Journal of clinical research best practices最新文献

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Are Payments to Human Research Subjects Ethically Suspect? 支付给人类研究对象的费用在伦理上可疑吗?
David B Resnik
{"title":"Are Payments to Human Research Subjects Ethically Suspect?","authors":"David B Resnik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bioethicists and institutional review boards often worry that paying human subjects too much money for research participation might compromise informed consent by coercing or unduly influencing individuals to enroll in studies against their better judgment. However, empirical research does not support the hypothesis that payments adversely impact judgment and decision-making concerning research participation, and the opposite problem - underpayment - also raises significant ethical concerns, such as exploitation, and under-enrollment. In this article, I argue that our ethical qualms about the negative impact of money on decisions concerning research participation are largely unfounded and reflect more general concerns about the need to avoid repeating abuses of human subjects that occurred in the past. I shall also argue that the best way to promote the rights and welfare of human research subjects is to treat them as competent adults who have the capacity to make wise choices involving money. What this argument means in practice is that offering human subjects money for their participation should not be regarded as ethically suspect, absent substantial evidence to the contrary.</p>","PeriodicalId":89582,"journal":{"name":"Journal of clinical research best practices","volume":"15 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059779/pdf/nihms-1539207.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37717413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-Use Review and the IRB. 军民两用审查和内部审查委员会。
David B Resnik
{"title":"Dual-Use Review and the IRB.","authors":"David B Resnik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Given the growing threat of the misuse of biomedical research by terrorists or others, institutional review boards (IRBs) are likely to encounter research protocols that raise dual-use issues. While IRBs should be informed about these issues and should be prepared to address them, they should not be burdened with the responsibility of conducting their own dual-use review. A dual-use committee (DUC), institutional biosafety committee (IBC), or other committee should handle this task and convey its findings and recommendations to institutional officials.</p>","PeriodicalId":89582,"journal":{"name":"Journal of clinical research best practices","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259681/pdf/nihms220365.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30401604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social Benefits of Human Subjects Research. 人类受试者研究的社会效益。
David B Resnik
{"title":"Social Benefits of Human Subjects Research.","authors":"David B Resnik","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":89582,"journal":{"name":"Journal of clinical research best practices","volume":"4 11","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920587/pdf/nihms-175415.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32115438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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