{"title":"Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation.","authors":"Guobao Feng, Lu Liu, Wanzhao Cui, Fang Wang","doi":"10.1088/1674-1056/ab7dac","DOIUrl":"10.1088/1674-1056/ab7dac","url":null,"abstract":"<p><p>The novel coronavirus pneumonia triggered by COVID-19 is now raging the whole world. As a rapid and reliable killing COVID-19 method in industry, electron beam irradiation can interact with virus molecules and destroy their activity. With the unexpected appearance and quickly spreading of the virus, it is urgently necessary to figure out the mechanism of electron beam irradiation on COVID-19. In this study, we establish a virus structure and molecule model based on the detected gene sequence of Wuhan patient, and calculate irradiated electron interaction with virus atoms via a Monte Carlo simulation that track each elastic and inelastic collision of all electrons. The characteristics of irradiation damage on COVID-19, atoms' ionizations and electron energy losses are calculated and analyzed with regions. We simulate the different situations of incident electron energy for evaluating the influence of incident energy on virus damage. It is found that under the major protecting of an envelope protein layer, the inner RNA suffers the minimal damage. The damage for a ∼100-nm-diameter virus molecule is not always enhanced by irradiation energy monotonicity, for COVID-19, the irradiation electron energy of the strongest energy loss damage is 2 keV.</p>","PeriodicalId":72585,"journal":{"name":"Chinese physics B = Zhongguo wu li B","volume":"29 4","pages":"048703"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10165316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yao Xu, Chun-Hui Zhang, Ernst Niebur, Jun-Song Wang
{"title":"Analytically determining frequency and amplitude of spontaneous alpha oscillation in Jansen's neural mass model using the describing function method.","authors":"Yao Xu, Chun-Hui Zhang, Ernst Niebur, Jun-Song Wang","doi":"10.1088/1674-1056/27/4/048701","DOIUrl":"10.1088/1674-1056/27/4/048701","url":null,"abstract":"<p><p>Spontaneous alpha oscillations are a ubiquitous phenomenon in the brain and play a key role in neural information processing and various cognitive functions. Jansen's neural mass model (NMM) was initially proposed to study the origin of alpha oscillations. Most of previous studies of the spontaneous alpha oscillations in the NMM were conducted using numerical methods. In this study, we aim to propose an analytical approach using the describing function method to elucidate the spontaneous alpha oscillation mechanism in the NMM. First, the sigmoid nonlinear function in the NMM is approximated by its describing function, allowing us to reformulate the NMM and derive its standard form composed of one nonlinear part and one linear part. Second, by conducting a theoretical analysis, we can assess whether or not the spontaneous alpha oscillation would occur in the NMM and, furthermore, accurately determine its amplitude and frequency. The results reveal analytically that the interaction between linearity and nonlinearity of the NMM plays a key role in generating the spontaneous alpha oscillations. Furthermore, strong nonlinearity and large linear strength are required to generate the spontaneous alpha oscillations.</p>","PeriodicalId":72585,"journal":{"name":"Chinese physics B = Zhongguo wu li B","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/1674-1056/27/4/048701","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39254604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liu Yan-Song, Yi Fu, Ramachandram Badugu, Joseph R Lakowicz, Xu Xiao-Liang
{"title":"Nanoscaled ZnO films used as enhanced substrates for fluorescence detection of dyes.","authors":"Liu Yan-Song, Yi Fu, Ramachandram Badugu, Joseph R Lakowicz, Xu Xiao-Liang","doi":"10.1088/1674-1056/21/3/037803","DOIUrl":"10.1088/1674-1056/21/3/037803","url":null,"abstract":"<p><p>The ability of nanoscaled ZnO films to enhance fluorescence was studied. We found that the fluorescence intensities of Cy5, rhodamine 6G, and fluorescein can be enhanced about 10-fold on nanoscaled ZnO films as compared to that on glass substrates. The lifetimes of all samples were measured, and no obvious change in lifetime was observed for dyes on different substrates. The mechanism for the nanoscaled ZnO film enhanced fluorescence appears to be different from that for the metal-fluorophore systems.</p>","PeriodicalId":72585,"journal":{"name":"Chinese physics B = Zhongguo wu li B","volume":"21 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025740/pdf/nihms-1052239.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}