NPJ acoustics最新文献

Ultrasound modulates microglial activity and reduces neuroinflammation in a parameter-dependent manner. 超声调节小胶质细胞活动，减少神经炎症参数依赖的方式。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-05-06 DOI: 10.1038/s44384-026-00047-8

Sarina Grewal, Francesco Iacoponi, Lok Yin Nicholas Chan, Valeria Dosso, William Lim Kee Chang, Vanessa Drevenakova, Albert Ugwudike, Leonardo Ricotti, Paul M Matthews, Andrea Cafarelli, Sophie V Morse

{"title":"Ultrasound modulates microglial activity and reduces neuroinflammation in a parameter-dependent manner.","authors":"Sarina Grewal, Francesco Iacoponi, Lok Yin Nicholas Chan, Valeria Dosso, William Lim Kee Chang, Vanessa Drevenakova, Albert Ugwudike, Leonardo Ricotti, Paul M Matthews, Andrea Cafarelli, Sophie V Morse","doi":"10.1038/s44384-026-00047-8","DOIUrl":"10.1038/s44384-026-00047-8","url":null,"abstract":"Neuroinflammation contributes to the progression of many neurological diseases. Here, we explore whether ultrasound can reduce microglia-mediated inflammation in vitro and in vivo. We tested a broad range of ultrasound parameters in a BV2 microglial cell line, treated with lipopolysaccharide (LPS) to induce an inflammatory response. We found that specific combinations of centre frequency, acoustic pressure and treatment duration can significantly lower the levels of pro-inflammatory cytokines, including tumor necrosis factor (TNF)-α, interleukin (IL)-1β and IL-6. These effects lasted up to 72 h and were associated with the downregulation of the nuclear factor κB (NF-κB), suggesting a mechanistic link between ultrasound and inflammation. Further investigation in vivo, in LPS-treated mice, revealed a reduction in TNF-α expression in the hippocampus following ultrasound. Overall, our findings showcase the potential of ultrasound as a non-invasive therapeutic strategy to reduce neuroinflammation and restore brain homeostasis.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13149327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147871264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcranial ultrasound stimulation of the right globus pallidus interna in schizophrenia: A randomized, sham-controlled pilot study. 经颅超声刺激精神分裂症患者的右侧内苍白球：一项随机、假对照的初步研究。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-10-20 DOI: 10.1038/s44384-026-00076-3

Wei Qi, Alon Gilad, Michele Santacatterina, Spencer Brinker, Gillian Capichioni, Fumika Ando, Shy Shoham, Donald C Goff

{"title":"Transcranial ultrasound stimulation of the right globus pallidus interna in schizophrenia: A randomized, sham-controlled pilot study.","authors":"Wei Qi, Alon Gilad, Michele Santacatterina, Spencer Brinker, Gillian Capichioni, Fumika Ando, Shy Shoham, Donald C Goff","doi":"10.1038/s44384-026-00076-3","DOIUrl":"10.1038/s44384-026-00076-3","url":null,"abstract":"Functional abnormalities of the globus pallidus interna (GPi) are linked to psychosis severity and treatment response in schizophrenia. Transcranial ultrasound stimulation (TUS) is a noninvasive method for precisely targeting deep brain structures. The effects of GPi-targeted TUS on psychosis had not been examined. We conducted a random-order, sham-controlled, crossover pilot study assessing safety, tolerability, and preliminary efficacy of right GPi TUS for psychotic symptoms. Ten outpatients (mean age 37.5; 50% female) with schizophrenia or schizoaffective disorder and persistent psychosis received one TUS and one sham session, one week apart. TUS was MRI-guided, targeting right GPi with a 350 kHz transducer (100 Hz pulse repetition frequency, 5% duty cycle, in situ I spta 400 mW/cm²). Outcomes-delusion experience sampling assessment (DESA) and auditory hallucinations rating scale (AHRS)-were measured before, during, and immediately, 1 h, 1, and 7 days after stimulation. DESA scores decreased significantly more after TUS than sham (p = 0.002, Cohen's d = 0.68); AHRS and cognition changes were not significant. Mild transient adverse effects occurred in both conditions; none were serious. GPi-targeted TUS was safe, well-tolerated, and associated with a preliminary reduction in delusional severity, warranting further study in larger, randomized trials. ClinicalTrials.gov: NCT05643196, registered 21 November 2022.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"39"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13683035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149241088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flexible ultrasound array for subcortical brain stimulation in humans: a simulation study. 用于人脑皮层下脑刺激的柔性超声阵列：模拟研究。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-03-30 DOI: 10.1038/s44384-026-00046-9

Haoming Huo, Anthony DiSpirito, Nanchao Wang, Chenhang Li, Sunho Moon, Chaorui Qiu, Kaiping Yin, Huaiyu Wu, Bin Sun, Roarke Horstmeyer, Wuwei Feng, Xiaoning Jiang, Xiaoyue Ni, Junjie Yao

{"title":"Flexible ultrasound array for subcortical brain stimulation in humans: a simulation study.","authors":"Haoming Huo, Anthony DiSpirito, Nanchao Wang, Chenhang Li, Sunho Moon, Chaorui Qiu, Kaiping Yin, Huaiyu Wu, Bin Sun, Roarke Horstmeyer, Wuwei Feng, Xiaoning Jiang, Xiaoyue Ni, Junjie Yao","doi":"10.1038/s44384-026-00046-9","DOIUrl":"10.1038/s44384-026-00046-9","url":null,"abstract":"Transcranial focused ultrasound (tFUS) is a non-invasive neuromodulatory tool that holds promise for various neuropsychiatric disorders. While it offers several distinct advantages, it also faces notable technical challenges. The irregular shape and inhomogeneous acoustic properties of the human skull impede efficient acoustic energy transmission through the skull. So far, clinical semi-spherical (hemispherical) arrays still suffer from strong wave reflection and refraction at the skull interface, especially with steering. We propose a flexible ultrasound array that conforms to individual skull shapes and can be optimized to target vertex-accessible subcortical regions. The impact of flexible array configuration was investigated by comparing the flexible array with a semi-spherical array commonly used in the clinical setting. Numerical results show that the random-patterned flexible array reduces the z-axis -6 dB full width at half maximum (FWHM) by 29.4% and enhances the focal peak pressure by 44.4% when compared to the semi-spherical array without steering. In addition, it achieves a wide steering range over a 30 × 20 mm2 region while maintaining the focusing performance. We expect that our proposed tFUS stimulation with a flexible array may provide a theoretical framework for improving the therapeutic efficiency for various neuropsychiatric conditions.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13035476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GCaMP fiber photometry reveals mechanistic insights into focused ultrasound neuromodulation in acute seizures. GCaMP纤维光度法揭示了急性癫痫发作中聚焦超声神经调节的机制。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-09-02 DOI: 10.1038/s44384-026-00057-6

Chen-Syuan Huang, Yi-Chun Yeh, Po-Chun Chu, Yi-Tse Hsiao, Hsiang-Yu Yu, Robert S Fisher, Hao-Li Liu

{"title":"GCaMP fiber photometry reveals mechanistic insights into focused ultrasound neuromodulation in acute seizures.","authors":"Chen-Syuan Huang, Yi-Chun Yeh, Po-Chun Chu, Yi-Tse Hsiao, Hsiang-Yu Yu, Robert S Fisher, Hao-Li Liu","doi":"10.1038/s44384-026-00057-6","DOIUrl":"10.1038/s44384-026-00057-6","url":null,"abstract":"Generalized seizures represent a major clinical challenge in epilepsy, often resistant to pharmacological treatment and associated with significant morbidity. While low-intensity focused ultrasound (FUS) has emerged as a promising noninvasive neuromodulation strategy to suppress epileptiform activity, the underlying calcium mechanism remains poorly understood. This study, utilizing simultaneous hippocampal GCaMP fiber photometry and electrocorticography (ECoG) in acute pentylenetetrazol-induced seizure mouse models, investigated whether FUS stimulation could modulate intracellular calcium dynamics and network excitability. FUS was applied to the hippocampus with a mechanical index of 0.2, a duty cycle of 7.5%, and a total duration of 10 min. Our findings demonstrated a strong correlation between epileptic calcium transients and ECoG spikes, and FUS significantly attenuated both modalities for up to 40 min. Immunofluorescence analyses in the dentate gyrus revealed decreased c-Fos expression co-localized with both NMDAR2B and GAD65/67 after FUS treatment, indicating an overall reduction in both excitatory and inhibitory synaptic transmission. These results suggest that low-intensity FUS exerts calcium-dependent anti-seizure effects by modulating the excitatory-inhibitory balance. By providing real-time insights into neural network excitability, GCaMP fiber photometry complements traditional electrophysiology and serves as a potent mechanistic surrogate for assessing therapeutic efficacy, potentially guiding future closed-loop neuromodulation strategies.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"35"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13538028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148889985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the relevance of facesheet orifice geometry to acoustic liner impedance. 论面板孔板几何形状与声衬板阻抗的相关性。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-02-17 DOI: 10.1038/s44384-026-00044-x

Francesco Avallone, Amr Khedr, Angelo Paduano, Francesco Scarano, Lucas Meirelles, Julio Cordioli

{"title":"On the relevance of facesheet orifice geometry to acoustic liner impedance.","authors":"Francesco Avallone, Amr Khedr, Angelo Paduano, Francesco Scarano, Lucas Meirelles, Julio Cordioli","doi":"10.1038/s44384-026-00044-x","DOIUrl":"10.1038/s44384-026-00044-x","url":null,"abstract":"The impact of minor manufacturing deviations in facesheet orifice geometries on the acoustic impedance of liners is studied. Using the lattice-Boltzmann method, simulations of a normal impedance tube (NIT) with plane acoustic waves at sound pressure levels of 130 and 145 dB and frequencies of 800, 1400, and 2000 Hz were performed. Experimental validation was conducted at the Federal University of Santa Catarina using a baseline geometry obtained via 3D scanning and characterized by rounded orifice edges. This geometry was modified to investigate the influence of various edge configurations: sharp edges, double chamfers, and single top chamfers. Results show that sharp-edged orifices increase acoustic resistance and absorption, while geometries with rounded or chamfered edges reduce resistance by up to 28% and lower the absorption coefficient. This is similar to what was found experimentally by performing NIT measurements over different parts of the liner sample. Velocity field analysis reveals that flow separation at the orifice edge is the primary mechanism driving impedance variation, independent of frequency or sound pressure level. These findings underscore the significant influence of small geometric imperfections, often introduced during manufacturing, on liner performance, highlighting the need to consider such variations in industrial design and quality assurance processes.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12913017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soundscape experience activities and mapping. 音景体验活动和映射。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-02-23 DOI: 10.1038/s44384-025-00041-6

Thomas Deacon, David Frohlich, Mark D Plumbley

{"title":"Soundscape experience activities and mapping.","authors":"Thomas Deacon, David Frohlich, Mark D Plumbley","doi":"10.1038/s44384-025-00041-6","DOIUrl":"10.1038/s44384-025-00041-6","url":null,"abstract":"This paper presents Soundscape Experience Activities and Mapping (SEAM), a new method for exploring how older adults perceive and relate to their indoor acoustic environments. With global ageing, populations are increasingly choosing to age in place, creating opportunities to enhance older life through the intentional design of supportive home soundscapes. Through a mixed-method approach combining Ecological Momentary Assessment with Cultural Probe methods, we engaged eight older adults (age 56-76) in Belgium to document their domestic soundscape experiences. Reflexive thematic analysis constructed four patterns of meaning: personal agency in shaping acoustic environments, temporal routines structured by sound, sound-memory associations fostering place attachment, and social presence through acoustic monitoring. Within this study context, sounds functioned as spatiotemporal anchors, structuring daily routines while fostering place attachment through memory. This exploratory design research offers situated insights for soundscape interventions that support independence, while highlighting methodological considerations for situated soundscape research.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12929050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147314286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Composing with acoustic niches: A laboratory soundscape evaluation of sound installation reactivity. 用声学壁龛作曲：声音装置反应性的实验室声景评价。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-09-02 DOI: 10.1038/s44384-026-00066-5

Valérian Fraisse, Nadine Schütz, Coralie Vincent, Marcelo M Wanderley, Catherine Guastavino, Nicolas Misdariis

{"title":"Composing with acoustic niches: A laboratory soundscape evaluation of sound installation reactivity.","authors":"Valérian Fraisse, Nadine Schütz, Coralie Vincent, Marcelo M Wanderley, Catherine Guastavino, Nicolas Misdariis","doi":"10.1038/s44384-026-00066-5","DOIUrl":"10.1038/s44384-026-00066-5","url":null,"abstract":"Sound installations can shape the soundscape of public spaces. However, few studies have examined their impact on perceptual evaluations, especially in relation to the pre-existing sound environment. We report on an exploratory study investigating the effect of sound installations on soundscape evaluation, specifically manipulating compositional and acoustic reactivity in laboratory settings. This research is part of a research-creation collaboration around Nadine Schütz's Niches Acoustiques-a new permanent installation for a public square in Paris. Participants familiar with the public space (N = 37) evaluated soundscapes combining High-Order Ambisonics field recordings with simulations of the installation with different forms of reactivity, along different time contexts and associated space uses-amplifying, attenuating, or transforming its content in relation to the pre-existing sound environment. Results show that time context strongly modulates soundscape impact of scenario-specific compositions changing according to daytimes and weekdays. There is greater potential for improving soundscape's pleasantness and variety in quieter, less unpleasant settings, highlighting the difficulty of enhancing pleasantness in unpleasant, traffic-dominated soundscapes. Moreover, acoustic reactivity can modulate these effects in relation to context: results suggest that following spectrotemporal trends might be more effective in noisy contexts, while occupying spectrotemporal niches might suit calmer ones. Together, these findings reveal how installation reactivity can meaningfully shape public spaces' soundscapes.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"33"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13538143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harnessing normal-shear coupling in metabarriers for deep sub-wavelength underwater noise control. 利用超势垒中的法向-剪切耦合控制深亚波长水下噪声。

NPJ acoustics Pub Date : 2026-01-01 Epub Date: 2026-05-18 DOI: 10.1038/s44384-026-00056-7

Vinícius F Dal Poggetto, Marco Miniaci

{"title":"Harnessing normal-shear coupling in metabarriers for deep sub-wavelength underwater noise control.","authors":"Vinícius F Dal Poggetto, Marco Miniaci","doi":"10.1038/s44384-026-00056-7","DOIUrl":"10.1038/s44384-026-00056-7","url":null,"abstract":"Anthropogenic underwater noise poses a significant threat to marine ecosystems, disrupting key biological functions. Common mitigation strategies include enclosing noise sources within acoustic barriers. Current designs include locally resonant absorbers, which offer narrow-band performance, and reflective systems with limited effectiveness at low frequencies. In this work, we propose an approach to design thin anisotropic metamaterial-based acoustic barriers for broadband underwater noise attenuation at deep sub-wavelength scales using topology optimization to maximize the coupling between normal stresses and shear strains. Unlike conventional methods, the proposed optimization is formulated in the static regime, relying solely on the homogenized elastic properties of the structured material and not on the characteristics of the surrounding fluid. The resulting metabarriers achieve a high sound transmission loss (STL, 100 dB peak) above 2 kHz, while maintaining a thickness-to-wavelength ratio as low as 1/70 below 1 kHz and STL of approximately 20-30 dB. The influence of hydrostatic pressure on performance is also evaluated, and structural modifications for practical deployment are proposed. The results demonstrate the potential of anisotropy-driven metamaterials as compact and efficient solutions for the control of underwater noise, offering a promising avenue for future acoustic insulation technologies.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"2 1","pages":"20"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13183581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147985045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Achieving single cell acoustic localisation with deactivation super resolution. 通过失活超分辨率实现单细胞声学定位。

NPJ acoustics Pub Date : 2025-01-01 Epub Date: 2025-04-24 DOI: 10.1038/s44384-025-00008-7

Cameron A B Smith, Mengtong Duan, Jipeng Yan, Laura Taylor, Mikhail Shapiro, Meng-Xing Tang

引用次数: 0

Aeroacoustics and psychoacoustics characterization of a boundary layer ingesting ducted fan. 边界层吸入式导管风扇的气动声学和心理声学特性。

NPJ acoustics Pub Date : 2025-01-01 Epub Date: 2025-05-15 DOI: 10.1038/s44384-025-00010-z

Feroz Ahmed, Carlos Ramos-Romero, Antonio J Torija, Mahdi Azarpeyvand

{"title":"Aeroacoustics and psychoacoustics characterization of a boundary layer ingesting ducted fan.","authors":"Feroz Ahmed, Carlos Ramos-Romero, Antonio J Torija, Mahdi Azarpeyvand","doi":"10.1038/s44384-025-00010-z","DOIUrl":"10.1038/s44384-025-00010-z","url":null,"abstract":"A comprehensive wind tunnel investigation was conducted to analyze noise generation, propagation, and perception mechanisms in a boundary layer ingesting (BLI) ducted fan through integrated aeroacoustic and psychoacoustic assessments. The study examines interactions between an incoming adverse pressure gradient turbulent boundary layer flow, developed over a curved wall, and the ducted fan. The fundamental investigation confirms that the fan thrust regime influences aerodynamic, aeroacoustic, and psychoacoustic characteristics, exhibiting various haystacking phenomena. High-thrust operation induces a pronounced upstream suction effect, accelerating the boundary layer flow, amplifying bulk momentum, and intensifying turbulence ingestion, leading to fan aeroacoustics and associated fan haystacking in noise spectrum. In contrast, low-thrust operation minimally alters the boundary layer flow, with reduced suction and noise dominated by duct aeroacoustics and the associated duct haystacking due to interactions between ingested turbulence and the duct's acoustic field. The psychoacoustic assessments indicate that both fan and duct haystacking contribute to higher perceived noise in the high- and low-thrust regime, respectively.","PeriodicalId":520425,"journal":{"name":"NPJ acoustics","volume":"1 1","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0