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An RNA Sensor Platform for CTC Detection: Nanotechnology for Detection of Tumour Cell Marker RNAs. 用于 CTC 检测的 RNA 传感器平台：检测肿瘤细胞标记 RNA 的纳米技术。
BIOforum Europe : trends and techniques in life science research Pub Date : 2009-02-01
Gary A Clawson, Christine Keating, Rustom Bhiladvala, Weihua Pan, Theresa Mayer
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引用次数: 0
CANCER MUCOSA ANTIGENS A NOVEL PARADIGM IN CANCER IMMUNOTHERAPEUTICS. 癌症粘膜抗原是癌症免疫治疗的新范式。
BIOforum Europe : trends and techniques in life science research Pub Date : 2009-01-01
Adam E Snook, Scott A Waldman
{"title":"CANCER MUCOSA ANTIGENS A NOVEL PARADIGM IN CANCER IMMUNOTHERAPEUTICS.","authors":"Adam E Snook, Scott A Waldman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Employing antigens with expression restricted to normal intestinal mucosa and derivative colorectal tumors - cancer mucosa antigens (CMAs) - represents a novel paradigm in anti-tumor immunotherapy. Immune compartmentalization limits tolerance to CMAs and restricts mucosa-targeted autoimmunity, allowing safe and effective immunotherapy for metastatic colorectal cancer. Guanylyl cyclase C (GCC), an intestine/colorectal cancer-restricted protein, is poised for clinical evaluation as the index CMA.</p>","PeriodicalId":89092,"journal":{"name":"BIOforum Europe : trends and techniques in life science research","volume":"3 ","pages":"14-16"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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