高校应用数学学报Pub Date : 2016-07-27DOI: 10.5455/medarh.2016.70.252-255
Aida Hamzic-Mehmedbasic
{"title":"Inflammatory Cytokines as Risk Factors for Mortality After Acute Cardiac Events.","authors":"Aida Hamzic-Mehmedbasic","doi":"10.5455/medarh.2016.70.252-255","DOIUrl":"10.5455/medarh.2016.70.252-255","url":null,"abstract":"<p><strong>Introduction: </strong>Inflammatory markers have been identified as potential indicators of future adverse outcome after acute cardiac events.</p><p><strong>Aim: </strong>This study aimed to analyze baseline inflammatory cytokines levels in patients with acute heart failure (AHF) and/or acute coronary syndrome (ACS) according to survival. The main objective was to identify risk factors for mortality after an episode of AHF and/or ACS.</p><p><strong>Methods: </strong>In this prospective longitudinal study 75 patients with the diagnosis of AHF and/or ACS were enrolled. Baseline laboratory and clinical data were retrieved. Serum and urine interleukin-6 (IL-6) and interleukin-18 (IL-18) levels, plasma B-type natriuretic peptide (BNP) and serum cystatin C values were determined. The primary outcome was in-hospital mortality while secondary outcome was six-month mortality.</p><p><strong>Results: </strong>Median serum and urine IL-6 levels, serum and urine IL-18 levels, as well as median concentrations of plasma BNP and serum cystatin C, were significantly increased in deceased in comparison to surviving AHF and/or ACS patients. Univariate Cox regression analysis identified serum IL-6, serum IL-18, urine IL-6, urine IL-18 as well as serum cystatin C and Acute Physiology and Chronic Health Evaluation (APACHE) II score as risk factors for mortality after an episode of AHF and/or ACS. Multivariate Cox regression analysis revealed that only serum IL-6 is the independent risk factor for mortality after acute cardiac events (HR 61.7, 95% CI 2.1-1851.0; p=0.018).</p><p><strong>Conclusion: </strong>Present study demonstrated the strong prognostic value of serum IL-6 in predicting mortality of patients with AHF and/or ACS.</p>","PeriodicalId":60467,"journal":{"name":"高校应用数学学报","volume":"32 1","pages":"252-255"},"PeriodicalIF":0.0,"publicationDate":"2016-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74431374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
高校应用数学学报Pub Date : 2016-05-01DOI: 10.4103/0970-0358.191319
Jyoshid R Balan
{"title":"Free toe pulp flap for finger pulp and volar defect reconstruction.","authors":"Jyoshid R Balan","doi":"10.4103/0970-0358.191319","DOIUrl":"10.4103/0970-0358.191319","url":null,"abstract":"<p><strong>Background: </strong>Fingertip injury requiring flap cover is very common in the modern era. The ideal cover should fulfill both functional and aesthetic improvement.</p><p><strong>Materials and methods: </strong>From June 2015 to April 2016, we performed seven free toe pulp flaps for finger defect reconstruction. All patients were males. Five flaps were done in emergency post-traumatic cases, and two were done in elective set up. The cases included reconstruction of three thumbs, one index and one ring finger in an emergency set up and two ring fingers in the elective. Thumb reconstruction was done with great toe lateral pulp and the other digits reconstructed with second toe pulp flap. Follow-up evaluation included both functional and aesthetic assessment.</p><p><strong>Results: </strong>Five flaps survived completely, one suffered partial loss, and one flap failed completely. The median follow-up period was 9 months. The median duration of surgery was 255 min (range 210 to 300 min). The median two-point discrimination was 6.5 mm (range 4-8 mm). There was the return of temperature sensation in all patients; two had cold intolerance. The Semmes-Weinstein monofilament score varied from 3.61 to 5.07 (median filament index value 4.31/pressure value of 2 g/mm<sup>2</sup>). Three patients had delayed donor site wound healing.</p><p><strong>Conclusions: </strong>The free toe pulp flap is an efficient choice for fingertip and volar finger defects reconstruction with an excellent tissue match.</p>","PeriodicalId":60467,"journal":{"name":"高校应用数学学报","volume":"19 1","pages":"178-184"},"PeriodicalIF":0.8,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74388600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}