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Cutaneous ulcers in patients with chronic graft-versus-host disease: A systematic review. 慢性移植物抗宿主病患者的皮肤溃疡：一项系统综述
JAAD reviews Pub Date : 2025-06-01 Epub Date: 2025-03-30 DOI: 10.1016/j.jdrv.2025.03.017
Trang M Nguyen, Giang Huong Nguyen, Tung S Tran, Benjamin H Kaffenberger, Edward W Cowen, Afsaneh Alavi
{"title":"Cutaneous ulcers in patients with chronic graft-versus-host disease: A systematic review.","authors":"Trang M Nguyen, Giang Huong Nguyen, Tung S Tran, Benjamin H Kaffenberger, Edward W Cowen, Afsaneh Alavi","doi":"10.1016/j.jdrv.2025.03.017","DOIUrl":"10.1016/j.jdrv.2025.03.017","url":null,"abstract":"","PeriodicalId":520419,"journal":{"name":"JAAD reviews","volume":"4 ","pages":"175-177"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric psoriasis: Biologics and oral small molecule inhibitors in modern therapy. 小儿牛皮癣：生物制剂和口服小分子抑制剂在现代治疗中的应用。
JAAD reviews Pub Date : 2025-03-01 Epub Date: 2024-12-19 DOI: 10.1016/j.jdrv.2024.12.008
Alexandra Firek, Leslie Castelo-Soccio
{"title":"Pediatric psoriasis: Biologics and oral small molecule inhibitors in modern therapy.","authors":"Alexandra Firek, Leslie Castelo-Soccio","doi":"10.1016/j.jdrv.2024.12.008","DOIUrl":"10.1016/j.jdrv.2024.12.008","url":null,"abstract":"<p><p>Therapeutic options are expanding for pediatric patients with psoriasis. Here, we offer an overview of the current treatment landscape for pediatric psoriasis, focusing on the increasing role of biologics and oral small molecules. Each therapeutic is discussed in terms of dosage, safety profile, and assessment through measures such as the Psoriasis Area Severity Index and the Children's Dermatology Life Quality Index, where data are available. We highlight the important pediatric-specific clinical trials as well as infer potential for pediatric therapy based on available adult trials. There has been a steady increase in pediatric psoriasis trials, but there is a continued need for more pediatric-focused research. Additional trials and therapeutics that match adult trials would substantially refine therapeutic decision-making and improve outcomes in this demographic.</p>","PeriodicalId":520419,"journal":{"name":"JAAD reviews","volume":"3 ","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11815549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biopsychosocial impact of keloids on quality of life. 瘢痕疙瘩对生活质量的生物-心理-社会影响。
JAAD reviews Pub Date : 2024-12-01 Epub Date: 2024-08-23 DOI: 10.1016/j.jdrv.2024.08.010
Megan Mathew, Gabrielle DiBartolomeo, Rivka C Stone
{"title":"Biopsychosocial impact of keloids on quality of life.","authors":"Megan Mathew, Gabrielle DiBartolomeo, Rivka C Stone","doi":"10.1016/j.jdrv.2024.08.010","DOIUrl":"10.1016/j.jdrv.2024.08.010","url":null,"abstract":"<p><p>Keloids are a prevalent, although understudied, dermatologic condition commonly affecting people of color. In the clinical setting, keloids negatively impact many aspects of patient quality of life (QoL), but this area has not been comprehensively characterized. This review identifies and summarizes studies in which the QoL impact of keloids has been measured utilizing validated survey and questionnaire instruments, including the SCAR-Q and Dermatology Life Quality Index. Study findings are grouped into physical and emotional factors that together comprise 7 biopsychosocial domains: pain and itch, mobility, visibility, gender and age, psychosocial, stigma, and cosmetic. These domains interact in a complex network that negatively impacts QoL of patients with keloid. Enhanced understanding of the significance of these domains will pave the way for the performance of large, rigorous epidemiologic studies that will lead to the development of efficacious keloid therapies that improve not only physical but also psychosocial functioning, enabling clinicians to provide holistic care that enhances patient QoL.</p>","PeriodicalId":520419,"journal":{"name":"JAAD reviews","volume":"2 ","pages":"13-19"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144777642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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