世界临床传染病学杂志(英文版)最新文献

{"title":"Monkeypox in humans: Transmission, pathophysiology, diagnosis, treatment, prevention, and all recent updates","authors":"Taral K. Parikh, Ashish M Goti, K. Yashi, Nilesh Dankhara, Sandhya Kadam, Rameshkumar Dihora, Kapil Paiwal, Narendrasinh Parmar","doi":"10.5495/wjcid.v13.i4.31","DOIUrl":"https://doi.org/10.5495/wjcid.v13.i4.31","url":null,"abstract":"The Centers for Disease Control and Prevention (CDC) is monitoring an epidemic of monkeypox infection in the United States. The outbreak is now global and more than 6900 cases have already been reported. There are 83 confirmed cases among children and adolescents, as shown in the report published on November 3, 2022, in the USA. However, monkeypox in pediatric patients is still infrequent (< 0.3% of total cases). Among cases in the United States, 16 cases were in children < 5 years, 12 in the age group 5-12 years, and 55 cases in adolescents 13-17 years old. In the adolescent age group, 89% were male. For children < 12 years of age, close physical contact with an adult household with monkeypox was the primary exposure, but for adolescents, male-to-male sexual contact was found more frequently. The CDC advised United States healthcare providers to remain vigilant for patients with a rash resembling monkeypox, even if there is no history of travel to a country with high risk. This article summarizes the history and epidemiology of monkeypox with a specific emphasis on clinical features and management in pediatric patients.","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of clinical characteristics and risk factors between elderly patients with severe and nonsevere Omicron variant infection","authors":"Xiao-Qin Liu, Guanzhu Lu, Donglin Yin, Yao-Yue Kang, Yuan-Yuan Zhou, Yu-Huan Wang, Jie Xu","doi":"10.5495/wjcid.v13.i4.37","DOIUrl":"https://doi.org/10.5495/wjcid.v13.i4.37","url":null,"abstract":"BACKGROUND Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and deaths worldwide. Elderly patients are at high risk of developing and dying from COVID-19 due to advanced age, decreased immune function, intense inflammatory response, and comorbidities. Shanghai has experienced a wave of infection with Omicron, a new variant of SARS-CoV-2, since March 2022. There is a pressing need to identify clinical features and risk factors for disease progression among elderly patients with Omicron infection to provide solid evidence for clinical policy-makers, public health officials, researchers, and the general public. AIM To investigate clinical characteristic differences and risk factors between elderly patients with severe and nonsevere Omicron SARS-CoV-2 variant infection. METHODS A total of 328 elderly patients with COVID-19 admitted to the Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from April 2022 to June 2022 were enrolled and divided into a severe group (82 patients) and a nonsevere group (246 patients) according to the diagnosis and treatment protocol of COVID-19 (version 7). The clinical data and laboratory results of both groups were collected and compared. A chi-square test, t test, Mann-Whitney U test, hierarchical log-rank test, univariate and multivariate logistic regression, and hierarchical analyses were used to determine significant differences. RESULTS The severe group was older (84 vs 74 years, P < 0.001), included more males (57.3% vs 43.9%, P = 0.037), had a lower vaccination rate (P < 0.001), and had a higher proportion of comorbidities, including chronic respiratory disease (P = 0.001), cerebral infarction (P < 0.001), chronic kidney disease (P = 0.002), and neurodegenerative disease (P < 0.001), than the nonsevere group. In addition, severe disease patients had a higher inflammatory index (P < 0.001), greater need for symptomatic treatment (P < 0.001), longer hospital stay (P = 0.011), extended viral shedding time (P = 0.014), and higher mortality than nonsevere disease patients (P < 0.001). No difference was observed in the application of Paxlovid in the severe and nonsevere groups (P = 0.817). Oxygen saturation, cerebral infarction, and D-dimer were predictive factors for developing severe disease in patients with COVID-19, with D-dimer having an excellent role (area under the curve: 90.1%, 95%CI: 86.1-94.0%). In addition, D-dimer was a risk factor for developing severe COVID-19 according to multivariate stratified analysis. CONCLUSION The clinical course of severe COVID-19 is complex, with a higher need for symptomatic treatment. D-dimer is a suitable biomarker for identifying patients at risk for developing severe COVID-19.","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brucellosis, a diagnostic dilemma, presenting atypically in a child with terminal ileitis: A case report","authors":"Kokila Banerjee, Amitava Pahari, Subhendu Roy","doi":"10.5495/wjcid.v13.i3.24","DOIUrl":"https://doi.org/10.5495/wjcid.v13.i3.24","url":null,"abstract":"","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135667737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging leishmaniasis in southern Himalayas: A mini-review","authors":"Ashwani Sharma, Santosh Kumar, P. Panda, Sweety Yadav, D. Kalita","doi":"10.5495/wjcid.v13.i2.11","DOIUrl":"https://doi.org/10.5495/wjcid.v13.i2.11","url":null,"abstract":"","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41628320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional models of antigens with serodiagnostic potential for leprosy: An in silico study","authors":"Bianca Luiza Melo de Assis, Rafaela Viana Vieira, Ian Theodoro Rudenco Gomes Palma, Matheus Bertolini Coutinho, J. D. de Moura, Gabrielle C Peiter, K. N. Teixeira","doi":"10.5495/wjcid.v13.i1.1","DOIUrl":"https://doi.org/10.5495/wjcid.v13.i1.1","url":null,"abstract":"","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47321599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Steps taken to fight the COVID-19 pandemic at the grassroots level of rural India: Experience of a community physician","authors":"Ankit Chandra","doi":"10.5495/wjcid.v12.i3.76","DOIUrl":"https://doi.org/10.5495/wjcid.v12.i3.76","url":null,"abstract":"","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46270388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical significance of anti-nucleocapsid-IgG sero-positivity in SARS-CoV-2 infection in hospitalized patients in North Dakota","authors":"Bakir Dzananovic, M. Williamson, C. Nwaigwe, C. Routray","doi":"10.5495/wjcid.v12.i2.50","DOIUrl":"https://doi.org/10.5495/wjcid.v12.i2.50","url":null,"abstract":"This paper presents a case study concerning several epidemiologic-clinical parameters when they are taken hospitalized with severe COVID-19 illness. The authors provide statistical analysis of a certain group of patients tested for COVID-19 who were admitted to a hospital in North Dakota. The authors conclude that the admission rate to the ICU and the use of BiPAP, HFNC and VENT support were not significantly distinct across IgG status. However, an important parameter related to monitoring the patients’ condition - the length of stay - when assessed by IgG status was found to be significant. In overall, the paper is well-written and flows logically. Technically, the authors apply regression models to better fit their data, hence improving the quality of the results and their analysis. Although the discussion and data analysis have been performed adequately, I believe that a correlation study involving the examined variables would bring interesting insights and a richer discussion of the results.","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46389877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental diagnosis of intestinal spirochetosis in a patient with chronic hepatitis B: A case report","authors":"S. Novotny, J. Mizrahi, E. Yee, Michael J. Clores","doi":"10.5495/wjcid.v12.i2.69","DOIUrl":"https://doi.org/10.5495/wjcid.v12.i2.69","url":null,"abstract":"","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42742644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pericarditis following COVID-19 vaccination: Two case reports","authors":"Justyna Fydrych, Amanda Hughes, S. Abuhasna, Endale T. Mekonen","doi":"10.5495/wjcid.v12.i1.33","DOIUrl":"https://doi.org/10.5495/wjcid.v12.i1.33","url":null,"abstract":"","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44805060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mutations of the brpR and brpS genes affect biofilm formation in Staphylococcus aureus","authors":"A. Zank, Lillian Schulte, Xavier Brandon, L. Carstensen, Amy Wescott, W. Schwan","doi":"10.5495/wjcid.v12.i1.20","DOIUrl":"https://doi.org/10.5495/wjcid.v12.i1.20","url":null,"abstract":"","PeriodicalId":56483,"journal":{"name":"世界临床传染病学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43679599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}