Recent patents on regenerative medicine最新文献

Recent Patents Pertaining to Immune Modulation and Musculoskeletal Regeneration with Wharton's Jelly Cells. 最近的专利与免疫调节和肌肉骨骼再生沃顿果冻细胞有关。

Recent patents on regenerative medicine Pub Date : 2013-01-01 DOI: 10.2174/22102965113039990020

Limin Wang, Mark L Weiss, Michael S Detamore

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引用次数: 4

Recent Progress on Chemical Biology of Pluripotent Stem Cell Self-renewal, Reprogramming and Cardiomyogenesis. 多能干细胞自我更新、重编程和心肌形成的化学生物学研究进展。

Recent patents on regenerative medicine Pub Date : 2011-09-01 DOI: 10.2174/2210296511101030263

Jijun Hao, Douglas B Sawyer, Antonis K Hatzopoulos, Charles C Hong

引用次数: 13

Patents on Technologies of Human Tissue and Organ Regeneration from Pluripotent Human Embryonic Stem Cells 多能性人胚胎干细胞再生人体组织和器官技术专利

Recent patents on regenerative medicine Pub Date : 2011-05-01 DOI: 10.2174/2210297311101020142

Xuejun H. Parsons, Y. Teng, Dennis A. Moore, E. Snyder

{"title":"Patents on Technologies of Human Tissue and Organ Regeneration from Pluripotent Human Embryonic Stem Cells","authors":"Xuejun H. Parsons, Y. Teng, Dennis A. Moore, E. Snyder","doi":"10.2174/2210297311101020142","DOIUrl":"https://doi.org/10.2174/2210297311101020142","url":null,"abstract":"Human embryonic stem cells (hESCs) are genetically stable with unlimited expansion ability and unrestricted plasticity, proffering a pluripotent reservoir for in vitro derivation of a large supply of disease-targeted human somatic cells that are restricted to the lineage in need of repair. There is a large healthcare need to develop hESC-based therapeutic solutions to provide optimal regeneration and reconstruction treatment options for the damaged or lost tissue or organ that have been lacking. In spite of controversy surrounding the ownership of hESCs, the number of patent applications related to hESCs is growing rapidly. This review gives an overview of different patent applications on technologies of derivation, maintenance, differentiation, and manipulation of hESCs for therapies. Many of the published patent applications have been based on previously established methods in the animal systems and multi-lineage inclination of pluripotent cells through spontaneous germ-layer differentiation. Innovative human stem cell technologies that are safe and effective for human tissue and organ regeneration in the clinical setting remain to be developed. Our overall view on the current patent situation of hESC technologies suggests a trend towards hESC patent filings on novel therapeutic strategies of direct control and modulation of hESC pluripotent fate, particularly in a 3-dimensional context, when deriving clinically-relevant lineages for regenerative therapies.","PeriodicalId":89715,"journal":{"name":"Recent patents on regenerative medicine","volume":"1 1","pages":"142 - 163"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68159495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Patents on Technologies of Human Tissue and Organ Regeneration from Pluripotent Human Embryonic Stem Cells. 多能人胚胎干细胞人体组织和器官再生技术专利。

Recent patents on regenerative medicine Pub Date : 2011-01-01 DOI: 10.2174/2210296511101020142

Xuejun H Parsons, Yang D Teng, Dennis A Moore, Evan Y Snyder

{"title":"Patents on Technologies of Human Tissue and Organ Regeneration from Pluripotent Human Embryonic Stem Cells.","authors":"Xuejun H Parsons, Yang D Teng, Dennis A Moore, Evan Y Snyder","doi":"10.2174/2210296511101020142","DOIUrl":"10.2174/2210296511101020142","url":null,"abstract":"Human embryonic stem cells (hESCs) are genetically stable with unlimited expansion ability and unrestricted plasticity, proffering a pluripotent reservoir for in vitro derivation of a large supply of disease-targeted human somatic cells that are restricted to the lineage in need of repair. There is a large healthcare need to develop hESC-based therapeutic solutions to provide optimal regeneration and reconstruction treatment options for the damaged or lost tissue or organ that have been lacking. In spite of controversy surrounding the ownership of hESCs, the number of patent applications related to hESCs is growing rapidly. This review gives an overview of different patent applications on technologies of derivation, maintenance, differentiation, and manipulation of hESCs for therapies. Many of the published patent applications have been based on previously established methods in the animal systems and multi-lineage inclination of pluripotent cells through spontaneous germ-layer differentiation. Innovative human stem cell technologies that are safe and effective for human tissue and organ regeneration in the clinical setting remain to be developed. Our overall view on the current patent situation of hESC technologies suggests a trend towards hESC patent filings on novel therapeutic strategies of direct control and modulation of hESC pluripotent fate, particularly in a 3-dimensional context, when deriving clinically-relevant lineages for regenerative therapies.","PeriodicalId":89715,"journal":{"name":"Recent patents on regenerative medicine","volume":"1 2","pages":"142-163"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31284642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0