FigsharePub Date : 2016-02-27DOI: 10.1021/jo702401t.s002
Zhi Wang (193655), Yong-Tao Cui (2447953), Zhao-Bing Xu (2447950), Jin Qu (833943)
{"title":"Hot Water-Promoted Ring-Opening of Epoxides and Aziridines bynWater and Other Nucleopliles","authors":"Zhi Wang (193655), Yong-Tao Cui (2447953), Zhao-Bing Xu (2447950), Jin Qu (833943)","doi":"10.1021/jo702401t.s002","DOIUrl":"https://doi.org/10.1021/jo702401t.s002","url":null,"abstract":"Effective hydrolysis of epoxides and aziridines was conducted by heating them in water at 60 or 100 °C.nOther types of nucleophile such as amines, sodium azide, and thiophenol could also efficiently opennepoxides and aziridines in hot water. It was proposed that hot water acted as a modest acid catalyst,nreactant, and solvent in the hydrolysis reactions.","PeriodicalId":521889,"journal":{"name":"Figshare","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147887438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}