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A Precision Medicine Approach to Dementia Care: Syndrome, Etiology, and Copathology. 痴呆症护理的精准医学方法：综合征、病因学和共病理学
Practical neurology (Fort Washington, Pa.) Pub Date : 2023-07-01
D Luke Fischer, William W Seeley
{"title":"A Precision Medicine Approach to Dementia Care: Syndrome, Etiology, and Copathology.","authors":"D Luke Fischer, William W Seeley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recognizing multiple neuropathological entities in people with dementia improves understanding of diagnosis, prognosis, and expected outcomes from therapies. Care for the individual with dementia includes the evaluation and management of diseases associated with the aged brain, most commonly neurodegeneration and vascular brain injury (VBI). Terminology has evolved to keep pace with diagnostic, prognostic, and therapeutic advances, and autopsy studies have shown that multiple comorbid neuropathological entities are the rule, not the exception, especially in older individuals. With the advent of disease-modifying therapies, delivering dementia care requires an encompassing framework that allows clinicians to consider all of an individual's underlying diseases and their contributions to symptom burden. A diagnostic approach, common co-occurring pathologies, and implications for current and future clinical care are reviewed.</p>","PeriodicalId":74484,"journal":{"name":"Practical neurology (Fort Washington, Pa.)","volume":"2023 ","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399644/pdf/nihms-1915720.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10302296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychiatric Comorbidities in Functional Neurologic Symptom Disorder. 功能性神经症状障碍的精神病合并症。
Practical neurology (Fort Washington, Pa.) Pub Date : 2022-03-01
Victor German Patron, Yazmin Rustomji, Chadwick Yip, Lisanne Michelle Jenkins
{"title":"Psychiatric Comorbidities in Functional Neurologic Symptom Disorder.","authors":"Victor German Patron,&nbsp;Yazmin Rustomji,&nbsp;Chadwick Yip,&nbsp;Lisanne Michelle Jenkins","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Attachment deficits in the context of psychosocial factors may explain the presence of functional neurologic disorder.</p>","PeriodicalId":74484,"journal":{"name":"Practical neurology (Fort Washington, Pa.)","volume":"21 3","pages":"71-75"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836030/pdf/nihms-1818340.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9377548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Imaging Biomarkers in Dementia: Amyloid and tau PET imaging aids evaluation of patients suspected of having Alzheimer disease or other dementias. 痴呆症的分子成像生物标志物:淀粉样蛋白和tau PET成像有助于评估怀疑患有阿尔茨海默病或其他痴呆症的患者。
Practical neurology (Fort Washington, Pa.) Pub Date : 2020-11-01
Brad Dickerson, Alireza Atri
{"title":"Molecular Imaging Biomarkers in Dementia: Amyloid and tau PET imaging aids evaluation of patients suspected of having Alzheimer disease or other dementias.","authors":"Brad Dickerson,&nbsp;Alireza Atri","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74484,"journal":{"name":"Practical neurology (Fort Washington, Pa.)","volume":"19 9","pages":"34-45"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387980/pdf/nihms-1677163.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39363589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Cognitive Assessments for Dementia: Digital assessments may enhance the efficiency of evaluations in neurology and other clinics. 痴呆症的数字认知评估:数字评估可以提高神经病学和其他诊所的评估效率。
Practical neurology (Fort Washington, Pa.) Pub Date : 2020-11-01
Adam M Staffaroni, Elena Tsoy, Jack Taylor, Adam L Boxer, Katherine L Possin
{"title":"Digital Cognitive Assessments for Dementia: Digital assessments may enhance the efficiency of evaluations in neurology and other clinics.","authors":"Adam M Staffaroni,&nbsp;Elena Tsoy,&nbsp;Jack Taylor,&nbsp;Adam L Boxer,&nbsp;Katherine L Possin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74484,"journal":{"name":"Practical neurology (Fort Washington, Pa.)","volume":"2020 ","pages":"24-45"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078574/pdf/nihms-1656445.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38931742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyotrophic Lateral Sclerosis: Integrated care provides the best quality of life. 肌萎缩侧索硬化症：综合护理提供最佳生活质量。
Practical neurology (Fort Washington, Pa.) Pub Date : 2019-07-01
Jonathan R Brent, Senda Ajroud-Driss
{"title":"Amyotrophic Lateral Sclerosis: Integrated care provides the best quality of life.","authors":"Jonathan R Brent, Senda Ajroud-Driss","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74484,"journal":{"name":"Practical neurology (Fort Washington, Pa.)","volume":"18 ","pages":"46-49"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978460/pdf/nihms-1676127.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25501926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosing and Treating Co-morbid Sleep Apnea in Neurological Disorders, Part II. 诊断和治疗神经系统疾病共病睡眠呼吸暂停，第二部分。
Practical neurology (Fort Washington, Pa.) Pub Date : 2010-09-01
Erik K St Louis
{"title":"Diagnosing and Treating Co-morbid Sleep Apnea in Neurological Disorders, Part II.","authors":"Erik K St Louis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74484,"journal":{"name":"Practical neurology (Fort Washington, Pa.)","volume":"9 5","pages":"26-31"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716573/pdf/nihms457492.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31240571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosing And Treating Co-Morbid Sleep Apnea In Neurological Disorders. 神经系统疾病共病性睡眠呼吸暂停的诊断和治疗。
Practical neurology (Fort Washington, Pa.) Pub Date : 2010-07-01
Erik K St Louis
{"title":"Diagnosing And Treating Co-Morbid Sleep Apnea In Neurological Disorders.","authors":"Erik K St Louis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74484,"journal":{"name":"Practical neurology (Fort Washington, Pa.)","volume":"9 4","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268511/pdf/nihms228640.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30430523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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