Clinical medicine reviews in vascular health最新文献

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Long-Term Effects of Childhood Risk Factors on Cardiovascular Health During Adulthood. 儿童期危险因素对成年期心血管健康的长期影响
Clinical medicine reviews in vascular health Pub Date : 2015-08-12 DOI: 10.4137/CMRVH.S29964
Roman Shrestha, Michael Copenhaver
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引用次数: 48
High-Risk Patients with Hypertension: Clinical Management Options. 高血压高危患者:临床管理选择。
Clinical medicine reviews in vascular health Pub Date : 2013-10-08 DOI: 10.4137/CMRVH.S8109
Candace D McNaughton, Wesley H Self, Phillip D Levy, Tyler W Barrett
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引用次数: 5
LOWERING THE RISK FOR THROMBUS AND STROKE IN ATRIAL FIBRILLATION PATIENTS: Will Dabigatran Replace Warfarin? 降低心房颤动患者血栓形成和中风的风险:达比加群能否取代华法林?
Clinical medicine reviews in vascular health Pub Date : 2013-06-20 DOI: 10.4137/CMRVH.S6415
Alex Y Tan, Michael A Rosenberg
{"title":"LOWERING THE RISK FOR THROMBUS AND STROKE IN ATRIAL FIBRILLATION PATIENTS: Will Dabigatran Replace Warfarin?","authors":"Alex Y Tan, Michael A Rosenberg","doi":"10.4137/CMRVH.S6415","DOIUrl":"10.4137/CMRVH.S6415","url":null,"abstract":"<p><p>The use of oral anticoagulation to reduce stroke risk from thromboembolism has become the cornerstone of management of atrial fibrillation. Dabigatran is a direct thrombin inhibitor, which in contrast to warfarin, does not require regular blood draws for monitoring effect. Randomized controlled studies suggest that dabigatran may be more effective than warfarin at higher doses without an increased bleeding risk, and equally effective at lower doses, with lower bleeding risk. With these apparent advantages comes a higher cost, and limited use in patients with underlying renal or liver disease. In addition, the inability to measure anticoagulant effect, as with warfarin, presents a double-edged sword for clinical use of dabigatran. In this review, we discuss the mechanisms of action, clinical effect, and place in therapy of dabigatran as a possible replacement for warfarin.</p>","PeriodicalId":89751,"journal":{"name":"Clinical medicine reviews in vascular health","volume":"5 ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2013-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170944/pdf/nihms-489714.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32694993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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