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比较莫西沙星与左氧氟沙星在治疗呼吸道感染的有效性 比较莫西沙星与左氧氟沙星在治疗呼吸道感染的有效性
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx1210
振东 李
{"title":"比较莫西沙星与左氧氟沙星在治疗呼吸道感染的有效性","authors":"振东 李","doi":"10.61654/zzyskx1210","DOIUrl":"https://doi.org/10.61654/zzyskx1210","url":null,"abstract":"目的:比较莫西沙星与左氧氟沙星在治疗呼吸道感染的有效性。方法:于2024年09月-2025年08月期间,选取84例呼吸道感染患者为研究对象,数字随机表法将患者分为两组,其中对照组左氧氟沙星治疗,观察组予以莫西沙星治疗,对比治疗效果。结果:观察组较对照组治疗效果更加显著(P＜0.05);观察组较对照组临床症状消失时间明显缩短(P＜0.05);观察组较对照组炎性因子水平明显降低(P＜0.05);观察组较对照组不良反应发生率较低(P＜0.05)。结论:在治疗呼吸道感染中,莫西沙星的治疗效果更加显著,可有效缓解疾病症状、降低炎性因子水平,且莫西沙星的用药安全性更高。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147899767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
肿瘤微环境响应性纳米药物载体的制备及其靶向治疗效果评估 肿瘤微环境响应性纳米药物载体的制备及其靶向治疗效果评估
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx1202
庆茹 宋
{"title":"肿瘤微环境响应性纳米药物载体的制备及其靶向治疗效果评估","authors":"庆茹 宋","doi":"10.61654/zzyskx1202","DOIUrl":"https://doi.org/10.61654/zzyskx1202","url":null,"abstract":"基于肿瘤微环境响应性纳米药物载体在肿瘤治疗中的巨大应用前景,本文综述了近几年来基于肿瘤微环境响应性纳米药物载体的研究进展。重点介绍了一些具有肿瘤微环境响应性的纳米药物载体,如:基于肿瘤微环境响应性的纳米载体、基于肿瘤细胞与内皮细胞响应性的纳米载体等,并对其在生物医学领域的应用前景进行了展望。此外,还介绍了一些针对不同类型肿瘤微环境响应性纳米药物载体的研究进展,如:针对肝癌、肺癌等不同类型肿瘤微环境响应性纳米药物载体。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147897574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
单、双侧经皮椎体成形术对骨质疏松性椎体压缩性骨折的近期疗效分析 单、双侧经皮椎体成形术对骨质疏松性椎体压缩性骨折的近期疗效分析
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx0120
志斌 张, 国华 李
{"title":"单、双侧经皮椎体成形术对骨质疏松性椎体压缩性骨折的近期疗效分析","authors":"志斌 张, 国华 李","doi":"10.61654/zzyskx0120","DOIUrl":"https://doi.org/10.61654/zzyskx0120","url":null,"abstract":"目的:比较单、双侧经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩性骨折的疗效。方法:回顾性分析2018年1月至2022年3月行PVP的70例患者,分为单侧组(36例)和双侧组(34例),比较手术时间、住院费用、骨水泥用量及术前、术后1、6个月VAS和ODI评分。结果:两组术前VAS和ODI差异无统计学意义(P＞0.05)。双侧组术后VAS和ODI改善优于单侧组(P＜0.05),但手术时间及住院费用较高(P＜0.05)。结论:双侧PVP长期疗效更佳,单侧PVP具有手术时间短、费用低的优势,均具临床应用价值。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147884644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
基于代谢当量的康复护理对老年慢性心力衰竭患者生活质量和心肺功能的影响 基于代谢当量的康复护理对老年慢性心力衰竭患者生活质量和心肺功能的影响
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx2404
梦洁 盛, 雅梅 毛
{"title":"基于代谢当量的康复护理对老年慢性心力衰竭患者生活质量和心肺功能的影响","authors":"梦洁 盛, 雅梅 毛","doi":"10.61654/zzyskx2404","DOIUrl":"https://doi.org/10.61654/zzyskx2404","url":null,"abstract":"目的:探讨基于代谢当量(Metabolic Equivalent of Task, METs)的康复护理服务模式在老年慢性心力衰竭患者中的应用价值及其对生活质量(MLHFQ评分)和心肺功能的影响。方法:将40例老年慢性心力衰竭(Chronic Heart Failure, CHF)患者随机分为试验组(METs康复护理,n=20)和对照组(常规护理,n=20)。试验组接受个体化运动处方(依据心功能分级设定METs强度)、心理干预及远程康复指导。比较两组患者干预前后的明尼苏达心力衰竭生活质量问卷(MLHFQ)评分、6分钟步行试验(6MWT)距离及心肺运动试验指标(公斤摄氧量[VO2/kg]、最大摄氧量[VO2max]、运动中分钟通气量[VE])。结果:结果显示,干预后,试验组患者的MLHFQ各维度评分及总分显著低于对照组(均P<0.05);6MWT距离、VO2/kg、VO2max、VE均显著高于对照组(均P<0.05)。结论:基于METs的康复护理服务模式的合理执行与落实,具有显著的临床应用价值。尤其是将其应用在老年慢性心力衰竭病人护理中,能够有效改善患者的心肺功能。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
调经促孕丸联合来曲唑用于多囊卵巢综合征患者促排卵的临床疗效研究 调经促孕丸联合来曲唑用于多囊卵巢综合征患者促排卵的临床疗效研究
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx1207
杰媚 廖
{"title":"调经促孕丸联合来曲唑用于多囊卵巢综合征患者促排卵的临床疗效研究","authors":"杰媚 廖","doi":"10.61654/zzyskx1207","DOIUrl":"https://doi.org/10.61654/zzyskx1207","url":null,"abstract":"目的:探究调经促孕丸联合来曲唑治疗多囊卵巢综合征(PCOS)患者疗效。方法:选取84例PCOS患者,随机均分为对照组和观察组,每组42例。对照组采用来曲唑治疗,观察组采用调经促孕丸联合来曲唑治疗。对比两组患者的卵泡发育相关指标、性激素水平以及妊娠相关指标。结果:观察组在卵泡发育、性激素水平调节以及妊娠相关指标方面优于对照组(P<0.05)。结论:调经促孕丸联合曲唑治疗PCOS患者促排卵具有优质的临床疗效。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
不同免疫检验方法在乙型肝炎患者血清标志物检测中的应用分析 不同免疫检验方法在乙型肝炎患者血清标志物检测中的应用分析
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx0305
正力 于, 伟生 尹
{"title":"不同免疫检验方法在乙型肝炎患者血清标志物检测中的应用分析","authors":"正力 于, 伟生 尹","doi":"10.61654/zzyskx0305","DOIUrl":"https://doi.org/10.61654/zzyskx0305","url":null,"abstract":"目的:分析不同免疫检验方法在乙型肝炎患者血清标志物检测中的应用效果,评估其临床诊断准确性与实用性。因乙型肝炎是全球性公共卫生问题,准确检测血清标志物对病情评估和治疗方案选择很重要,本研究通过比较不同方法的敏感性、特异性及检出率探讨其临床价值。方法:选取我院2023年5月-2024年5月收治的120例乙型肝炎患者,按检测方法分为观察组和对照组。观察组用酶联免疫吸附法(ELISA)检测HBsAg、HBeAg、HBcAb等血清标志物,对照组用化学发光免疫分析法(CLIA)。记录并比较两组血清标志物检出率、检测时间及成本效益,用SPSS25.0软件分析数据,卡方检验方法间差异,P<0.05有统计学意义。结果:120例患者中,ELISA方法HBsAg、HBeAg、HBcAb检出率分别为95.8%(57/60)、90.4%(54/60)、88.3%(53/60);CLIA方法相应检出率分别为98.3%(59/60)、93.2%(56/60)、91.7%(55/60)。结论:不同免疫检验方法各有优势,化学发光免疫分析法(CLIA)灵敏度和特异性高,适用于需快速准确结果的场合;酶联免疫吸附法(ELISA)成本低,但特异性和检测速度欠佳。应根据临床需求合理选法,提高乙型肝炎诊疗效果。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147892896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
动态心电图检查技术应用于急性心肌梗死冠心病患者心律失常诊断中对其疾病检出率的影响 动态心电图检查技术应用于急性心肌梗死冠心病患者心律失常诊断中对其疾病检出率的影响
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx0108
长林 潘, 珂 马
{"title":"动态心电图检查技术应用于急性心肌梗死冠心病患者心律失常诊断中对其疾病检出率的影响","authors":"长林 潘, 珂 马","doi":"10.61654/zzyskx0108","DOIUrl":"https://doi.org/10.61654/zzyskx0108","url":null,"abstract":"目的:本文主要研究动态心电图(Holter ECG)对于急性心肌梗死(AMI)+冠心病患者心律失常检测的应用价值,通过对两种方法检测效能的比较分析,给临床心律失常管理及预后评价提供科学依据。方法:选择2025年1月至12月在我院住院治疗的急性心肌梗死合并冠心病患者共100例,随机分成两组,一组为观察组50例,用动态心电图监护,一组为对照组50例,常规心电图监护。对两组患者临床资料做统计分析,主要考察心律失常类型分布、发生频率以及检出效率,记录心功能指标和治疗药物使用情况的变化。结果:动态心电图组心律失常总检出率比对照组高很多,分别为76.00%和52.00%,差异有统计学意义(P<0.01)。结论:动态心电图技术比常规心电图具有更好的临床应用价值,可以提高对心律失常的早期发现和准确干预,从而降低并发症的发生率,并改善患者的预后。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147885888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
高压氧联合神经康复干预对创伤性脑损伤患者神经功能重塑的临床疗效及机制研究 高压氧联合神经康复干预对创伤性脑损伤患者神经功能重塑的临床疗效及机制研究
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx0111
洁 任
{"title":"高压氧联合神经康复干预对创伤性脑损伤患者神经功能重塑的临床疗效及机制研究","authors":"洁 任","doi":"10.61654/zzyskx0111","DOIUrl":"https://doi.org/10.61654/zzyskx0111","url":null,"abstract":"目的:分析对创伤性脑损伤患者神经功能重塑应用高压氧联合神经康复干预效果。方法:研究时间为2025年8月-2026年2月,将创伤性脑损伤患者共计60例纳入研究,随机抽签法分为对照组与观察组,对照组应用常规治疗措施,观察组采用高压氧联合神经康复干预措施,对两组患者临床疗效进行比较。结果:相比对照组,观察组患者临床疗效较高,P＜0.05。结论:对创伤性脑损伤患者神经功能重塑应用高压氧联合神经康复干预效果显著,能够有效提升患者临床疗效,所以该种干预措施值得推广。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147883604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
脉冲多普勒超声在胎儿宫内窘迫诊断中的效果 脉冲多普勒超声在胎儿宫内窘迫诊断中的效果
科学养生 Pub Date : 2025-01-01 DOI: 10.61654/zzyskx0106
明娟 王, 素涵 余
{"title":"脉冲多普勒超声在胎儿宫内窘迫诊断中的效果","authors":"明娟 王, 素涵 余","doi":"10.61654/zzyskx0106","DOIUrl":"https://doi.org/10.61654/zzyskx0106","url":null,"abstract":"目的:探讨分析对胎儿宫内窘迫应用脉冲多普勒超声进行诊断的效果。方法:选取2024年1月到2025年9月期间于我院接受产检的100例孕妇进行研究,其中确诊存在胎儿宫内窘迫的40例孕妇设为研究组,确认正常的60例孕妇为参照组。对两组均采用脉冲多普勒超声进行检查,对比检查结果。结果:研究组脐动脉收缩期最大血流速度与舒张末期血流速度比值较参照组更高,大脑中动脉搏动指数较参照组更低,对比均有统计学意义(P＜0.05)。结论:对胎儿宫内窘迫应用脉冲多普勒超声进行诊断,能够有效识别胎儿的异常情况,从而为确诊胎儿宫内窘迫提供确切依据,及时采取有效的处置措施,防止发生不良预后。","PeriodicalId":64792,"journal":{"name":"科学养生","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147892691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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