健康科学:英文版最新文献

{"title":"Novel Cancer Treatment Using Targeted Delivery of Short-Lived Radiologically Activated Nanoparticles.","authors":"P L Andrade, J B Leão","doi":"10.17265/2328-7136/2019.01.008","DOIUrl":"10.17265/2328-7136/2019.01.008","url":null,"abstract":"<p><p>The goal of our preliminary study is to show that a minimal of overall body toxicity while maximizing the cancer tumor treatment may be achieved in a novel approach where minute amounts of coated nanoparticles may be radiologically activated prior to treatment and \"coerce\" tumor cells into readily absorb these nanoparticles. This targeted intracytoplasmic delivery of short-lived radiologically activated nanoparticles could provide less \"whole-body\" radiation dose while delivering a short lived potent tumor localized dose, along with their low toxicity may prove to be another tool in the treatment of diverse cancers.</p>","PeriodicalId":70372,"journal":{"name":"健康科学:英文版","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395374/pdf/nihms-1918447.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9945550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Factors Associated with Low Birth Weight among Teenage Mothers in New Mulago Hospital: A Cross Sectional Study.","authors":"Bayo Louis,&nbsp;Buyungo Steven,&nbsp;Nakiwala Margret,&nbsp;Nabimba Ronald,&nbsp;Luyinda Emmanuel,&nbsp;Nsubuga Tadeo,&nbsp;Imelda Namagembe,&nbsp;Arabat Kasangaki,&nbsp;Banura Cecily","doi":"10.17265/2328-7136/2016.04.003","DOIUrl":"https://doi.org/10.17265/2328-7136/2016.04.003","url":null,"abstract":"<p><p>The World Health Organization defines low birth weight (LBW) as a new born having a weight of less than 2,500 g at birth. Low birth weight is one of the major determinants of perinatal survival, infant morbidity and mortality as well as the risk of developmental disabilities and illnesses in future lives. WHO estimates that about 30 million low birth weight babies are born annually (23.4% of all births) and they often face short and long term health consequences. Whereas the global prevalence of LBW has slightly declined, the rate in many developing countries is still quite high. In Uganda, low birth weight among teenage mothers is a problem. Our study aimed to estimate the prevalence of and identify the factors associated with low birth weight among teenage mothers in New Mulago hospital. We conducted an analytical cross sectional study among teenage mothers who delivered from new Mulago Hospital Complex labour suite from August 2013 to August 2014. Trained interviewers, administered pre-tested questionnaires to consecutive mothers to obtain information on their socio-demographic characteristics, obstetric history and child factors. Odds ratios and <i>P</i>-values were calculated to determine the relationship between independent and dependent variables. We also used descriptive statistics for the quantitative data. A total of 357 teenage mothers were enrolled on the study. Their mean age was 18 years (Range 13-19), majority, 98.4% aged 15-19 years. The prevalence of LBW was 25.5%. Pre-term delivery (OR = 3.3032 <i>P</i> = 0.0001) and multiple pregnancies (OR = 0.165 <i>P</i> = 0.039) were associated with LBW. Malaria, young maternal age and ANC attendance were not associated with LBW. Child factors such as birth order, congenital anomalies and sex of the baby were also not associated with LBW. The prevalence of LBW is high among teenage mothers, pre-term delivery and multiple pregnancies were associated factors with LBW. Health professional's need to address teenage maternal health. Health workers should encourage teenage mothers to attend focused antenatal care as recommended by the Uganda ministry of Health. A specialized maternal facility centre that is friendly for adolescent/teenage mothers is advisable so as to improve on completion rates and capture high risk teenage mothers early.</p>","PeriodicalId":70372,"journal":{"name":"健康科学:英文版","volume":"4 ","pages":"192-199"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775522/pdf/nihms930957.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35758514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare Cost of Smoking Induced Cardiovascular Disease in Tanzania.","authors":"Asmerom Kidane, Aloyce Hepelwa, Ernest Tingum Ngeh, Teh-Wei Hu","doi":"10.17265/2328-7136/2015.03.003","DOIUrl":"10.17265/2328-7136/2015.03.003","url":null,"abstract":"<p><p>The study presented here estimates the total health care cost attributable to smoking induced cardiovascular disease in Tanzania. The study based on a survey conducted at a referral university hospital in Dar es Salaam in 2014. Assuming a 2% prevalence rate of cardiovascular disease and a population of 47.2 million, it was estimated that there are 943,800 cardiovascular patients in Tanzania. The proportion of ever smokers among the surveyed patients was found to be 25 percent yielding 240,400 patients who suffer from smoking induced cardiovascular diseases. Per capita annual expenditure per patient is estimated to be 566.6 US dollars and total annual expenditure for the country was estimated to be 136.1 million US dollars. On a per capita basis more direct and indirect cost is incurred on males compared to females; more is spent on the elderly (40 or more years) compared to the youth (less than 20 years). When compared with the mean annual household income of the surveyed population, the smoking induced per capita expenditure constitutes 35% of household income.</p>","PeriodicalId":70372,"journal":{"name":"健康科学:英文版","volume":"3 3","pages":"117-122"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853883/pdf/nihms780113.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34461824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}