... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference最新文献

Early Detection of Rapid Cystic Fibrosis Disease Progression Tailored to Point of Care: A Proof-of-Principle Study. 针对护理点的快速囊性纤维化疾病进展的早期检测:一项原理验证研究

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2017-11-01 Epub Date: 2017-12-21 DOI: 10.1109/HIC.2017.8227620

Rhonda Szczesniak, Cole Brokamp, Weiji Su, Gary L McPhail, John Pestian, John P Clancy

{"title":"Early Detection of Rapid Cystic Fibrosis Disease Progression Tailored to Point of Care: A Proof-of-Principle Study.","authors":"Rhonda Szczesniak, Cole Brokamp, Weiji Su, Gary L McPhail, John Pestian, John P Clancy","doi":"10.1109/HIC.2017.8227620","DOIUrl":"https://doi.org/10.1109/HIC.2017.8227620","url":null,"abstract":"Slowing cystic fibrosis (CF) lung disease progression is crucial to survival, but point-of-care technologies aimed at early detection-and possibly prevention-of rapid lung function decline are limited. This proof-of-principle study leverages a rich national patient registry and follow-up data on a local CF cohort to build an algorithm and prototype prognostic tool aimed at early detection of rapid lung function decline. The algorithm was developed using a novel longitudinal analysis of lung function (measured as forced expiratory volume in 1 s of % predicted, FEV1). Covariates included clinical and demographic characteristics selected from the registry based on information criterion. Preliminary assessment of algorithm performance suggested excellent predictive accuracy and earlier detection of rapid decline than standard of care being applied at a local center. Graphical displays were presented and evaluated for clinical utility. Predictions from the algorithms and chosen graphical displays were translated into a prototype web application using RShiny and underwent iterative development based on clinician feedback. This paper suggests that the algorithm and its translation could offer a means for earlier detection and treatment of rapid decline, providing clinicians with a viable point-of-care technology to intervene prior to irreversible lung damage.","PeriodicalId":72020,"journal":{"name":"... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/HIC.2017.8227620","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35957551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Pharmacodynamic modeling of propofol-induced general anesthesia in young adults. 异丙酚诱导青少年全身麻醉的药效学模型。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2017-11-01 Epub Date: 2017-12-21 DOI: 10.1109/hic.2017.8227580

Sourish Chakravarty, Ksenia Nikolaeva, Devika Kishnan, Francisco J Flores, Patrick L Purdon, Emery N Brown

{"title":"Pharmacodynamic modeling of propofol-induced general anesthesia in young adults.","authors":"Sourish Chakravarty, Ksenia Nikolaeva, Devika Kishnan, Francisco J Flores, Patrick L Purdon, Emery N Brown","doi":"10.1109/hic.2017.8227580","DOIUrl":"https://doi.org/10.1109/hic.2017.8227580","url":null,"abstract":"Target controlled infusion (TCI) of intraveneous anesthetics can assist clinical practitioners to provide improved care for General Anesthesia (GA). Pharmacokinetic/Pharmacodynamic (PK/PD) models help in relating the anesthetic drug infusion to observed brain activity inferred from electroencephalogram (EEG) signals. The parameters in popular population PK/PD models for propofol-induced GA (Marsh and Schnider models) are either verified based on proprietary functions of the EEG signal which are difficult to correlate with the neurophysiological models of anesthesia, or the marker itself needs to be estimated simultaneously with the PD model. Both these factors make these existing paradigms challenging to apply in real-time context where a patient-specific tuning of parameters is desired. In this work, we propose a simpler EEG marker from frequency domain description of EEG and develop two corresponding PK/PD modeling approaches which differ in whether they use existing population-level PK models (approach 1) or not (approach 2). We use a simple deterministic parameter estimation approach to identify the unknown PK/PD model parameters from an existing human EEG data-set. We infer that both approaches 1 and 2 yield similar and reasonably good fits to the marker data. This work can be useful in developing patient-specific TCI strategies to induce GA.","PeriodicalId":72020,"journal":{"name":"... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/hic.2017.8227580","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38279841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Formant Frequency-based Speech Enhancement Technique to improve Intelligibility for hearing aid users with smartphone as an assistive device. 基于共振频率的语音增强技术提高智能手机助听器用户的可理解性。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2017-11-01 Epub Date: 2017-12-21 DOI: 10.1109/hic.2017.8227577

Gautam S Bhat, Nikhil Shankar, Chandan K A Reddy, Issa M S Panahi

{"title":"Formant Frequency-based Speech Enhancement Technique to improve Intelligibility for hearing aid users with smartphone as an assistive device.","authors":"Gautam S Bhat, Nikhil Shankar, Chandan K A Reddy, Issa M S Panahi","doi":"10.1109/hic.2017.8227577","DOIUrl":"https://doi.org/10.1109/hic.2017.8227577","url":null,"abstract":"In this paper, we present a Speech Enhancement (SE) method implemented on a smartphone, and this arrangement functions as an assistive device to hearing aids (HA). Many benchmark single channel SE algorithms implemented on HAs provide considerable improvement in speech quality, while speech intelligibility improvement still remains a prime challenge. The proposed SE method based on Log spectral amplitude estimator improves speech intelligibility in the noisy real world acoustic environment using the priori information of formant frequency locations. The formant frequency information avails us to control the amount of speech distortion in these frequency bands, thereby controlling speech distortion. We introduce a 'scaling' parameter for the SE gain function, which controls the gains over the non-formant frequency band, allowing the HA users to customize the playback speech using a smartphone application to their listening preference. Objective intelligibility measures show the effectiveness of the proposed SE method. Subjective results reflect the suitability of the developed Speech Enhancement application in real-world noisy conditions at SNR levels of -5 dB, 0 dB and 5 dB.","PeriodicalId":72020,"journal":{"name":"... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/hic.2017.8227577","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38186491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Agile Co-Development for Clinical Adoption and Adaptation of Innovative Technologies. 临床采用和适应创新技术的敏捷协同开发。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2017-11-01 DOI: 10.1109/HIC.2017.8227583

Vaishnavi Kannan, Mujeeb A Basit, Josh E Youngblood, Trenton D Bryson, Seth M Toomay, Jason S Fish, Duwayne L Willett

{"title":"Agile Co-Development for Clinical Adoption and Adaptation of Innovative Technologies.","authors":"Vaishnavi Kannan, Mujeeb A Basit, Josh E Youngblood, Trenton D Bryson, Seth M Toomay, Jason S Fish, Duwayne L Willett","doi":"10.1109/HIC.2017.8227583","DOIUrl":"https://doi.org/10.1109/HIC.2017.8227583","url":null,"abstract":"Even the most innovative healthcare technologies provide patient benefits only when adopted by clinicians and/or patients in actual practice. Yet realizing optimal positive impact from a new technology for the widest range of individuals who would benefit remains elusive. In software and new product development, iterative rapid-cycle \"agile\" methods more rapidly provide value, mitigate failure risks, and adapt to customer feedback. Co-development between builders and customers is a key agile principle. But how does one accomplish co-development with busy clinicians? In this paper, we discuss four practical agile co-development practices found helpful clinically: (1) User stories for lightweight requirements; (2) Time-boxed development for collaborative design and prompt course correction; (3) Automated acceptance test driven development, with clinician-vetted specifications; and (4) Monitoring of clinician interactions after release, for rapid-cycle product adaptation and evolution. In the coming wave of innovation in healthcare apps ushered in by open APIs to EHRs, learning rapidly what new product features work well for clinicians and patients will become even more crucial.","PeriodicalId":72020,"journal":{"name":"... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/HIC.2017.8227583","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36664543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Multivariate Voronoi Outlier Detection for Time Series. 时间序列的多变量Voronoi离群值检测。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2014-10-01 DOI: 10.1109/HIC.2014.7038934

Chris E Zwilling, Michelle Yongmei Wang

引用次数: 5

Feasibility of a hybrid elastographic-microfluidic device to rapidly process and assess pancreatic cancer biopsies for pathologists. 为病理学家快速处理和评估胰腺癌活检的混合弹性成像-微流控装置的可行性。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2014-10-01 DOI: 10.1109/HIC.2014.7038927

Ronnie Das, Thu-Mai Nguyen, Saniel D Lim, Matt O'Donnell, Ruikang K Wang, Eric J Seibel

{"title":"Feasibility of a hybrid elastographic-microfluidic device to rapidly process and assess pancreatic cancer biopsies for pathologists.","authors":"Ronnie Das, Thu-Mai Nguyen, Saniel D Lim, Matt O'Donnell, Ruikang K Wang, Eric J Seibel","doi":"10.1109/HIC.2014.7038927","DOIUrl":"10.1109/HIC.2014.7038927","url":null,"abstract":"In this study, our collaborative research group explored the possibility of incorporating ultrasound elastography technology with a microfluidic device that is designed to prepare fine needle core biopsies (CBs; L=0.5-2.0 cm, D=0.4-1.2 mm) for pancreatic cancer diagnosis. For the first time, elastographic techniques were employed to measure shear wave velocity in fresh (3.7 m/s) and formalin-fixed (14.7 m/s) pancreatic CBs. Shear wave velocity did not vary whether fixed specimens were free on a microscope slide, or constrained within glass microfluidic channels: 11.5±1.9 v. 11.8±2.1 m/s. 4% agarose inclusions were also embedded within 1% agarose hydrogels to simulate cysts, neoplastic, or necrotic tissue within CBs. Inclusions were successfully visualized and measured using optical coherence elastography. These preliminary experiments demonstrate in a rudimentary fashion that elastographic measurements of pancreatic CBs may be incorporated with our microfluidic device. The rapid mapping of CB stiffness may provide qualitative spatial information for pathologists to determine a more accurate diagnosis for patients.","PeriodicalId":72020,"journal":{"name":"... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/HIC.2014.7038927","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33419691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Med-vest: A wearable sensory platform. Med-vest:一种可穿戴的传感平台。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2014-10-01 Epub Date: 2015-02-12 DOI: 10.1109/HIC.2014.7038909

R A Durfee, J Venugopalan, Jiacheng Ren, M D Wang

引用次数: 1

Low-Cost Disposable Cartridge for Performing a White Blood Cell Count and Partial Differential at the Point-of-Care. 低成本的一次性药筒用于执行白细胞计数和在护理点的部分差异。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2014-10-01 DOI: 10.1109/HIC.2014.7038862

Catherine E Majors, Michal E Pawlowski, Tomasz Tkaczyk, Rebecca R Richards-Kortum

{"title":"Low-Cost Disposable Cartridge for Performing a White Blood Cell Count and Partial Differential at the Point-of-Care.","authors":"Catherine E Majors, Michal E Pawlowski, Tomasz Tkaczyk, Rebecca R Richards-Kortum","doi":"10.1109/HIC.2014.7038862","DOIUrl":"https://doi.org/10.1109/HIC.2014.7038862","url":null,"abstract":"Being able to perform a white blood cell (WBC) count and differential is a crucial laboratory test for basic diagnostic practices. In this paper, we demonstrate proof of concept results for a disposable cartridge that could be used to perform a WBC count and 3-part differential at the point-of-care. The cartridge is composed of a glass slide, a layer of transfer tape, and a glass cover slip and incorporates acridine orange for cell staining and sub-type differentiation; the stained blood is then imaged, and image analysis techniques return a WBC count and 3-part differential. The cartridge was tested on a laboratory microscope with 3 normal samples, and had promising results with 85.7% of images resulting in a WBC count with ±15% of the true value. Further, the 3-part differential concentrations determined using the disposable cartridge had strong correlations with the true concentrations (R2 values of 0.9986, 0.9421, and 0.6942 for granulocytes, lymphocytes, and monocytes, respectively). Preliminary designs for a low-cost, portable microscope have been created and are currently being prototyped.","PeriodicalId":72020,"journal":{"name":"... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/HIC.2014.7038862","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9709158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Design and Performance of a Low-Cost, Handheld Reader for Diagnosing Anemia in Blantyre, Malawi. 马拉维布兰太尔低成本贫血诊断手持阅读器的设计与性能。

... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference Pub Date : 2014-10-01 DOI: 10.1109/HIC.2014.7038926

Meaghan Bond, Jessica Mvula, Elizabeth Molyneux, Rebecca Richards-Kortum

{"title":"Design and Performance of a Low-Cost, Handheld Reader for Diagnosing Anemia in Blantyre, Malawi.","authors":"Meaghan Bond, Jessica Mvula, Elizabeth Molyneux, Rebecca Richards-Kortum","doi":"10.1109/HIC.2014.7038926","DOIUrl":"https://doi.org/10.1109/HIC.2014.7038926","url":null,"abstract":"Anemia, a condition characterized by insufficient hemoglobin, affects 56.2% of pregnant women and 66.1% of children under five in low-resource countries. Though hemoglobin concentration measurement is the most common laboratory test in the world, the high cost of disposables (>$1.00 per test in Malawi) limits its availability in these settings. We have demonstrated a spectrophotometric method that reduces the per-test cost of anemia diagnosis to under $0.01 by using chromatography paper as the only disposable. Improvements in the hand-held reader, including using laser modules and a reference photodiode, enabled repeatable results within and across devices. We evaluated this method by analyzing capillary blood samples from 70 patients in the pediatric ward of Queen Elizabeth Central Hospital, Blantyre, Malawi. ~90% of these samples were within 2 g/dL of the standard value, with higher accuracy on more anemic samples. Current work aims to improve this accuracy by converting the hemoglobin in the sample to the more stable form methemoglobin.","PeriodicalId":72020,"journal":{"name":"... Health innovations and point-of-care technologies conference. Health innovations and point-of-care technologies conference","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/HIC.2014.7038926","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9709160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9