Cardiovascular sciencePub Date : 2025-01-01Epub Date: 2025-06-27DOI: 10.70322/cvs.2025.10007
Robert Chait, Fergie Ramos Tuarez, Jesus E Pino, Dipan Uppal, David Snipelisky
{"title":"Non-Invasive Evaluation by the HEMOTAG<sup>™</sup> Recording Device to Tailor Treatment of Acutely Decompensated Heart Failure.","authors":"Robert Chait, Fergie Ramos Tuarez, Jesus E Pino, Dipan Uppal, David Snipelisky","doi":"10.70322/cvs.2025.10007","DOIUrl":"10.70322/cvs.2025.10007","url":null,"abstract":"<p><p>This study evaluated the clinical utility of the HEMOTAG<sup>™</sup> recording device-A non-invasive, wearable system that measures cardiac time intervals (CTIs)-in managing patients with acutely decompensated heart failure (ADHF). The prospective, single-center study enrolled 105 patients, including those hospitalized with ADHF and a control group with non-HF-related conditions. Daily measurements of isovolumetric contraction time (IVCT), a key CTI marker, were collected using the HEMOTAG device and compared with NT-proBNP levels obtained on admission and day 3. Among ADHF patients, IVCT decreased in parallel with NT-proBNP levels, indicating volume status improvement with therapy. In contrast, the control group showed no significant change in IVCT or NT-proBNP. An IVCT ≥ 40 ms demonstrated strong sensitivity and specificity to detect ADHF (NT-proBNP ≥ 1800 pg/mL). These findings suggest that IVCT trends measured by HEMOTAG correlate with short-term treatment response in ADHF and could offer a non-invasive method to guide heart failure management. The technology demonstrated feasibility, safety, and clinical relevance, supporting its potential role in future remote management strategies.</p>","PeriodicalId":521193,"journal":{"name":"Cardiovascular science","volume":"2 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12781972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145954947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}