023-01-01 DOI: 10.5376/ijmms.2023.13.0003

Wei Wang

引用次数: 0

Theoretical and Historical Development of Gene Editing and Gene Therapy 基因编辑与基因治疗的理论与历史发展

International journal of molecular medical science Pub Date : 2023-01-01 DOI: 10.5376//ijmms.2023.13.0002

Wei Wang

引用次数: 0

Relationship Between SARS-CoV-2 Transmission and Season and Climate SARS-CoV-2传播与季节和气候的关系

International journal of molecular medical science Pub Date : 2022-01-01 DOI: 10.5376/ijmms.2022.12.0001

Hong Gao, Jiayao Zhou, J Zhang

引用次数: 0

Absence of Genomic Ikaros/IKZF1 Deletions in Pediatric B-Precursor Acute Lymphoblastic Leukemia. 儿童b前体急性淋巴细胞白血病中基因组Ikaros/IKZF1缺失的缺失

International journal of molecular medical science Pub Date : 2013-07-29 DOI: 10.5376/ijmms.2013.03.0009

Sanjive Qazi, Hong Ma, Fatih M Uckun

{"title":"Absence of Genomic Ikaros/IKZF1 Deletions in Pediatric B-Precursor Acute Lymphoblastic Leukemia.","authors":"Sanjive Qazi, Hong Ma, Fatih M Uckun","doi":"10.5376/ijmms.2013.03.0009","DOIUrl":"https://doi.org/10.5376/ijmms.2013.03.0009","url":null,"abstract":"Here we report the results of gene expression analyses using multiple probesets aimed at determining the incidence of Ikaros/IKZF1 deletions in pediatric B-precursor acute lymphoblastic leukemia (BPL). Primary leukemia cells from 122 Philadelphia chromosome (Ph)+ BPL patients and 237 Ph- BPL patients as well as normal hematopoietic cells from 74 normal non-leukemic bone marrow specimens were organized according to expression levels of IKZF1 transcripts utilizing two-way hierarchical clustering technique to identify specimens with low IKZF1 expression for the 10 probesets interrogating Exons 1 through 4 and Exon 8. Our analysis demonstrated no changes in expression that would be expected from homozygous or heterozygous deletions of IKZF1 in primary leukemic cells. Similar results were obtained in gene expression analysis of primary leukemic cells from 20 Ph+ positive and 155 Ph- BPL patients in a validation dataset. Taken together, our gene expression analyses in 534 pediatric BPL cases, including 142 cases with Ph+ BPL, contradict previous reports that were based on SNP array data and suggested that Ph+ pediatric BPL is characterized by a high frequency of homozygous or heterozygous IKZF1 deletions. Further, exon-specific genomic PCR analysis of primary leukemia cells from 21 high-risk pediatric BPL patients and 11 standard-risk pediatric BPL patients, and 8 patients with infant BPL did not show any evidence for homozygous IKZF1 locus deletions. Nor was there any evidence for homozygous or heterozygous intragenic IKZF1 deletions.","PeriodicalId":89943,"journal":{"name":"International journal of molecular medical science","volume":"3 9","pages":"72-82"},"PeriodicalIF":0.0,"publicationDate":"2013-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902699/pdf/nihms-517923.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32074140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

KU HAPLOINSUFFIENCY CAUSES A LYMPHOPROLIFERATIVE DISORDER OF IMMATURE T-CELL PRECURSORS DUE TO IKAROS MALFUNCTION. 由于 ikaros 功能失常，ku 单倍性会导致未成熟 t 细胞前体淋巴组织增生性疾病。

International journal of molecular medical science Pub Date : 2013-06-21 DOI: 10.5376/ijmms.2013.03.0007

Zahide Ozer, Sanjive Qazi, Rita Ishkhanian, Paul Hasty, Hong Ma, Fatih M Uckun

{"title":"KU HAPLOINSUFFIENCY CAUSES A LYMPHOPROLIFERATIVE DISORDER OF IMMATURE T-CELL PRECURSORS DUE TO IKAROS MALFUNCTION.","authors":"Zahide Ozer, Sanjive Qazi, Rita Ishkhanian, Paul Hasty, Hong Ma, Fatih M Uckun","doi":"10.5376/ijmms.2013.03.0007","DOIUrl":"10.5376/ijmms.2013.03.0007","url":null,"abstract":"Ikaros (IK) malfunction has been implicated in the pathogenesis of acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Therefore, a stringent regulation of IK activity is very important. Here we provide unique genetic and biochemical evidence that the Ku protein components Ku70 and Ku80 act as positive regulators of IK function via formation of IK-Ku70 and IK-Ku80 heterodimers with augmented sequence-specific DNA binding activity. siRNA-mediated depletion of Ku70 or Ku80 reduced the sequence-specific DNA binding activity of IK in EMSA as well as the RT-PCR measured IK target gene expression levels in human cells. The interaction of Ku components with IK likely contributes to the anti-leukemic effects of IK as a tumor suppressor, because Ku70 as well as Ku80 haploinsuffiency in mice caused development of a lymphoproliferative disorder (LPD) involving CD2+CD4+CD8+CD1+IL7R+ thymic T-cell precursors with functional IK deficiency.","PeriodicalId":89943,"journal":{"name":"International journal of molecular medical science","volume":"3 7","pages":"50-64"},"PeriodicalIF":0.0,"publicationDate":"2013-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902664/pdf/nihms500314.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32074139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0