Advances in cancer education and quality improvement最新文献

{"title":"Clinical Medical Emergency Team Training Simulation (CMETTS): An Interprofessional Simulation for Medical Students and Nursing Residents.","authors":"Allan John R Barcena, Marvin R Bernardino, Dominic Karl M Bolinas, Kitz Paul D Marco, Toni Edwards, Shelita Kimble, James Cavalier, Marites P Melancon, Jillian R Gunther","doi":"10.52519/aceqi.26.2.1.a11","DOIUrl":"10.52519/aceqi.26.2.1.a11","url":null,"abstract":"<p><p>Effective teamwork and communication are critical during medical emergencies, particularly in oncology, yet health care professionals are often trained separately, creating challenges for interprofessional collaboration. Evidence-based frameworks like Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS) offer structured tools to optimize team performance. This study describes a simulation-based program, the Clinical Medical Emergency Team Training Simulation (CMETTS), designed to instill foundational teamwork skills in early-stage learners. First-year medical students and newly graduated nursing residents participated in an interprofessional simulation involving medical emergency scenarios followed by structured debriefing sessions guided by TeamSTEPPS principles. We evaluated the program's effectiveness using pre- and postsimulation surveys assessing self-reported knowledge, confidence, and overall satisfaction with the training. A total of 110 trainees (21 medical students, 89 nursing residents) completed the evaluation. The simulation was exceptionally well-received, with more than 95% of participants from both groups rating the experience positively and agreeing they would recommend it to colleagues. After the simulation, there were statistically significant increases in both self-reported knowledge (<i>P</i> < .001) and confidence (<i>P</i> < .001) for all participants. While nursing residents demonstrated higher baseline scores, both groups showed significant individual learning gains, indicating the program's value for learners at different professional stages. The CMETTS program is an effective educational intervention for introducing foundational teamwork and communication skills to early-stage medical and nursing trainees. By providing a safe, realistic environment for practicing interprofessional collaboration, this simulation helps prepare future health care professionals for the demands of team-based care and ultimately aims to enhance patient safety.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147871243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons Learned for Improving Trainee Engagement and Utilization of Education and Training Materials for Cancer Research.","authors":"Katerina M Santiago, Tania Galindo, Michaela A Dinan","doi":"10.52519/aceqi.26.2.1.a10","DOIUrl":"10.52519/aceqi.26.2.1.a10","url":null,"abstract":"<p><strong>Background: </strong>A core component of the National Cancer Institute Cancer (NCI) Cancer Center Support Grant requires cancer centers to coordinate research career enhancement and related activities. The Yale Cancer Center, an NCI-designated comprehensive cancer center, established the Cancer Research Training and Education Coordination (CRTEC) component in 2016. In response to the needs of trainees, CRTEC has developed several initiatives that we have identified and described here as best practices to engage and support trainees.</p><p><strong>Methods: </strong>We had 2 aims to improve engagement: 1) increasing our visibility and trainee awareness of CRTEC and nurturing bidirectional communication and 2) offering meaningful events for trainees pursuing a career in cancer research. To accomplish these goals, we created a CRTEC logo, email account, centralized trainee database, monthly announcement newsletter, centralized repository of trainings, website, and LinkedIn profile. A networking event series called \"Brewing Connections\" and a cancer center trainee membership program were also developed and implemented.</p><p><strong>Results: </strong>The CRTEC email has sent approximately 932 emails. Six of these pertained to the Brewing Connections series, which has had a total of 61 trainees attend. The CRTEC LinkedIn page has amassed 91 followers, and a single post has reached 2535 impressions. A total of 14 trainees have utilized the toolkit.</p><p><strong>Conclusion: </strong>These initiatives demonstrate successful practices for engaging with trainees at cancer centers.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148020542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Imaging to Impact: A Multi-Disciplinary T32 Program Framework and Initial Insights for Training in Image-Guided Cancer Therapy [Advance Publication].","authors":"Kari J Brewer Savannah, Stephen Y Lai, Clifton D Fuller, Kristy K Brock","doi":"10.52519/aceqi.25.1.2.a1","DOIUrl":"10.52519/aceqi.25.1.2.a1","url":null,"abstract":"<p><p>As multi-disciplinary image-guided assessment and therapies become increasingly important for precision oncology, the need for comprehensive training opportunities that effectively prepare the next generation of clinician-scientists and scientists is evident. We present an innovative, evidence-based research training framework that integrates the following critical features: 1) intentional and personalized mentoring and career development, 2) immersive research in image-guided cancer therapy, 3) strategic mentored clinical exposure, 4) structured didactic learning and professional development opportunities, and 5) mentored grant writing. Designed to foster scientific rigor, translational thinking, and multi-disciplinary collaboration, the Image-Guided Cancer Therapy T32 Training Program (IGCT-T32) aims to prepare postdoctoral fellows from MD, MD/PhD, and PhD backgrounds for successful careers in image-guided cancer therapy research. Additionally, we describe programmatic enhancements driven by trainee feedback, including improved flexibility and customization of training plans, and the establishment of an open-access educational repository, enabling on-demand access to didactic learning materials. Through this repository, IGCT-T32 can broadly disseminate educational resources, allowing learners and educators beyond the program to integrate these critical resources into their own training in image-guided cancer therapy. Preliminary data from the initial program trainee cohort (n=3) indicates strong research productivity, with trainees averaging 3.2 presentations and 1.8 invited talks per year in training. When compared with non-T32 peers, IGCT-T32 trainees published substantially more first and co-authored peer-reviewed manuscripts, averaging 1.6 vs. 0.36 first authored manuscripts per trainee for each year in training and 6.0 vs. 0.26 co-authored manuscripts per trainee for each year in training, respectively. IGCT-T32 fellows published 77.1% of their peer-reviewed manuscripts in top quartile journals in their fields compared with only 55.6% of manuscripts from their non-T32 peers. Further, IGCT-T32 trainees were ~10% more likely to utilize preprints (such MedRxiv) for early dissemination of research. Together, these data provide promising early indicators of the effectiveness of the IGCT-T32 training program and its design. We offer here a descriptive framework for the development of training curricula in image-guided cancer therapy that could be adapted for other sites and stakeholders. While preliminary insights into program effectiveness are promising, continued evaluation and longitudinal data are needed with additional trainees to fully access its impact and generalizability.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"1 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12646052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing an Electronic Patient-Reported Outcomes Information Infrastructure Supported by the RE-AIM Implementation Framework.","authors":"Amy C Moreno, Angela Peek, Toshiko S Stein, Kevin R Shook, Sara M Ali, Laia Humbert-Vidan, Aileen Chen, Miriam Lango, Anna Lee, Michael Spiotto, William H Morrison, Adam S Garden, Jack Phan, Steven J Frank, Katherine Hutcheson, David I Rosenthal, Clifton D Fuller, G Brandon Gunn","doi":"10.52519/aceqi.25.1.2.a6","DOIUrl":"10.52519/aceqi.25.1.2.a6","url":null,"abstract":"<p><strong>Objective: </strong>Patient-reported outcomes (PROs) contain valuable information that can be leveraged by providers to perform timely interventions and improve quality of life and survival. However, the implementation of electronic PROs (ePROs) remains a challenge from technical and evaluation perspectives. Our objective was to construct a robust electronic health record (EHR)-integrated ePRO information infrastructure founded on RE-AIM (reach-effectiveness-adoption-implementation-maintenance) principles.</p><p><strong>Materials and methods: </strong>We used Epic Systems as our EHR platform to build the MD Anderson Symptom Index Head and Neck Module (MDASI-HN) for release to all patients undergoing evaluation and/or treatment in our HN Radiation Oncology clinics. RE-AIM metrics were established and used to design patient, provider, and implementing facilitator information tools.</p><p><strong>Results: </strong>From January 2021 to July 2024, our ePRO program has collected 13,156 <b>patient-submitted</b> ePROs on 3,497 unique HN patients, with a 12-month sustained ePRO compliance rate of 82%. We also propose a dynamic 2-cycle implementation model. This model can be used to continuously (re)define, build, and adapt ePRO information tools for patients, providers, and program facilitators.</p><p><strong>Discussion: </strong>Our ePRO framework has several benefits, including integrated clinical data for enhanced decision-making, potential scalability, and use of a common EHR system. Formative (ie, mid-phase) evaluations were essential to our program, allowing for timely optimization of ePRO compliance, ePRO usage by clinical staff, and secondary use of high-quality ePRO data.</p><p><strong>Conclusion: </strong>In this article, we provide a valuable roadmap toward developing a comprehensive, EHR-based ePRO information infrastructure simultaneously optimized for clinical utility, informatics operations, and implementation evaluation founded on RE-AIM principles.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"1 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12854710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-Person and Virtual Adaptation of an Interprofessional Palliative Care Communications Skills Training Course for Pediatric Oncology Clinicians.","authors":"Karen M Moody, Clark R Andersen, Robert M Arnold, Julie Bradley, Allie Carter, Lauren Draper, Timothy P Garrington, Jonathan Gill, Douglas Harrison, Masanori Hayashi, Amy Heaton, Cynthia Holladay, Alex H Lion, Alakh Rajan, Beatriz Rozo, Daniel V Runco, Shermini Saini, Laura Salvador, Kathryn S Sutton, Verna L Hendricks-Ferguson","doi":"10.52519/aceqi.25.1.1.a2","DOIUrl":"10.52519/aceqi.25.1.1.a2","url":null,"abstract":"<p><strong>Introduction: </strong>Empathic communication is crucial for clinicians when discussing palliative and end-of-life (PC/EOL) care with parents of children with cancer. Unfortunately, many parents report inadequate communication at these distressing times. This study evaluates the communication skills training (CST) clinicians received to deliver a PC/EOL communication intervention as part of a multi-site randomized-controlled trial (RCT). Training was provided using an in-person format and then adapted to a virtual platform to accommodate remote learners.</p><p><strong>Methods: </strong>Clinicians were trained in dyads (one physician and one nurse [RN] or advanced practice provider [APP]) over 3 days (in-person or virtually). Four pediatric oncology cases were developed and each incorporated three timepoints: diagnosis, disease progression, and end-of life. Training was adapted from VitalTalk^™ and included didactic instruction, videos, visual aids, and role play. Participants completed a confidential, post-training survey. A self-reported quality assurance checklist measured fidelity to the intervention during the RCT.</p><p><strong>Results: </strong>Thirty clinicians completed training; 26 completed post-training surveys including 46.1% physicians, 30.8% RNs and 23.1% APPs. Most were female (65.4%); white (80.8%), and 40-50 years old (53.9%). Nine (34.6%) trained in-person; the rest trained virtually. Ninety-two percent reported the course was valuable/very valuable for developing PC/EOL communication skills and 96% learned something new. Dyads trained virtually had similar fidelity to those trained in-person (95% and 90% respectively) when delivering the intervention to parents.</p><p><strong>Discussion: </strong>This PC/EOL CST, implemented in-person and virtually, was valuable for improving pediatric oncology clinicians' communication skills and was translated effectively into practice.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12629249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145567066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Virtual Wellness Program to Enhance Well-being for Pediatric Oncology Staff during the COVID-19 Pandemic.","authors":"Karen M Moody, Maria Chang Swartz, Zachary Gresham, Martha Askins, Laura Cahalan, Christine Geistkemper, Amy Heaton, Ruitao Lin, Melissa Melo, Alakh Rajan, Madeline Smith, Priti Tewari, Keyana Williams, Cheng-Han Yang, Rhonda Robert","doi":"10.52519/ACEQI.25.1.1.a18","DOIUrl":"10.52519/ACEQI.25.1.1.a18","url":null,"abstract":"<p><p>In response to the COVID-19 global health crisis and mandated social isolation, Pediatric leadership at MD Anderson Children's Cancer Hospital was concerned for the psychological impact on its workforce and encouraged wellness programming. A grassroots wellness taskforce was assembled for the Division of Pediatrics. The task force's primary mission was to promote the well-being of clinicians and non-clinical staff members through a broadly accessible, sustainable, and effective virtual wellness program. Guided by the Stanford Model for Professional Fulfillment, a virtual program entitled, \"Weekly Wellness Webex\" for Pediatrics staff was launched. Weekly Wellness Webex is a 1-hour live-streamed program with varied thematic content promoting personal resilience through healthy behaviors and self-care such as mindfulness, nutrition and exercise, and a culture of wellness through games, group art projects, and activities that highlighted diversity and inclusion. The program was evaluated and modified based on data collected from a confidential electronic evaluation program sent to the staff at three separate timepoints over 18 months. We performed descriptive statistical analyses and used manual coding to analyze the free-text qualitative data received from the evaluations. Sixty-nine program sessions and 3 participant evaluations were conducted between March 2020 and September 2021. Of 300 total staff, 114 participated in the wellness program representing 38% of the Division of Pediatrics. In addition, 125 (41.6%) completed a survey. Most participants found the program helpful (84% on the first evaluation and 100% on the 2nd and 3rd evaluations) and 69.4% (95% CI 62.9-75.9%) experienced decreased COVID-19-related distress after attending the program. The mean decrease in distress after participation in the wellness program was 1.67 (SD 2.2) on a 10-point scale. On the quantitative and qualitative analysis, improved personal well-being and increased social connections emerged as the main program benefits. This virtual wellness program successfully decreased COVID-19 related distress and was perceived as helpful to pediatric oncology healthcare staff. Participants of the program endorsed increased social connectivity, improved well-being, and decreased distress. This program was successfully implemented during the pandemic and has been sustained.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Fellowship Training on Peer-Reviewed Publication Productivity in Academic Anesthesiologists as Evaluated by the h-Index.","authors":"Acsa M Zavala, Jagtar Singh Heir, Juan P Cata, Lei Feng, Jose M Soliz","doi":"10.52519/aceqi.25.1.1.a8","DOIUrl":"10.52519/aceqi.25.1.1.a8","url":null,"abstract":"<p><strong>Background: </strong>The effect of anesthesiology fellowships on scholarly contributions has been minimally studied. In this study we analyzed differences in h-index between fellowship-trained and non-fellowship-trained anesthesiologists, as well as by type of fellowship, academic rank, and years in practice.</p><p><strong>Methods: </strong>All anesthesiologists on staff between September 1, 2021, and August 31, 2022, were included in this study. The variables collected were fellowship training status, h-index, total number of publications, years in practice, academic rank, and years at the institution. For analysis, the anesthesiologists were divided into 2 groups: those with fellowship training and those without.</p><p><strong>Results: </strong>Among 78 anesthesiologists, 40 were not fellowship-trained and 38 were, with 10 types of anesthesiology fellowships identified. The h-index and number of publications did not differ between fellowship-trained and non-fellowship-trained anesthesiologists, and the number of publications per years in practice did not differ by fellowship type. The number of publications per years in practice was higher in the fellowship-trained group than in the non-fellowship-trained group (1.2 ± 1.1 vs. 0.71 ± 0.6; P = .04), as was the number of publications per years in practice at our institution (1.5 ± 1.1 compared with 0.9 ± 0.9; P = .0093).</p><p><strong>Conclusion: </strong>Fellowship training among academic anesthesiologists was not associated with a difference in h-index. However, fellowship training was associated with a higher number of publications per years in practice. Further research could elucidate the usefulness of h-index to support career development and contributions of anesthesiologists in academia.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent Improvement in Opioid Perceptions and Prescribing for Cancer Surgery: 5-Year Follow-Up.","authors":"Brittany C Fields, Timothy E Newhook, Heather A Lillemoe, Jessica E Maxwell, Jose M Soliz, Keyuri U Popat, Christina L Roland, Jean-Nicolas Vauthey, Matthew H G Katz, Ching-Wei D Tzeng","doi":"10.52519/aceqi.25.1.1.a15","DOIUrl":"10.52519/aceqi.25.1.1.a15","url":null,"abstract":"<p><strong>Background and objectives: </strong>We previously reported that implementation of a department-wide opioid education program led to post-education improvements in opioid perceptions and prescription recommendations, with one-month and one-year retention. With ongoing programmatic and quality improvement efforts, we sought to re-evaluate the retention of these improvements five years after initial efforts.</p><p><strong>Methods: </strong>Attending surgeons, clinical fellows, and advanced practice providers were surveyed five years after implementation of a comprehensive, departmental opioid reduction framework in August 2018. This framework initially consisted of dedicated opioid education sessions and retrospective assessment of prescribing practices, and subsequently expanded over time to include prospective quality improvement and implementation studies, as well as integration of opioid stewardship measures into usual clinical care. Providers' perceptions of expected pain scores, opioid requirements, and ideal prescribing habits were assessed with the same survey administered at 1-month (2018) and 1-year post-initial education (2019).</p><p><strong>Results: </strong>Eighty-seven of 162 (53.7%) providers responded to the follow-up survey. More providers expressed strong agreement with the statement, \"After an inpatient procedure, a patient who has not required opioids for 24 hours before discharge should not receive a discharge opioid prescription.\" Significant decreases in the number of opioid pills providers would prescribe at discharge for five sample operations were also observed between 2018-2023. Stepwise decreases in opioid volume prescribed in both inpatient and outpatient settings were reported since the initial 2018 education sessions.</p><p><strong>Conclusions: </strong>Dedicated department-wide opioid education, ongoing quality improvement and prospective evaluation, and integration of opioid stewardship into clinical practice were associated with sustained improvement over five years in perceptions of postoperative pain management and decreased discharge opioid prescription recommendations.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Randomized Clinical Trial Protocol.","authors":"Brittany C Fields, Timothy E Newhook, Heather A Lillemoe, Wei Qiao, Jose A Karam, Surena F Matin, Larissa A Meyer, Ching-Wei D Tzeng","doi":"10.52519/aceqi.25.1.1.a19","DOIUrl":"10.52519/aceqi.25.1.1.a19","url":null,"abstract":"<p><strong>Background: </strong>Surgeons provide up to 10% of total opioid prescriptions across all specialties, and more than one-third of surgeon-prescribed medications are opioids. Patient-reported opioid consumption and risk of persistent opioid use beyond the postoperative recovery period correlate with the initial opioid quantity prescribed at discharge. Interventions to reduce postoperative opioid prescribing have demonstrated no adverse effects on pain control or increased need for prescription refill; however, in the absence of standardized prescription protocols, opioid prescribing practices vary widely.</p><p><strong>Objective: </strong>The study objective is to identify the opioid prescribing model that provides the lowest oral morphine equivalents (OME) volume prescribed at discharge and OME consumed in the 14 days after discharge, with no adverse effect on refills and patient quality of life or satisfaction.</p><p><strong>Methods and analysis: </strong>This is a pragmatic single-center, multispecialty, double-arm phase II randomized clinical trial of two discharge opioid prescribing models. All adult (≥18 years) patients who undergo any one of five open abdominal oncologic operations (pancreatectomy, hepatectomy, retroperitoneal sarcoma resection, nephrectomy, or cytoreductive surgery for ovarian cancer) with curative intent and have a planned postoperative inpatient stay of at least 48 hours will be eligible. Patients will be stratified by their managing clinical service and randomized to receive a discharge opioid prescription based on either the 5x-multiplier algorithm or the 3-tier model. The co-primary outcomes are initial discharge OME volume and OME consumption in the 14 days after hospital discharge. Secondary outcomes include rates of patients with zero OME at discharge; rates of refill requests and completions, number of unused or leftover pills, persistent opioid use, and patient-reported quality-of-life metrics at various follow-up times; patient, prescriber, and oncologic factors predictive of persistent opioid use; and patient satisfaction. Each co-primary endpoint will be analyzed using two-sample t-test to compare means and linear regression models to assess differences between the two arms.</p><p><strong>Ethics and dissemination: </strong>This study was approved by the Institutional Review Board of The University of Texas MD Anderson Cancer Center (2023-0818). The study will evaluate the difference in initial discharge OME volume and in 14-day post-discharge OME consumption between two discharge opioid prescribing models. Upon completion of the data collection and analyses, a manuscript describing the study results will be submitted to a peer-reviewed journal for publication and dissemination. Trial Registration Number: NCT06232577.</p>","PeriodicalId":520864,"journal":{"name":"Advances in cancer education and quality improvement","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12201974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}