四川大学学报(自然科学版)最新文献

四川大学学报(自然科学版) Pub Date : 2023-11-23 DOI: 10.19907/j.0490-6756.2023.066004

郑浩睿 | 王韬宇 | 薛海瑞 | 唐琳

引用次数: 0

二茂铁基吡喃酮并喹啉化合物的高效合成及其抗氧化性能二茂铁基吡喃酮并喹啉化合物的高效合成及其抗氧化性能

四川大学学报(自然科学版) Pub Date : 2022-05-19 DOI: 10.19907/j.0490-6756.2022.035001

张晓平 | 金桂勇 | 马胜涛 | 王二彬 | 赵学斌 | 陈芝飞 | 李倬 | 楚文娟 | 赵旭 | 席高磊

引用次数: 0

[Retraction Note: Association of Gene Polymorphisms in Wnt Signal Pathway with Tuberculosis in Chinese Tibetan Population.2016,47(6):920-925.] [回注:中国藏族人群Wnt信号通路基因多态性与结核病的关系。2016,47(6):920-925.]

四川大学学报(自然科学版) Pub Date : 2019-03-01 DOI: 10.13464/j.scuxbyxb.2016.06.021

Wenjing Zhou, Xuejiao Hu, Jingya Zhang, Yi Zhou, Li-juan Wu, Minjin Wang, Nian Wang, Xiao-jun Lu, B. Ying

引用次数: 0

[Endovascular Treatment of Blood Blister-like Aneurysms in Internal Carotid Artery]. 颈内动脉血泡样动脉瘤的血管内治疗

四川大学学报(自然科学版) Pub Date : 2018-08-28 DOI: 10.3760/CMA.J.ISSN.1673-4165.2018.08.008

Shouwei Xiang, Ding Xu, Chaohua Wang, Lijuan Hu, C. Zhang, Xiaodong Xie

{"title":"[Endovascular Treatment of Blood Blister-like Aneurysms in Internal Carotid Artery].","authors":"Shouwei Xiang, Ding Xu, Chaohua Wang, Lijuan Hu, C. Zhang, Xiaodong Xie","doi":"10.3760/CMA.J.ISSN.1673-4165.2018.08.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4165.2018.08.008","url":null,"abstract":"OBJECTIVES\u0000To study the feasibility and effectiveness of endovascular treatment to blood blister-like aneurysms (BBA) in internal carotid artery.\u0000\u0000\u0000METHODS\u0000Retrospective analyzed the clinical features, outcomes, and complications of 20 cases of BBA treated with endovascular intervention techniques from 2013-2015 in our center.\u0000\u0000\u0000RESULTS\u0000The patients were treated with covered stent, internal carotid artery balloon occlusion, and stents assisted coiling, respectively. One death occurred after the patient accepted covered stent treatment, another 2 death was due to vasospasm after internal carotid artery balloon occlusion, and double stents assisted coiling, respectively. The modified Rankin Scale (mRS) score when patients being discharged were 0-2 in 15 cases, and 3-4 in 2 cases. There were 17 cases with clinical follow-up from 1 to 26 months (9.3 months on average), the mRS scores were all less than 2 points. 16 cases accepted angiographic review. 14 cases had BBA totally occluded, 1 case had stable neck residue, and 1 case had incompleted occlusion and the aneurysm dwindled at follow-up.\u0000\u0000\u0000CONCLUSIONS\u0000Stent-assisted coiling is feasible and effective in the treatment of BBA in internal carotid artery.","PeriodicalId":59725,"journal":{"name":"四川大学学报(自然科学版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83444513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Prognostic determinants of adrenocortical carcinoma in adults]. 成人肾上腺皮质癌的预后决定因素。

四川大学学报(自然科学版) Pub Date : 2014-05-20 DOI: 10.1200/JCO.2014.32.15_SUPPL.E15615

Ming-feng Zhang, Chun Wang, Hui Huang, Z. Ding, Yang Liu, Hao Deng, Shuang-qing Li

{"title":"[Prognostic determinants of adrenocortical carcinoma in adults].","authors":"Ming-feng Zhang, Chun Wang, Hui Huang, Z. Ding, Yang Liu, Hao Deng, Shuang-qing Li","doi":"10.1200/JCO.2014.32.15_SUPPL.E15615","DOIUrl":"https://doi.org/10.1200/JCO.2014.32.15_SUPPL.E15615","url":null,"abstract":"OBJECTIVE\u0000To investigate the clinical features and prognostic determinants of adrenocortical carcinoma (ACC) in adult patients.\u0000\u0000\u0000METHODS\u0000All adult patients (aged > or =18 years old) who were admitted to West China Hospital, Sichuan University from 1st Jan., 2000 to 31st Jan., 2013 with a pathologically diagnosed ACC were included in this study. Data about the demographics, clinical characteristics, laboratory examinations and outcomes of those patients were extracted and analyzed.\u0000\u0000\u0000RESULTS\u0000A total of 52 cases were identified, with a median follow-up of 26 months (3-159 months). The patients had a median survival time of 29 months (1-156 months), with a 1-year, 3-year; and 5-year survival rate of 71.0%, 47.0%, and 42.7%, respectively. In the univariate analysis, aged >45 years old at diagnosis (P = 0.017), advanced stage (III-IV stage, P<0.001), incomplete resection (P = 0.011), symptomatic (P = 0.017), hypoalbuminemia (P = 0.003), and elevated lactate dehydrogenase (LDH) (P = 0.017) were associated with poor prognosis of ACC. The multivariate analysis confirmed that hypoalbuminemia Chazard ratio (HR) = 5.306; 95% confidence interval (95% CI: 1.975, 14.258; P = 0.001), female (HR = 4.020; 95% CI: 1.610, 10.038; P = 0.003), advanced stage (HR = 7.405; 95% CI: 2.561, 21.410; P < 0.001), and older age (HR = 4.628; 95% CI: 1.791, 11.959; P = 0.002) were predictors of poor prognosis of ACC.\u0000\u0000\u0000CONCLUSION\u0000Hypoalbuminemia, female, older age, and advanced stage are independent risk factors associated with poor prognosis of ACC.in adult patients.","PeriodicalId":59725,"journal":{"name":"四川大学学报(自然科学版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76198151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Glucose metabolism in elderly patients with essential hypertension and risk of cardiovascular diseases]. [老年原发性高血压患者的糖代谢与心血管疾病的风险]。

四川大学学报(自然科学版) Pub Date : 2010-03-01 DOI: 10.1097/00004872-201106001-00854

Yan Zhang, Xin-jun Zhang, Jun-qi Zhang, L. Zhong, Zhi Zeng

{"title":"[Glucose metabolism in elderly patients with essential hypertension and risk of cardiovascular diseases].","authors":"Yan Zhang, Xin-jun Zhang, Jun-qi Zhang, L. Zhong, Zhi Zeng","doi":"10.1097/00004872-201106001-00854","DOIUrl":"https://doi.org/10.1097/00004872-201106001-00854","url":null,"abstract":"OBJECTIVE\u0000To investigate the characteristics of glucose metabolism in elderly patients with essential hypertension and its association with cardiovascular diseases.\u0000\u0000\u0000METHODS\u0000One hundred and nineteen elderly patients with essential hypertension and no diagnosed diabetes mellitus were recruited. Thirty-one elderly patients with neither diagnosed diabetes mellitus nor essential hypertension served as controls. Data about the history of smoking, BMI, IRI and ISI were collected from the participants. According to oral glucose tolerance test (OGTT), the patients with essential hypertension were divided into normal glucose tolerance group (NGT), impaired glucose regulation group (IGR) and diabetes mellitus group (DM). The BMI, FPG, PPG, TG, TC, LDL, HDL, SBP, DBP, IMT, LVMI and LVEF were compared between the groups.\u0000\u0000\u0000RESULTS\u0000The patients with essential hypertension had significantly higher smoking rate and higher BMI, IRI, ISI, PPG, FIN, PIN, Cr, UA, TG and HDL than the controls (P < 0.05). IRI was correlated with BMI, SBP, DBP, TG and HDL. DM, IGR and abnormal glucose metabolism were identified in 24.4%, 38.6%, and 63% of the elderly patients with essential hypertension patients, respectively. The patients in the IGR group and DM group had significantly higher FPG, PPG, PIN, IRI, ISI, BMI, Cr, TG, HDL, LDL and SBP than those in the NGT group (P < 0.05). The incidence of plaque and LVEF in the patients with IGR and DM were higher than in the patients with normal glucose tolerance (P < 0.05).\u0000\u0000\u0000CONCLUSION\u0000Elderly patients with essential hypertension have abnormalities in glucose metabolism. OGTT should be offered to the elderly patients with essential hypertension as a measure to detect DM and prevent cardiovascular diseases.","PeriodicalId":59725,"journal":{"name":"四川大学学报(自然科学版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89595529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Immunogenicity of interleukin 12 and DNA vaccine prime-BCG boost against Mycobacterium tuberculosis]. [白细胞介素12和DNA疫苗对结核分枝杆菌的免疫原性]。

四川大学学报(自然科学版) Pub Date : 2008-07-01 DOI: 10.1016/J.IJID.2010.02.609

Lei Gao, L. Bao, Mu Hao, Le Zhang, Z. Qin

引用次数: 3

[Behavioral features of men who have sex with men]. [与男性发生性关系的男性的行为特征]。

四川大学学报(自然科学版) Pub Date : 2004-05-01 DOI: 10.2202/1948-4682.1026

Y. Lan, Y. Gu, Bin Wang, D. Zhou, Jian-xin Zhang

{"title":"[Behavioral features of men who have sex with men].","authors":"Y. Lan, Y. Gu, Bin Wang, D. Zhou, Jian-xin Zhang","doi":"10.2202/1948-4682.1026","DOIUrl":"https://doi.org/10.2202/1948-4682.1026","url":null,"abstract":"OBJECTIVE\u0000This behavioral surveillance survey in Sichuan province was aimed to gain an insight into the behavioral features related to HIV prevalence among men who have sex with men (MSM).\u0000\u0000\u0000METHODS\u0000The pilot survey was initiated in the year from September to December, 2003. Two cities, Chengdu and Nanchong, were selected as the surveillance sites. All behavioral data were collected by a special questionnaire. Convenience sampling and snowball sampling techniques were applied to recruit participants in 5 types of places where MSM appeared more often.\u0000\u0000\u0000RESULTS\u0000Most of the participants sexed only with male partners, and the most common ways of intercourse for MSM were anal sex, mouth sex and masturbation. The cases of multiple sex partners existed generally in MSM. The median partner numbers for anal sex and mouth sex were 4.4 and 4.2 respectively. There were 491 MSM (84.7%) who had sexed with male partners 6 months before, in which 68.6% of them sexed with non-commercial regular male partners, 66.2% with non-commercial non-regular male partners, and 20.4% with commercial male partners. Condom use with different male partners varied significantly. The proportions of consistent condom use with non-commercial regular, non-commercial non-regular, and commercial male partners were 15.8%, 16.3% and 32.3% respectively. 1.9% of participants reported they had had the experience of injecting drug and 18.3% of participants reported they had been tested for HIV antibody 12 months before.\u0000\u0000\u0000CONCLUSION\u0000High risk behaviors such as multiple sex partners, unprotected anal sex, commercial sex, and injecting drug use among the MSM population in the two cities were unveiled broadly.","PeriodicalId":59725,"journal":{"name":"四川大学学报(自然科学版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73408279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13