放射学期刊(英文)Pub Date : 2017-03-01Epub Date: 2017-03-24DOI: 10.4236/ojrad.2017.71004
Xue Bai, Ashley D Harris, Tao Gong, Nicolaas A J Puts, Guangbin Wang, Michael Schär, Peter B Barker, Richard A E Edden
{"title":"Voxel Placement Precision for GABA-Edited Magnetic Resonance Spectroscopy.","authors":"Xue Bai, Ashley D Harris, Tao Gong, Nicolaas A J Puts, Guangbin Wang, Michael Schär, Peter B Barker, Richard A E Edden","doi":"10.4236/ojrad.2017.71004","DOIUrl":"https://doi.org/10.4236/ojrad.2017.71004","url":null,"abstract":"<p><p>The purpose of the present study was to assess the reproducibility of voxel placement for GABA-edited MRS. GABA-edited MRS data were acquired in 13 healthy volunteers from (3 cm)<sup>3</sup> voxel; and within the same session a second acquisition was independently prescribed. A three-dimensional voxel mask image was reconstructed in T1-image-space using the SVMask tool (in house software). Reproducibility of voxel placement was assessed using the Dice overlap coefficient, both within-subject and between-subject following co-registration of T1 images and transformation of voxel mask images to standard space. Within-subject overlap coefficients were 86% ± 5%. Between-subject overlap coefficients were 75% ± 10%. For the two voxel locations considered (occipital and sensorimotor), voxel overlap was very similar. Between-subject values are higher due to between-session effects, anatomical variability and volume mismatch in standard space. While surprisingly low in terms of volume overlap, the overlap coefficients correspond to acceptable linear displacements.</p>","PeriodicalId":71338,"journal":{"name":"放射学期刊(英文)","volume":"7 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35155392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}